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This antibody is raised against the full-length protein of human Glycophorin-C. The apparent molecular weight of Glycophorin-C is lager than the calculated molecular weight due to glycosylation.
Immunogen sequence: MWSTRSPNS TAWPLSLEPD PGMASASTTM HTTTIAEPDP GMSGWPDGRM ETSTPTIMDI VVIAGVIAAV AIVLVSLLFV MLRYMYRHKG TYHTNEAKGT EFAESADAAL QGDPALQDAG DSSRKEYFI (1-128 aa encoded by BC106051 )
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD236; Glycoconnectin; Glycophorin-C; Glycophorin-D; Glycoprotein beta; GPD; GPYD; MGC117309; MGC126191; MGC126192; PAS-2'; Sialoglycoprotein D
Gene Aliases: CD236; CD236R; GE; GLPC; GPC; GPD; GYPC; GYPD; PAS-2; PAS-2'
UniProt ID: (Human) P04921
Entrez Gene ID: (Human) 2995
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