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Invitrogen
GSTM1 Monoclonal Antibody (1H4F2)
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Product Details
MA5-17085
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H4F2
Immunogen
Purified recombinant fragment of human GSTM1 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538556
Product Specific Information
MA5-17085 targets GSTM1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Rat samples.
The MA5-17085 immunogen is purified recombinant fragment of human GSTM1 expressed in E. Coli.
MA5-17085 detects GSTM1 which has a predicted molecular weight of approximately 26kDa.
Target Information
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; Glutathione S-transferase Mu 1; Glutathione S-transferase Yb-1; glutathione S-transferase Yb-1 subunit; glutathione-S-transferase mu type 1 (Yb1); glutathione-S-transferase, mu type 1 (Yb1); GST 3-3; GST class-mu 1; GST HB subunit 4; GST Yb1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; HB subunit 4; S-(hydroxyalkyl)glutathione lyase
Gene Aliases: GST1; GSTA3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1
UniProt ID: (Human) P09488, (Rat) P04905
Entrez Gene ID: (Human) 2944, (Rat) 24423
glutathione metabolic process
sensory perception of smell
metabolic process
response to metal ion
response to lithium ion
response to lead ion
nitrobenzene metabolic process
cellular response to drug
xenobiotic catabolic process
response to drug
response to amino acid
response to ethanol
response to antibiotic
response to axon injury
cellular detoxification of nitrogen compound
glutathione derivative biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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