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GYS1 Polyclonal Antibody

GYS1 Antibody in Immunocytochemistry (ICC/IF)

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GYS1 Antibody (10566-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 10566-1-AP (GYS1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

GYS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GYS1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10566-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GYS1 Fusion Protein Ag0857 (430-737 aa encoded by BC007688)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RAIFATQRQ SFPPVCTHNM LDDSSDPILT TIRRIGLFNS SADRVKVIFH PEFLSSTSPL LPVDYEEFVR GCHLGVFPSY YEPWGYTPAE CTVMGIPSIS TNLSGFGCFM EEHIADPSAY GIYILDRRFR SLDDSCSQLT SFLYSFCQQS RRQRIIQRNR TERLSDLLDW KYLGRYYMSA RHMALSKAFP EHFTYEPNEA DAAQGYRYPR PASVPPSPSL SRHSSPHQSE DEEDPRNGPL EEDGERYDED EEAAKDRRNI RAPEWPRRAS CTSSTSGSKR NSVDTATSSS LSTPSEPLSP TSSLGEERN (430-737 aa encoded by BC007688)

Target Information

Glycogen Synthase 1 (GYS1) catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.

International journal of biological sciences

Ji Q,Li H,Cai Z,Yuan X,Pu X,Huang Y,Fu S,Chu L,Jiang C,Xue J,Zhang X,Li R

Wed Apr 19 00:00:00 UTC 2023

Identification of novel immune subtypes and potential hub genes of patients with psoriasis.

Journal of translational medicine

Li Y,Li L,Tian Y,Luo J,Huang J,Zhang L,Zhang J,Li X,Hu L

Wed Mar 08 00:00:00 UTC 2023

Douchi Peptides VY and SFLLR Improve Glucose Homeostasis and Gut Dysbacteriosis in High-Fat Diet-Induced Insulin Resistant Mice.

Molecular nutrition & food research

Yu S,Wang W,Wang H,Bu T,Liu L,Zhao R,Li S,Liu D,Wu J

Mon May 01 00:00:00 UTC 2023

Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or systemic lipolysis in rat.

Metabolism: clinical and experimental

Liu Z,Zhang L,Qian C,Zhou Y,Yu Q,Yuan J,Lv Y,Zhang L,Chang X,Li Y,Liu Y

Tue Nov 01 00:00:00 UTC 2022

Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight.

Frontiers in endocrinology

Doi M,Nakama N,Sumi T,Usui N,Shimada S

Fri Nov 11 00:00:00 UTC 2022

Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.

Journal of immunology (Baltimore, Md. : 1950)

Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN

Tue Nov 01 00:00:00 UTC 2022

Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

The Journal of investigative dermatology

Gu Z,Zhang H,Guo X,Cao Y

Sat Aug 01 00:00:00 UTC 2020

Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

The Journal of investigative dermatology

Gu Z,Zhang H,Guo X,Cao Y

Sat Aug 01 00:00:00 UTC 2020

Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.

Toxicology

Wang F,Chang C,Li R,Zhang Z,Jiang H,Zeng N,Li D,Chen L,Xiao Y,Chen W,Wang Q

Thu Aug 01 00:00:00 UTC 2019

ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.

Biochemical and biophysical research communications

Dong K,Ni H,Wu M,Tang Z,Halim M,Shi D

Fri Aug 05 00:00:00 UTC 2016

ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.

Biochemical and biophysical research communications

Dong K,Ni H,Wu M,Tang Z,Halim M,Shi D

Fri Aug 05 00:00:00 UTC 2016

Inducible metabolic adaptation promotes mesenchymal stem cell therapy for ischemia: a hypoxia-induced and glycogen-based energy prestorage strategy.

Arteriosclerosis, thrombosis, and vascular biology

Zhu H,Sun A,Zou Y,Ge J

Tue Apr 01 00:00:00 UTC 2014

Inducible metabolic adaptation promotes mesenchymal stem cell therapy for ischemia: a hypoxia-induced and glycogen-based energy prestorage strategy.

Arteriosclerosis, thrombosis, and vascular biology

Zhu H,Sun A,Zou Y,Ge J

Tue Apr 01 00:00:00 UTC 2014

A single centrifugation method for isolating fat droplets from cells and tissues.

Journal of lipid research

Harris LLS,Shew TM,Skinner JR,Wolins NE

Tue May 01 00:00:00 UTC 2012

A single centrifugation method for isolating fat droplets from cells and tissues.

Journal of lipid research

Harris LLS,Shew TM,Skinner JR,Wolins NE

Tue May 01 00:00:00 UTC 2012

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Journal of lipid research

Hall AM,Brunt EM,Chen Z,Viswakarma N,Reddy JK,Wolins NE,Finck BN

Mon Mar 01 00:00:00 UTC 2010

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Journal of lipid research

Hall AM,Brunt EM,Chen Z,Viswakarma N,Reddy JK,Wolins NE,Finck BN

Mon Mar 01 00:00:00 UTC 2010

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Journal of lipid research

Hall AM,Brunt EM,Chen Z,Viswakarma N,Reddy JK,Wolins NE,Finck BN

Mon Mar 01 00:00:00 UTC 2010

Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Journal of lipid research

Hall AM,Brunt EM,Chen Z,Viswakarma N,Reddy JK,Wolins NE,Finck BN

Mon Mar 01 00:00:00 UTC 2010

Bioinformatics

Protein Aliases: EC 2.4.1.11; Glycogen [starch] synthase, muscle; glycogen synthase; Glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 3, brain

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Gene Aliases: GSY; GYS; GYS1; Gys3; MGS

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UniProt ID: (Human) P13807, (Rat) A2RRU1, (Mouse) Q9Z1E4

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Entrez Gene ID: (Human) 2997, (Rat) 690987, (Mouse) 14936

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Function(s)

glycogen (starch) synthase activity protein binding glucose binding protein kinase binding glycogen synthase activity, transferring glucose-1-phosphate catalytic activity transferase activity transferase activity, transferring glycosyl groups

Process(es)

glycogen metabolic process glycogen biosynthetic process heart development metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GYS1 Polyclonal Antibody

GYS1 Antibody (10566-1-AP) in ICC/IF

Product Details

10566-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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