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GUSB Polyclonal Antibody

GUSB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 8

GUSB Antibody (16332-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using 16332-1-AP (GUSB Antibody) at dilution of 1:50 (under 40x lens).

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Product Details

16332-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GUSB Fusion Protein Ag9453 (302-651 aa encoded by BC014142)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SLEVQLTAQ TSLGPVSDFY TLPVGIRTVA VTKSQFLING KPFYFHGVNK HEDADIRGKG FDWPLLVKDF NLLRWLGANA FRTSHYPYAE EVMQMCDRYG IVVIDECPGV GLALPQFFNN VSLHHHMQVM EEVVRRDKNH PAVVMWSVAN EPASHLESAG YYLKMVIAHT KSLDPSRPVT FVSNSNYAAD KGAPYVDVIC LNSYYSWYHD YGHLELIQLQ LATQFENWYK KYQKPIIQSE YGAETIAGFH QDPPLMFTEE YQKSLLEQYH LGLDQKRRKY VVGELIWNFA DFMTEQSPTR VLGNKKGIFT RQRQPKSAAF LLRERYWKIA NETRYPHSVA KSQCLENSLF T (302-651 aa encoded by BC014142)

Target Information

The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It is a tetrameric glycoprotein composed of identical subunits. The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses.

The Journal of investigative dermatology

Yamaguchi K,Kanno E,Tanno H,Sasaki A,Kitai Y,Miura T,Takagi N,Shoji M,Kasamatsu J,Sato K,Sato Y,Niiyama M,Goto Y,Ishii K,Imai Y,Saijo S,Iwakura Y,Tachi M,Kawakami K

Fri Jan 01 00:00:00 UTC 2021

The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation.

Science (New York, N.Y.)

Martin TD,Patel RS,Cook DR,Choi MY,Patil A,Liang AC,Li MZ,Haigis KM,Elledge SJ

Fri Sep 17 00:00:00 UTC 2021

C-Type Lectin Receptor Dectin-2 Binds to an Endogenous Protein β-Glucuronidase on Dendritic Cells.

PloS one

Mori D,Shibata K,Yamasaki S

Mon Aug 21 00:00:00 UTC 2017

C-Type Lectin Receptor Dectin-2 Binds to an Endogenous Protein β-Glucuronidase on Dendritic Cells.

PloS one

Mori D,Shibata K,Yamasaki S

Mon Aug 21 00:00:00 UTC 2017

Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages.

PloS one

Ishisaka A,Kawabata K,Miki S,Shiba Y,Minekawa S,Nishikawa T,Mukai R,Terao J,Kawai Y

Tue Aug 26 00:00:00 UTC 2014

Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages.

PloS one

Ishisaka A,Kawabata K,Miki S,Shiba Y,Minekawa S,Nishikawa T,Mukai R,Terao J,Kawai Y

Tue Aug 26 00:00:00 UTC 2014

Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration.

PloS one

Wang AL,Lukas TJ,Yuan M,Du N,Handa JT,Neufeld AH

Mon Jul 27 00:00:00 UTC 2009

Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration.

PloS one

Wang AL,Lukas TJ,Yuan M,Du N,Handa JT,Neufeld AH

Mon Jul 27 00:00:00 UTC 2009

Bioinformatics

Protein Aliases: adipose storage deficiency; beta glucuronidase; beta-D-glucuronidase; Beta-G1; Beta-glucuronidase; glucuronidase, beta

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Gene Aliases: Ac2-223; AI747421; asd; BG; g; Gur; Gus; Gus-r; Gus-s; Gus-t; Gus-u; GUSB; Gut; MPS7

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UniProt ID: (Human) P08236, (Rat) P06760, (Mouse) P12265

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Entrez Gene ID: (Human) 2990, (Rat) 24434, (Mouse) 110006

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Function(s)

beta-glucuronidase activity receptor binding protein domain specific binding carbohydrate binding hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity hydrolase activity, acting on glycosyl bonds

Process(es)

carbohydrate metabolic process glycosaminoglycan catabolic process hyaluronan catabolic process metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GUSB Polyclonal Antibody

GUSB Antibody (16332-1-AP) in IHC (P)

Product Details

16332-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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