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OriGene
GTF3C4 Monoclonal Antibody (OTI4A1), TrueMAB™
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FIGURE: 1 / 11
GTF3C4 Antibody (CF812628) in IHC (P)
Immunohistochemical staining of paraffin-embedded human pancreas tissue within the normal limits using anti-GTF3C4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA812628)(1:500).
Product Details
CF812628
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4A1
Immunogen
Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: general transcription factor 3C 4; General transcription factor 3C polypeptide 4; general transcription factor IIIC 4; general transcription factor IIIC, polypeptide 4, 90kDa; TF3C-delta; TFIIIC 90 kDa subunit; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta
Gene Aliases: 5330400C03; AI426938; AU014771; AU017413; GTF3C4; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA
UniProt ID: (Human) Q9UKN8, (Mouse) Q8BMQ2
Entrez Gene ID: (Human) 9329, (Mouse) 269252, (Rat) 685539
transcription, DNA-templated
biological_process
transcription from RNA polymerase III promoter
transcription initiation from RNA polymerase III promoter
histone acetylation
5S class rRNA transcription from RNA polymerase III type 1 promoter
tRNA transcription from RNA polymerase III promoter
positive regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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