Product References
CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis.
Molecular cell
Ratnayeke N,Baris Y,Chung M,Yeeles JTP,Meyer T
Thu Jan 05 00:00:00 UTC 2023
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Nature communications
Gao Y,Guitton-Sert L,Dessapt J,Coulombe Y,Rodrigue A,Milano L,Blondeau A,Larsen NB,Duxin JP,Hussein S,Fradet-Turcotte A,Masson JY
Tue Jan 24 00:00:00 UTC 2023
Human Metastatic Cholangiocarcinoma Patient-Derived Xenografts and Tumoroids for Preclinical Drug Evaluation.
Clinical cancer research : an official journal of the American Association for Cancer Research
Serra-Camprubí Q,Verdaguer H,Oliveros W,Lupión-Garcia N,Llop-Guevara A,Molina C,Vila-Casadesús M,Turpin A,Neuzillet C,Frigola J,Querol J,Yáñez-Bartolomé M,Castet F,Fabregat-Franco C,Escudero-Iriarte C,Escorihuela M,Arenas EJ,Bernadó-Morales C,Haro N,Giles FJ,Pozo ÓJ,Miquel JM,Nuciforo PG,Vivancos A,Melé M,Serra V,Arribas J,Tabernero J,Peiró S,Macarulla T,Tian TV
Tue Jan 17 00:00:00 UTC 2023
Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.
Nature communications
Ter Brugge P,Moser SC,Bièche I,Kristel P,Ibadioune S,Eeckhoutte A,de Bruijn R,van der Burg E,Lutz C,Annunziato S,de Ruiter J,Masliah Planchon J,Vacher S,Courtois L,El-Botty R,Dahmani A,Montaudon E,Morisset L,Sourd L,Huguet L,Derrien H,Nemati F,Chateau-Joubert S,Larcher T,Salomon A,Decaudin D,Reyal F,Coussy F,Popova T,Wesseling J,Stern MH,Jonkers J,Marangoni E
Fri Apr 07 00:00:00 UTC 2023
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Nature communications
Xu X,Chang CW,Li M,Omabe K,Le N,Chen YH,Liang F,Liu Y
Sat Mar 04 00:00:00 UTC 2023
Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma.
Cancers
Capala ME,Pachler KS,Lauwers I,de Korte MA,Verkaik NS,Mast H,Jonker BP,Sewnaik A,Hardillo JA,Keereweer S,Monserez D,Koljenovic S,Mostert B,Verduijn GM,Petit S,van Gent DC
Thu Jan 12 00:00:00 UTC 2023
A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.
Cancer cell
Hutten SJ,de Bruijn R,Lutz C,Badoux M,Eijkman T,Chao X,Ciwinska M,Sheinman M,Messal H,Herencia-Ropero A,Kristel P,Mulder L,van der Waal R,Sanders J,Almekinders MM,Llop-Guevara A,Davies HR,van Haren MJ,Martin NI,Behbod F,Nik-Zainal S,Serra V,van Rheenen J,Lips EH,Wessels LFA,Wesseling J,Scheele CLGJ,Jonkers J
Mon May 08 00:00:00 UTC 2023
Nuclear pCHK1 as a potential biomarker of increased sensitivity to ATR inhibition.
The Journal of pathology
Sundararajan V,Tan TZ,Lim D,Peng Y,Wengner AM,Ngoi NYL,Jeyasekharan AD,Tan DSP
Wed Feb 01 00:00:00 UTC 2023
A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells.
Frontiers in oncology
Köcher S,Zech HB,Krug L,Gatzemeier F,Christiansen S,Meyer F,Rietow R,Struve N,Mansour WY,Kriegs M,Petersen C,Betz C,Rothkamm K,Rieckmann T
Sat Jul 16 00:00:00 UTC 2022
Developing patient-derived organoids to predict PARP inhibitor response and explore resistance overcoming strategies in ovarian cancer.
Pharmacological research
Tao M,Sun F,Wang J,Wang Y,Zhu H,Chen M,Liu L,Liu L,Lin H,Wu X
Sun May 01 00:00:00 UTC 2022
Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-AThr288-geminin dual signaling pathways.
Frontiers in pharmacology
Zhao H,Jia P,Nanding K,Wu M,Bai X,Morigen M,Fan L
Tue Sep 10 00:00:00 UTC 2024
Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities.
Neuro-oncology advances
Struve N,Hoffer K,Weik AS,Riepen B,Krug L,Cetin MH,Burmester J,Ott L,Liebing J,Gatzemeier F,Müller-Goebel J,Gerbach M,Bußmann L,Parplys AC,Unger K,Mansour WY,Schüller U,Rieckmann T,Petersen C,Rothkamm K,Short SC,Kriegs M
Mon Mar 14 00:00:00 UTC 2022
The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population.
Cancers
Alenezi WM,Milano L,Fierheller CT,Serruya C,Revil T,Oros KK,Behl S,Arcand SL,Nayar P,Spiegelman D,Gravel S,Mes-Masson AM,Provencher D,Foulkes WD,El Haffaf Z,Rouleau G,Bouchard L,Greenwood CMT,Masson JY,Ragoussis J,Tonin PN
Sat Apr 30 00:00:00 UTC 2022
Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification.
Cancer research
Pellegrino B,Herencia-Ropero A,Llop-Guevara A,Pedretti F,Moles-Fernández A,Viaplana C,Villacampa G,Guzmán M,Rodríguez O,Grueso J,Jiménez J,Arenas EJ,Degasperi A,Dias JML,Forment JV,O'Connor MJ,Déas O,Cairo S,Zhou Y,Musolino A,Caldas C,Nik-Zainal S,Clarke RB,Nuciforo P,Díez O,Serres-Créixams X,Peg V,Espinosa-Bravo M,Macarulla T,Oaknin A,Mateo J,Arribas J,Dienstmann R,Bellet M,Oliveira M,Saura C,Gutiérrez-Enríquez S,Balmaña J,Serra V
Fri Apr 15 00:00:00 UTC 2022
Basal expression of RAD51 foci predicts olaparib response in patient-derived ovarian cancer xenografts.
British journal of cancer
Guffanti F,Alvisi MF,Anastasia A,Ricci F,Chiappa M,Llop-Guevara A,Serra V,Fruscio R,Degasperi A,Nik-Zainal S,Bani MR,Lupia M,Giavazzi R,Rulli E,Damia G
Sat Jan 01 00:00:00 UTC 2022
Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer.
Science advances
Stanzione M,Zhong J,Wong E,LaSalle TJ,Wise JF,Simoneau A,Myers DT,Phat S,Sade-Feldman M,Lawrence MS,Hadden MK,Zou L,Farago AF,Dyson NJ,Drapkin BJ
Fri May 13 00:00:00 UTC 2022
IKKε Inhibitor Amlexanox Promotes Olaparib Sensitivity through the C/EBP-β-Mediated Transcription of Rad51 in Castrate-Resistant Prostate Cancer.
Cancers
Gilbert S,Péant B,Mes-Masson AM,Saad F
Thu Jul 28 00:00:00 UTC 2022
A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture.
Cancer research
Chakrabarty S,Quiros-Solano WF,Kuijten MMP,Haspels B,Mallya S,Lo CSY,Othman A,Silvestri C,van de Stolpe A,Gaio N,Odijk H,van de Ven M,de Ridder CMA,van Weerden WM,Jonkers J,Dekker R,Taneja N,Kanaar R,van Gent DC
Tue Feb 01 00:00:00 UTC 2022
Association of RAD51 with homologous recombination deficiency (HRD) and clinical outcomes in untreated triple-negative breast cancer (TNBC): analysis of the GeparSixto randomized clinical trial.
Annals of oncology : official journal of the European Society for Medical Oncology
Llop-Guevara A,Loibl S,Villacampa G,Vladimirova V,Schneeweiss A,Karn T,Zahm DM,Herencia-Ropero A,Jank P,van Mackelenbergh M,Fasching PA,Marmé F,Stickeler E,Schem C,Dienstmann R,Florian S,Nekljudova V,Balmaña J,Hahnen E,Denkert C,Serra V
Wed Dec 01 00:00:00 UTC 2021
The RAD51-FFPE Test; Calibration of a Functional Homologous Recombination Deficiency Test on Diagnostic Endometrial and Ovarian Tumor Blocks.
Cancers
van Wijk LM,Kramer CJH,Vermeulen S,Ter Haar NT,de Jonge MM,Kroep JR,de Kroon CD,Gaarenstroom KN,Vrieling H,Bosse T,Vreeswijk MPG
Tue Jun 15 00:00:00 UTC 2021
Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells.
Frontiers in oncology
Hintelmann K,Berenz T,Kriegs M,Christiansen S,Gatzemeier F,Struve N,Petersen C,Betz C,Rothkamm K,Oetting A,Rieckmann T
Sat Aug 07 00:00:00 UTC 2021
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity.
Proceedings of the National Academy of Sciences of the United States of America
Ippati S,Deng Y,van der Hoven J,Heu C,van Hummel A,Chua SW,Paric E,Chan G,Feiten A,Fath T,Ke YD,Haass NK,Ittner LM
Tue Mar 23 00:00:00 UTC 2021
Lysophosphatidic Acid-Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase.
Frontiers in pharmacology
Zhao H,Gezi G,Tian X,Jia P,Morigen M,Fan L
Fri Oct 22 00:00:00 UTC 2021
Lysophosphatidic Acid-Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase.
Frontiers in pharmacology
Zhao H,Gezi G,Tian X,Jia P,Morigen M,Fan L
Fri Oct 22 00:00:00 UTC 2021
Clinical consequences of BRCA2 hypomorphism.
NPJ breast cancer
Castells-Roca L,Gutiérrez-Enríquez S,Bonache S,Bogliolo M,Carrasco E,Aza-Carmona M,Montalban G,Muñoz-Subirana N,Pujol R,Cruz C,Llop-Guevara A,Ramírez MJ,Saura C,Lasa A,Serra V,Diez O,Balmaña J,Surrallés J
Thu Sep 09 00:00:00 UTC 2021
Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial.
Cancer discovery
Carreira S,Porta N,Arce-Gallego S,Seed G,Llop-Guevara A,Bianchini D,Rescigno P,Paschalis A,Bertan C,Baker C,Goodall J,Miranda S,Riisnaes R,Figueiredo I,Ferreira A,Pereira R,Crespo M,Gurel B,Nava Rodrigues D,Pettitt SJ,Yuan W,Serra V,Rekowski J,Lord CJ,Hall E,Mateo J,de Bono JS
Mon Nov 01 00:00:00 UTC 2021
The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas.
Cancers
van Wijk LM,Vermeulen S,Meijers M,van Diest MF,Ter Haar NT,de Jonge MM,Solleveld-Westerink N,van Wezel T,van Gent DC,Kroep JR,Bosse T,Gaarenstroom KN,Vrieling H,Vreeswijk MPG
Tue Sep 29 00:00:00 UTC 2020
Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway.
Life science alliance
Gerakopoulos V,Ngo P,Tsiokas L
Tue Sep 01 00:00:00 UTC 2020
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Nature communications
Rother MB,Pellegrino S,Smith R,Gatti M,Meisenberg C,Wiegant WW,Luijsterburg MS,Imhof R,Downs JA,Vertegaal ACO,Huet S,Altmeyer M,van Attikum H
Fri Nov 13 00:00:00 UTC 2020
RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers.
Cancer research
Krais JJ,Wang Y,Bernhardy AJ,Clausen E,Miller JA,Cai KQ,Scott CL,Johnson N
Wed Jul 01 00:00:00 UTC 2020
Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Rein ID,Notø HØ,Bostad M,Huse K,Stokke T
Sat Aug 01 00:00:00 UTC 2020
BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers.
Science translational medicine
Coussy F,El-Botty R,Château-Joubert S,Dahmani A,Montaudon E,Leboucher S,Morisset L,Painsec P,Sourd L,Huguet L,Nemati F,Servely JL,Larcher T,Vacher S,Briaux A,Reyes C,La Rosa P,Lucotte G,Popova T,Foidart P,Sounni NE,Noel A,Decaudin D,Fuhrmann L,Salomon A,Reyal F,Mueller C,Ter Brugge P,Jonkers J,Poupon MF,Stern MH,Bièche I,Pommier Y,Marangoni E
Wed Feb 19 00:00:00 UTC 2020
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer.
Nature communications
Chopra N,Tovey H,Pearson A,Cutts R,Toms C,Proszek P,Hubank M,Dowsett M,Dodson A,Daley F,Kriplani D,Gevensleben H,Davies HR,Degasperi A,Roylance R,Chan S,Tutt A,Skene A,Evans A,Bliss JM,Nik-Zainal S,Turner NC
Fri May 29 00:00:00 UTC 2020
HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Cell reports
Brandsma I,Sato K,van Rossum-Fikkert SE,van Vliet N,Sleddens E,Reuter M,Odijk H,van den Tempel N,Dekkers DHW,Bezstarosti K,Demmers JAA,Maas A,Lebbink J,Wyman C,Essers J,van Gent DC,Baarends WM,Knipscheer P,Kanaar R,Zelensky AN
Tue Jun 25 00:00:00 UTC 2019
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.
Nature medicine
Kopper O,de Witte CJ,Lõhmussaar K,Valle-Inclan JE,Hami N,Kester L,Balgobind AV,Korving J,Proost N,Begthel H,van Wijk LM,Revilla SA,Theeuwsen R,van de Ven M,van Roosmalen MJ,Ponsioen B,Ho VWH,Neel BG,Bosse T,Gaarenstroom KN,Vrieling H,Vreeswijk MPG,van Diest PJ,Witteveen PO,Jonges T,Bos JL,van Oudenaarden A,Zweemer RP,Snippert HJG,Kloosterman WP,Clevers H
Wed May 01 00:00:00 UTC 2019
Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status.
Cancers
Venneker S,Kruisselbrink AB,Briaire-de Bruijn IH,de Jong Y,van Wijnen AJ,Danen EHJ,Bovée JVMG
Mon Dec 02 00:00:00 UTC 2019
Immunohistochemical assessment of chromatin licensing and DNA replication factor 1, geminin, and γ-H2A.X in oral epithelial precursor lesions and squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Siril YJ,Kouketsu A,Oikawa M,Takahashi T,Kumamoto H
Fri Nov 01 00:00:00 UTC 2019
Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research
de Jonge MM,Auguste A,van Wijk LM,Schouten PC,Meijers M,Ter Haar NT,Smit VTHBM,Nout RA,Glaire MA,Church DN,Vrieling H,Job B,Boursin Y,de Kroon CD,Rouleau E,Leary A,Vreeswijk MPG,Bosse T
Fri Feb 01 00:00:00 UTC 2019
A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.
EMBO molecular medicine
Castroviejo-Bermejo M,Cruz C,Llop-Guevara A,Gutiérrez-Enríquez S,Ducy M,Ibrahim YH,Gris-Oliver A,Pellegrino B,Bruna A,Guzmán M,Rodríguez O,Grueso J,Bonache S,Moles-Fernández A,Villacampa G,Viaplana C,Gómez P,Vidal M,Peg V,Serres-Créixams X,Dellaire G,Simard J,Nuciforo P,Rubio IT,Dienstmann R,Barrett JC,Caldas C,Baselga J,Saura C,Cortés J,Déas O,Jonkers J,Masson JY,Cairo S,Judde JG,O'Connor MJ,Díez O,Balmaña J,Serra V
Sat Dec 01 00:00:00 UTC 2018
A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.
EMBO molecular medicine
Castroviejo-Bermejo M,Cruz C,Llop-Guevara A,Gutiérrez-Enríquez S,Ducy M,Ibrahim YH,Gris-Oliver A,Pellegrino B,Bruna A,Guzmán M,Rodríguez O,Grueso J,Bonache S,Moles-Fernández A,Villacampa G,Viaplana C,Gómez P,Vidal M,Peg V,Serres-Créixams X,Dellaire G,Simard J,Nuciforo P,Rubio IT,Dienstmann R,Barrett JC,Caldas C,Baselga J,Saura C,Cortés J,Déas O,Jonkers J,Masson JY,Cairo S,Judde JG,O'Connor MJ,Díez O,Balmaña J,Serra V
Sat Dec 01 00:00:00 UTC 2018
Ex vivo assays to predict enhanced chemosensitization by hyperthermia in urothelial cancer of the bladder.
PloS one
van den Tempel N,Naipal KAT,Raams A,van Gent DC,Franckena M,Boormans JL,Kanaar R
Mon May 13 00:00:00 UTC 2019
Ex vivo assays to predict enhanced chemosensitization by hyperthermia in urothelial cancer of the bladder.
PloS one
van den Tempel N,Naipal KAT,Raams A,van Gent DC,Franckena M,Boormans JL,Kanaar R
Mon May 13 00:00:00 UTC 2019
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Cell reports
Nacson J,Krais JJ,Bernhardy AJ,Clausen E,Feng W,Wang Y,Nicolas E,Cai KQ,Tricarico R,Hua X,DiMarcantonio D,Martinez E,Zong D,Handorf EA,Bellacosa A,Testa JR,Nussenzweig A,Gupta GP,Sykes SM,Johnson N
Tue Sep 25 00:00:00 UTC 2018
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Cell reports
Nacson J,Krais JJ,Bernhardy AJ,Clausen E,Feng W,Wang Y,Nicolas E,Cai KQ,Tricarico R,Hua X,DiMarcantonio D,Martinez E,Zong D,Handorf EA,Bellacosa A,Testa JR,Nussenzweig A,Gupta GP,Sykes SM,Johnson N
Tue Sep 25 00:00:00 UTC 2018
Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines.
Oncotarget
Fleury H,Carmona E,Morin VG,Meunier L,Masson JY,Tonin PN,Provencher D,Mes-Masson AM
Tue Jun 20 00:00:00 UTC 2017
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.
Cancer research
Wang Y,Bernhardy AJ,Cruz C,Krais JJ,Nacson J,Nicolas E,Peri S,van der Gulden H,van der Heijden I,O'Brien SW,Zhang Y,Harrell MI,Johnson SF,Candido Dos Reis FJ,Pharoah PD,Karlan B,Gourley C,Lambrechts D,Chenevix-Trench G,Olsson H,Benitez JJ,Greene MH,Gore M,Nussbaum R,Sadetzki S,Gayther SA,Kjaer SK,D'Andrea AD,Shapiro GI,Wiest DL,Connolly DC,Daly MB,Swisher EM,Bouwman P,Jonkers J,Balmaña J,Serra V,Johnson N
Sun May 01 00:00:00 UTC 2016
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.
Cancer research
Wang Y,Bernhardy AJ,Cruz C,Krais JJ,Nacson J,Nicolas E,Peri S,van der Gulden H,van der Heijden I,O'Brien SW,Zhang Y,Harrell MI,Johnson SF,Candido Dos Reis FJ,Pharoah PD,Karlan B,Gourley C,Lambrechts D,Chenevix-Trench G,Olsson H,Benitez JJ,Greene MH,Gore M,Nussbaum R,Sadetzki S,Gayther SA,Kjaer SK,D'Andrea AD,Shapiro GI,Wiest DL,Connolly DC,Daly MB,Swisher EM,Bouwman P,Jonkers J,Balmaña J,Serra V,Johnson N
Sun May 01 00:00:00 UTC 2016
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.
Cancer research
Wang Y,Bernhardy AJ,Cruz C,Krais JJ,Nacson J,Nicolas E,Peri S,van der Gulden H,van der Heijden I,O'Brien SW,Zhang Y,Harrell MI,Johnson SF,Candido Dos Reis FJ,Pharoah PD,Karlan B,Gourley C,Lambrechts D,Chenevix-Trench G,Olsson H,Benitez JJ,Greene MH,Gore M,Nussbaum R,Sadetzki S,Gayther SA,Kjaer SK,D'Andrea AD,Shapiro GI,Wiest DL,Connolly DC,Daly MB,Swisher EM,Bouwman P,Jonkers J,Balmaña J,Serra V,Johnson N
Sun May 01 00:00:00 UTC 2016
Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest.
Cancer research
Schaaf L,Schwab M,Ulmer C,Heine S,Mürdter TE,Schmid JO,Sauer G,Aulitzky WE,van der Kuip H
Sun May 15 00:00:00 UTC 2016
Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest.
Cancer research
Schaaf L,Schwab M,Ulmer C,Heine S,Mürdter TE,Schmid JO,Sauer G,Aulitzky WE,van der Kuip H
Sun May 15 00:00:00 UTC 2016
Delayed DNA double-strand break repair following platin-based chemotherapy predicts treatment response in head and neck squamous cell carcinoma.
British journal of cancer
Bhide SA,Thway K,Lee J,Wong K,Clarke P,Newbold KL,Nutting CM,Harrington KJ
Tue Sep 27 00:00:00 UTC 2016
Delayed DNA double-strand break repair following platin-based chemotherapy predicts treatment response in head and neck squamous cell carcinoma.
British journal of cancer
Bhide SA,Thway K,Lee J,Wong K,Clarke P,Newbold KL,Nutting CM,Harrington KJ
Tue Sep 27 00:00:00 UTC 2016
In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies.
Theranostics
Chatalic KL,Konijnenberg M,Nonnekens J,de Blois E,Hoeben S,de Ridder C,Brunel L,Fehrentz JA,Martinez J,van Gent DC,Nock BA,Maina T,van Weerden WM,de Jong M
Thu Oct 06 00:00:00 UTC 2016
In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies.
Theranostics
Chatalic KL,Konijnenberg M,Nonnekens J,de Blois E,Hoeben S,de Ridder C,Brunel L,Fehrentz JA,Martinez J,van Gent DC,Nock BA,Maina T,van Weerden WM,de Jong M
Thu Oct 06 00:00:00 UTC 2016
APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.
Scientific reports
Zhang M,Yao F,Luan H,Zhao W,Jing T,Zhang S,Hou L,Zou X
Mon Dec 19 00:00:00 UTC 2016
APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.
Scientific reports
Zhang M,Yao F,Luan H,Zhao W,Jing T,Zhang S,Hou L,Zou X
Mon Dec 19 00:00:00 UTC 2016
Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.
PloS one
Cheng F,Twardowski L,Reifenberg K,Winter K,Canisius A,Pross E,Fan J,Schmitt E,Shultz LD,Lackner KJ,Torzewski M
Tue Aug 08 00:00:00 UTC 2017
Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.
PloS one
Cheng F,Twardowski L,Reifenberg K,Winter K,Canisius A,Pross E,Fan J,Schmitt E,Shultz LD,Lackner KJ,Torzewski M
Tue Aug 08 00:00:00 UTC 2017
Whole genomes redefine the mutational landscape of pancreatic cancer.
Nature
Waddell N,Pajic M,Patch AM,Chang DK,Kassahn KS,Bailey P,Johns AL,Miller D,Nones K,Quek K,Quinn MC,Robertson AJ,Fadlullah MZ,Bruxner TJ,Christ AN,Harliwong I,Idrisoglu S,Manning S,Nourse C,Nourbakhsh E,Wani S,Wilson PJ,Markham E,Cloonan N,Anderson MJ,Fink JL,Holmes O,Kazakoff SH,Leonard C,Newell F,Poudel B,Song S,Taylor D,Waddell N,Wood S,Xu Q,Wu J,Pinese M,Cowley MJ,Lee HC,Jones MD,Nagrial AM,Humphris J,Chantrill LA,Chin V,Steinmann AM,Mawson A,Humphrey ES,Colvin EK,Chou A,Scarlett CJ,Pinho AV,Giry-Laterriere M,Rooman I,Samra JS,Kench JG,Pettitt JA,Merrett ND,Toon C,Epari K,Nguyen NQ,Barbour A,Zeps N,Jamieson NB,Graham JS,Niclou SP,Bjerkvig R,Grützmann R,Aust D,Hruban RH,Maitra A,Iacobuzio-Donahue CA,Wolfgang CL,Morgan RA,Lawlor RT,Corbo V,Bassi C,Falconi M,Zamboni G,Tortora G,Tempero MA,Gill AJ,Eshleman JR,Pilarsky C,Scarpa A,Musgrove EA,Pearson JV,Biankin AV,Grimmond SM
Thu Feb 26 00:00:00 UTC 2015
Whole genomes redefine the mutational landscape of pancreatic cancer.
Nature
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Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma.
Virchows Archiv : an international journal of pathology
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Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma.
Virchows Archiv : an international journal of pathology
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Medicine
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Cell cycle kinetic analysis of colorectal neoplasms using a new automated immunohistochemistry-based cell cycle detection method.
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Clinical cancer research : an official journal of the American Association for Cancer Research
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Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research
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A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
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Wed Dec 15 00:00:00 UTC 2010
A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
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Wed Dec 15 00:00:00 UTC 2010
