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Invitrogen
GSDMB (Cleaved) Recombinant Rabbit Monoclonal Antibody (6F4K3)
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GSDMB (Cleaved) Antibody (MA5-55412) in WB
Western blot analysis of lysates from 293T GSDMB stable cells and 293T GSDMB stable cells transfected with GZMA using GSDMB (Cleaved) Recombinant Monoclonal Antibody (Product # MA5-55412) at 1:1,000 dilution followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) secondary antibody at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
MA5-55412
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6F4K3
Immunogen
A synthetic peptide corresponding to residues surrounding Ser245 of human Gasdermin B.
Conjugate
Form
Liquid
Concentration
1.11 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
AB_3667653
Product Specific Information
Immunogen Sequence: GKSLG
Target Information
GSDMB (Cleaved) refers to the gene target Gasdermin B, which undergoes cleavage to produce active fragments. Gasdermin B is a protein that plays a role in the regulation of cell death and inflammation. Cleavage of GSDMB leads to the release of its N-terminal fragment, which can initiate a process called pyroptosis, a type of programmed cell death. Pyroptosis is an inflammatory form of cell death that is triggered by various stimuli, including infection and cellular stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gasdermin B; Gasdermin-B; Gasdermin-like protein
Gene Aliases: GSDMB; GSDML; PP4052; PRO2521
UniProt ID: (Human) Q8TAX9
Entrez Gene ID: (Human) 55876
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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