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Immunogen sequence: HALRILTAPR DLPLARHASL RLLSDPRSGE PLDRALVLWF PGPQSFTGED CVEFHVHGGP AVVSGVLQAL GSVPGLRPAE AGEFTRRAFA NGKLNL
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GTP-binding protein 3; Mitochondrial GTP-binding protein 1; tRNA modification GTPase GTPBP3, mitochondrial
Gene Aliases: COXPD23; GTPBG3; GTPBP3; MSS1; MTGP1; THDF1
UniProt ID: (Human) Q969Y2
Entrez Gene ID: (Human) 84705
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