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Product Details
H00079712-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GTDC1 (NP_078935, 1 a.a. approximately 373 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSILIIEAFY GGSHKQLVDL LQEELGDCVV YTLPAKKWHW RARTSALYFS QTIPISEHYR TLFASSVLNL TELAALRPDL GKLKKILYFH ENQLIYPVKK CQERDFQYGY NQILSCLVAD VVVFNSVFNM ESFLTSMGKF MKLIPDHRPK DLESIIRPKC QVIYFPIRFP DVSRFMPKHK TTHLKKMLGL KGNGGAVLSM ALPFQPEQRD SEDLLKNFNS ECDTHCGLDT ARQEYLGNSL RQESDLKKST SSDNSSSHHG ENKQNLTVDP CDILGGVDNQ QRLLHIVWPH RWLEAVYCGC YPLCPKDLVY PEIFPAEYLY STPEQLSKRL QNFCKRPDII RKHLYKGEIA PFSWAALHGK FRSLLTTEPR EDL
Target Information
The GTDC1 (Glycosyltransferase-Like Domain Containing 1) gene encodes a protein that is hypothesized to function as a glycosyltransferase. This gene has been implicated in several crucial biological processes, particularly in the nervous system. The GTDC1 cDNA is 2954 base pairs in length, encoding a protein of 458 amino acids, and shows high expression in tissues such as the lung, spleen, testis, and peripheral blood leukocytes. Genetic studies have highlighted its potential role in developmental disorders, such as global developmental delay and delayed speech and language development, linked to microdeletions encompassing the GTDC1 gene. Disruption of GTDC1 expression has been shown to affect neural progenitor cells and neurons, indicating its significance in neural development. Additionally, the gene holds evolutionary conservation, sharing 75% and 37% identity with its mouse and fruit fly counterparts, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycosyltransferase-like 1; glycosyltransferase-like domain containing 1; Glycosyltransferase-like domain-containing protein 1; mannosyltransferase candidate; Mannosyltransferase-like protein Xa; Mat-Xa; QTMAN; tRNA-queuosine alpha-mannosyltransferase
Gene Aliases: GTDC1; Hmat-Xa; mat-Xa; QTMAN
UniProt ID: (Human) Q4AE62
Entrez Gene ID: (Human) 79712
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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