Proteintech

GSTZ1 Polyclonal Antibody

GSTZ1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

GSTZ1 Antibody (14889-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using (Product # 14889-1-AP) (GSTZ1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Product Details

14889-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GSTZ1 Fusion Protein Ag6676 (1-216 aa encoded by BC001453)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MQAGKPILY SYFRSSCSWR VRIALALKGI DYETVPINLI KDGGQQFSKD FQALNPMKQV PTLKIDGITI HQSLAIIEYL EEMRPTPRLL PQDPKKRASV RMISDLIAGG IQPLQNLSVL KQVGEEMQLT WAQNAITCGF NALEQILQST AGIYCVGDEV TMADLCLVPQ VANAERFKVD LTPYPTISSI NKRLLVLEAF QVSHPCRQPD TPTELRA (1-216 aa encoded by BC001453)

Target Information

This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target.

ACS chemical biology

Liao Y,Chin Chan S,Welsh EA,Fang B,Sun L,Schönbrunn E,Koomen JM,Duckett DR,Haura EB,Monastyrskyi A,Rix U

Fri Feb 17 00:00:00 UTC 2023

Identification and validation of a tyrosine metabolism-related prognostic prediction model and characterization of the tumor microenvironment infiltration in hepatocellular carcinoma.

Frontiers in immunology

Zhou Y,Li X,Long G,Tao Y,Zhou L,Tang J

Tue Nov 08 00:00:00 UTC 2022

Integrated proteomics and metabolomics analysis of lumbar in a rat model of osteoporosis treated with Gushukang capsules.

BMC complementary medicine and therapies

Lin R,Xie B,Xie L,Ge J,Li S

Thu Dec 15 00:00:00 UTC 2022

Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

The journals of gerontology. Series A, Biological sciences and medical sciences

Rojanathammanee L,Rakoczy S,Brown-Borg HM

Wed Oct 01 00:00:00 UTC 2014

Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

The journals of gerontology. Series A, Biological sciences and medical sciences

Rojanathammanee L,Rakoczy S,Brown-Borg HM

Wed Oct 01 00:00:00 UTC 2014

Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Age (Dordrecht, Netherlands)

Rojanathammanee L,Rakoczy S,Kopchick J,Brown-Borg HM

Tue Mar 31 00:00:00 UTC 2015

Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Age (Dordrecht, Netherlands)

Rojanathammanee L,Rakoczy S,Kopchick J,Brown-Borg HM

Tue Mar 31 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase alpha 3; Glutathione S-transferase zeta 1; glutathione transferase zeta 1; GSTZ1-1; MAAI; Maleylacetoacetate isomerase; maleylacetone isomerase; S-(hydroxyalkyl)glutathione lyase

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Gene Aliases: GSTZ1; GSTZ1-1; MAAI; MAI

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UniProt ID: (Human) O43708, (Rat) P57113, (Mouse) Q9WVL0

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Entrez Gene ID: (Human) 2954, (Rat) 681913, (Mouse) 14874

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Function(s)

glutathione transferase activity glutathione peroxidase activity protein binding maleylacetoacetate isomerase activity protein homodimerization activity catalytic activity transferase activity isomerase activity

Process(es)

L-phenylalanine catabolic process tyrosine catabolic process glutathione metabolic process cellular oxidant detoxification glutathione derivative biosynthetic process metabolic process aromatic amino acid family metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GSTZ1 Polyclonal Antibody

GSTZ1 Antibody (14889-1-AP) in IHC (P)

Product Details

14889-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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