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Bioss
GluR1, GluR2 Polyclonal Antibody
Product Details
BS-10042R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GluR1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMPA 1; AMPA selective glutamate receptor; AMPA-selective glutamate receptor 1; AMPA-selective glutamate receptor 2; GluA1; GluR-1; GluR-2; GluR-A; GluR-B; GluR-K1; GluR-K2; GluR1; Glutamate receptor 1; Glutamate receptor 2; glutamate receptor A; glutamate receptor B; glutamate receptor B flip isoform; Glutamate receptor ionotropic, AMPA 1; Glutamate receptor ionotropic, AMPA 2; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA1 (alpha 1)
Gene Aliases: 2900051M01Rik; Glr-1; Glr1; GLUA1; GluA2; GLUH1; Glur-1; Glur-2; GluR-A; GluR-B; gluR-K1; GluR-K2; GLUR1; GLUR2; GLURA; GLURB; GRIA1; GRIA2; HBGR1; HBGR2; HIPA1
UniProt ID: (Human) P42261, (Human) P42262, (Rat) P19490, (Mouse) P23818, (Rat) P19491
Entrez Gene ID: (Human) 2890, (Human) 2891, (Rat) 50592, (Mouse) 14799, (Mouse) 14800, (Rat) 29627
AMPA glutamate receptor activity
excitatory extracellular ligand-gated ion channel activity
extracellular-glutamate-gated ion channel activity
protein binding
glutamate receptor activity
PDZ domain binding
ionotropic glutamate receptor activity
G-protein alpha-subunit binding
adenylate cyclase binding
protein kinase binding
protein domain specific binding
small GTPase binding
myosin V binding
G-protein beta-subunit binding
beta-2 adrenergic receptor binding
identical protein binding
protein homodimerization activity
protein kinase A binding
receptor activity
ion channel activity
kainate selective glutamate receptor activity
calcium channel regulator activity
signal transduction
chemical synaptic transmission
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
ER to Golgi vesicle-mediated transport
long-term memory
receptor internalization
COPII vesicle coating
long term synaptic depression
regulation of receptor recycling
response to toxic substance
response to lithium ion
response to organic cyclic compound
neuronal action potential
spinal cord development
response to estradiol
synaptic transmission, glutamatergic
response to cocaine
response to drug
response to peptide hormone
positive regulation of membrane potential
response to arsenic-containing substance
regulation of synaptic plasticity
modulation of synaptic transmission
positive regulation of synaptic transmission
response to electrical stimulus
response to fungicide
cellular response to amino acid stimulus
cellular response to dsRNA
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to organic cyclic compound
cellular response to amine stimulus
transport
ion transport
establishment of protein localization
protein tetramerization
regulation of synaptic transmission, glutamatergic
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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