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Invitrogen
GTF2F2 Recombinant Rabbit Monoclonal Antibody (JE56-15)
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FIGURE: 1 / 5
GTF2F2 Antibody (MA5-42489) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human placenta tissue using GTF2F2 Recombinant Monoclonal Antibody (Product # MA5-42489). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the GTF2F2 antibody a... View More
Product Details
MA5-42489
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE56-15
Immunogen
Synthetic peptide within C-terminal Human GTF2F2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911630
Product Specific Information
Positive Control: Rat testis tissue lysate, A549 cell lysate, HepG2 cell lysate, HL-60 cell lysate, THP-1 cell lysate, Daudi cell lysate, rat testis tissue, human skin tissue, human placenta tissue, human uterus tissue.
Subcellular Location: Nucleus.
Target Information
GTF2F2 is required for both basal and HIV-1 Tat-activated transcription. GTF2F2 synergizes with HIV-1 Tat and the cellular co-activator Tat-SF1 during Tat-mediated transactivation of the HIV-1 LTR promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent helicase GTF2F2; General transcription factor IIF 30 kDa subunit; General transcription factor IIF subunit 2; general transcription factor IIF, polypeptide 2 (30kD subunit); general transcription factor IIF, polypeptide 2, 30kDa; TFIIF beta; TFIIF-beta; transcription factor gamma; Transcription initiation factor IIF subunit beta; Transcription initiation factor RAP30
Gene Aliases: BTF4; GTF2F2; RAP30; TF2F2; TFIIF
UniProt ID: (Human) P13984
Entrez Gene ID: (Human) 2963, (Rat) 81674
mRNA splicing, via spliceosome
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
positive regulation of transcription elongation from RNA polymerase II promoter
snRNA transcription from RNA polymerase II promoter
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of viral transcription
positive regulation of transcription initiation from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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