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Bioss
GSK3B interacting protein Polyclonal Antibody
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FIGURE: 1 / 3
GSK3B interacting protein Antibody (BS-7844R) in IHC (P)
Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Ninein/GSK3B interacting protein Polyclonal Antibody, Unconjugated(bs-7844R) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C.
Product Details
BS-7844R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Ninein, amino acids 133-230.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GSK3-beta interaction protein; GSK3B-interacting protein; GSK3beta interaction protein; GSKIP; MGC4945
Gene Aliases: 4933433P14Rik; C14orf129; GSKIP; HSPC210; RGD1308470
UniProt ID: (Human) Q9P0R6, (Mouse) Q8BGR8, (Rat) Q5PPI3
Entrez Gene ID: (Human) 51527, (Mouse) 66787, (Rat) 362778
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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