Proteintech

Galectin 9 Polyclonal Antibody

View all (43) Galectin 9 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (8)

Galectin 9 Antibody in Immunocytochemistry (ICC/IF)

Galectin 9 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

Galectin 9 Antibody (17938-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 17938-1-AP (Galectin 9 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Galectin 9 Antibody in Immunocytochemistry (ICC/IF)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Western Blot (WB)

Galectin 9 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Galectin 9 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 17938-1-AP (Galectin 9 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Galectin 9 Antibody in Western Blot (WB) — WB result of Galectin 9 antibody (Product # 17938-1-AP) 1:2,000, incubated at room temperature for 1.5 hours with sh-Control and sh-Galectin 9 transfected NIH/3T3 cells.

Galectin 9 Antibody in Western Blot (WB) — SGC-7901 cells were subjected to SDS PAGE followed by western blot with 17938-1-AP (Galectin 9 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

Galectin 9 Antibody in Western Blot (WB) — HL-60 cells were subjected to SDS PAGE followed by western blot with 17938-1-AP (Galectin 9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Galectin 9 Antibody in Western Blot (WB) — HepG2 cells were subjected to SDS PAGE followed by western blot with 17938-1-AP (Galectin 9 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Galectin 9 Antibody in Western Blot (WB) — U-937 cells were subjected to SDS PAGE followed by western blot with 17938-1-AP ( Galectin 9 antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

Galectin 9 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 17938-1-AP (Galectin 9 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Galectin 9 Antibody in Immunoprecipitation (IP) — IP result of anti-Galectin 9 (IP: 17938-1-AP, 4 µg; Detection: 17938-1-AP 1:500) with SGC-7901 cells lysate 2400 µg.

Product Details

17938-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

Assay-dependent

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

-

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

-

View 1 publication 1 publication

Not applicable (N/A)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Galectin 9 Fusion Protein Ag12209 (1-323 aa encoded by BC110340)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAFSGSQAP YLSPAVPFSG TIQGGLQDGL QITVNGTVLS SSGTRFAVNF QTGFSGNDIA FHFNPRFEDG GYVVCNTRQN GSWGPEERKT HMPFQKGMPF DLCFLVQSSD FKVMVNGILF VQYFHRVPFH RVDTISVNGS VQLSYISFQP PGVWPANPAP ITQTVIHTVQ SAPGQMFSTP AIPPMMYPHP AYPMPFITTI LGGLYPSKSI LLSGTVLPSA QRFHINLCSG NHIAFHLNPR FDENAVVRNT QIDNSWGSEE RSLPRKMPFV RGQSFSVWIL CEAHCLKVAV DGQHLFEYYH RLRNLPTINR LEVGGDIQLT HVQT (1-323 aa encoded by BC110340)

Target Information

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Isothiocyanates attenuate immune checkpoint blockage therapy in gastric cancer via induction of PD-L1 expression.

The Journal of nutritional biochemistry

Zhang Q,Cao W,Yang C,Hong L,Geng S,Han H,Zhong C

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy

Li E,Xu J,Chen Q,Zhang X,Xu X,Liang T

Wed Feb 01 00:00:00 UTC 2023

Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.

Viruses

Wang H,Peng W,Wang J,Zhang C,Zhao W,Ran Y,Yang X,Chen J,Li H

Thu Apr 20 00:00:00 UTC 2023

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

Frontiers in molecular neuroscience

Peng Q,Zhang G,Guo X,Dai L,Xiong M,Zhang Z,Chen L,Zhang Z

Sun Sep 08 00:00:00 UTC 2024

Prognostic Value and Biological Function of Galectins in Malignant Glioma.

Frontiers in oncology

Zhu H,Liu D,Cheng L,Liu J,Wang G,Li H,Zhang Y,Mi H,Zhang S,Shu K,Yu X

Sat Jul 16 00:00:00 UTC 2022

Prognostic Value and Biological Function of Galectins in Malignant Glioma.

Frontiers in oncology

Zhu H,Liu D,Cheng L,Liu J,Wang G,Li H,Zhang Y,Mi H,Zhang S,Shu K,Yu X

Sat Jul 16 00:00:00 UTC 2022

Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.

Frontiers in immunology

Li G,Huang R,Fan W,Wang D,Wu F,Zeng F,Yu M,Zhai Y,Chang Y,Pan C,Jiang T,Yan W,Wang H,Zhang W

Fri Feb 11 00:00:00 UTC 2022

Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.

Frontiers in immunology

Li G,Huang R,Fan W,Wang D,Wu F,Zeng F,Yu M,Zhai Y,Chang Y,Pan C,Jiang T,Yan W,Wang H,Zhang W

Fri Feb 11 00:00:00 UTC 2022

Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.

Cell & bioscience

Qin A,Zhong T,Zou H,Wan X,Yao B,Zheng X,Yin D

Thu Mar 31 00:00:00 UTC 2022

Critical role of Tim-3 mediated autophagy in chronic stress induced immunosuppression.

Cell & bioscience

Qin A,Zhong T,Zou H,Wan X,Yao B,Zheng X,Yin D

Thu Mar 31 00:00:00 UTC 2022

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.

Stem cell research & therapy

Fan J,Tang X,Wang Q,Zhang Z,Wu S,Li W,Liu S,Yao G,Chen H,Sun L

Mon Sep 17 00:00:00 UTC 2018

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.

Stem cell research & therapy

Fan J,Tang X,Wang Q,Zhang Z,Wu S,Li W,Liu S,Yao G,Chen H,Sun L

Mon Sep 17 00:00:00 UTC 2018

Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer.

International journal of oncology

Yang J,Zhu L,Cai Y,Suo J,Jin J

Mon Sep 01 00:00:00 UTC 2014

Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer.

International journal of oncology

Yang J,Zhu L,Cai Y,Suo J,Jin J

Mon Sep 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactose binding, soluble 5; lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; urate transporter/channel protein

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Gene Aliases: AA407335; AI194909; AI265545; gal-9; galectin-9; HUAT; LGALS35; Lgals5; LGALS9; LGALS9A

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UniProt ID: (Human) O00182, (Mouse) O08573

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Entrez Gene ID: (Human) 3965, (Mouse) 16859

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signal transducer activity galactose binding enzyme binding carbohydrate binding disaccharide binding galactoside binding

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules natural killer cell tolerance induction chemotaxis inflammatory response female pregnancy positive regulation of gene expression negative regulation of gene expression response to lipopolysaccharide regulation of interleukin-4 production regulation of interleukin-5 production negative regulation of chemokine production negative regulation of interferon-gamma production negative regulation of tumor necrosis factor production positive regulation of interleukin-4 production positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway p38MAPK cascade positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of mast cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of activated T cell proliferation positive regulation of viral entry into host cell positive regulation of interleukin-1 beta secretion positive regulation of NF-kappaB transcription factor activity maternal process involved in female pregnancy positive regulation of activated T cell autonomous cell death ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade response to interleukin-1 cellular response to interferon-gamma positive regulation of transforming growth factor beta production positive regulation of monocyte chemotactic protein-1 production mature conventional dendritic cell differentiation cellular response to virus regulation of p38MAPK cascade positive regulation of interferon-gamma secretion positive regulation of tumor necrosis factor secretion positive regulation of interleukin-8 secretion positive regulation of dendritic cell chemotaxis negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of interleukin-13 secretion positive regulation of dendritic cell apoptotic process positive regulation of interleukin-6 secretion positive regulation of interleukin-10 secretion positive regulation of interleukin-12 secretion positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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