Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
GSTA3/GSTA5 Polyclonal Antibody
Product Details
PA5-142682
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-EMDPGIVDNFPLLK.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933328
Product Specific Information
Additional Information: This antibody is expected to cross-react to the homologous Mouse protein Gsta3.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GHS transferase; Glutathione S-transferase A3; Glutathione S-transferase alpha-2; Glutathione S-transferase alpha-5; glutathione S-transferase Ya subunit; Glutathione S-transferase Ya-2; Glutathione S-transferase Ya3; Glutathione S-transferase Yc; Glutathione S-transferase Yc-2; glutathione S-transferase Yc2 subunit; glutathione transferase YA subunit; GST 1b-1b; GST A2-2; GST A5-5; GST class-alpha member 3; GST Ya2; GST Yc2; uncharacterized protein LOC100042314
Gene Aliases: ENSMUSG00000074179; Gst2-3; Gsta2; Gsta3; Gsta5; Gstyc; Gstyc2; Yc2
UniProt ID: (Mouse) P30115, (Rat) P46418, (Rat) P04903
Entrez Gene ID: (Mouse) 100042314, (Mouse) 14859, (Rat) 494500, (Rat) 494499
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support