Product References
Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss.
Cells
Qiao X,Yang Y,Zhao Y,Wu X,Zhang L,Cai X,Ji J,Boström KI,Yao Y
MA1-510 was used in Western Blot to identify a new potential approach to counteracting unwanted transitions of osteoblast lineage cells in glucocorticoid treatment and may provide a novel strategy for ameliorating glucocorticoid-induced bone loss.
Wed Oct 11 00:00:00 UTC 2023
Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss.
Cells
Qiao X,Yang Y,Zhao Y,Wu X,Zhang L,Cai X,Ji J,Boström KI,Yao Y
MA1-510 was used in Western Blot to identify a new potential approach to counteracting unwanted transitions of osteoblast lineage cells in glucocorticoid treatment and may provide a novel strategy for ameliorating glucocorticoid-induced bone loss.
Wed Oct 11 00:00:00 UTC 2023
Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss.
Cells
Qiao X,Yang Y,Zhao Y,Wu X,Zhang L,Cai X,Ji J,Boström KI,Yao Y
MA1-510 was used in Western Blot to identify a new potential approach to counteracting unwanted transitions of osteoblast lineage cells in glucocorticoid treatment and may provide a novel strategy for ameliorating glucocorticoid-induced bone loss.
Wed Oct 11 00:00:00 UTC 2023
Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain.
Frontiers in molecular neuroscience
Toh P,Seale LA,Berry MJ,Torres DJ
MA1-510 was used in Western Blotting to demonstrate that early life exposure to excess glucocorticoid levels can alter selenoprotein levels in the developing brain.
Mon Feb 12 00:00:00 UTC 2024
Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain.
Frontiers in molecular neuroscience
Toh P,Seale LA,Berry MJ,Torres DJ
MA1-510 was used in Western Blotting to demonstrate that early life exposure to excess glucocorticoid levels can alter selenoprotein levels in the developing brain.
Mon Feb 12 00:00:00 UTC 2024
Prolactin and glucocorticoid receptors in the prefrontal cortex are associated with anxiety-like behavior in prenatally stressed adolescent offspring rats.
Journal of neuroendocrinology
Yao D,Lu Y,Li L,Wang S,Mu Y,Ding C,Zhao J,Liu M,Xu M,Wu H,Dou C,Zhu Z,Li H
MA1-510 was used in Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot to study the roles of PRL, corticosterone (CORT), and their receptors in PS-induced anxiety-like behavior in dams and their offspring and investigate whether chewing during maternal stress could prevent PS-induced harmful consequences.
Sun Jan 01 00:00:00 UTC 2023
Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea.
iScience
Marchetta P,Eckert P,Lukowski R,Ruth P,Singer W,Rüttiger L,Knipper M
MA1-510 was used in Immunohistochemistry to imply that stress hormone-dependent functions of central MR/GR contribute to "precognitive" sound processing in the cochlea.
Fri Mar 18 00:00:00 UTC 2022
The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation.
Science advances
Rinaldi L,Fettweis G,Kim S,Garcia DA,Fujiwara S,Johnson TA,Tettey TT,Ozbun L,Pegoraro G,Puglia M,Blagoev B,Upadhyaya A,Stavreva DA,Hager GL
MA1-510 was used in ChIP assay to show that loss of cohesin markedly diminishes the concentration of TF molecules at specific nuclear confinement sites, increasing TF local concentration and promoting gene regulation.
Fri Apr 01 00:00:00 UTC 2022
Korean Red Ginseng Ameliorates Fatigue via Modulation of 5-HT and Corticosterone in a Sleep-Deprived Mouse Model.
Nutrients
Kang JY,Kim DY,Lee JS,Hwang SJ,Kim GH,Hyun SH,Son CG
MA1-510 was used in Western Blotting to demonstrate the anti-fatigue effects of KRG in an SD mouse model, indicating the clinical relevance of KRG.
Mon Sep 06 00:00:00 UTC 2021
ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus.
Arthritis & rheumatology (Hoboken, N.J.)
Yao J,Leng L,Fu W,Li J,Bronner C,Bucala R
MA1-510 was used in Flow cytometry/Cell sorting to suggest a mechanism for genetic variation of glucocorticoid-regulated MIF transcription, with implications for autoimmune disease severity and glucocorticoid responsiveness.
Fri Oct 01 00:00:00 UTC 2021
Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage.
Cell reports
Præstholm SM,Correia CM,Goitea VE,Siersbæk MS,Jørgensen M,Havelund JF,Pedersen TÅ,Færgeman NJ,Grøntved L
MA1-510 was used in ChIP assay to investigate the temporal hepatic expression of glucocorticoid receptor target genes in response to feeding.
Tue Nov 02 00:00:00 UTC 2021
Genome-wide binding potential and regulatory activity of the glucocorticoid receptor's monomeric and dimeric forms.
Nature communications
Johnson TA,Paakinaho V,Kim S,Hager GL,Presman DM
MA1-510 was used in ChIP Assay to show that impairing dimerization affects binding even to open chromatin.
Wed Mar 31 00:00:00 UTC 2021
Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins.
Journal of cell science
Mazaira GI,Echeverria PC,Galigniana MD
MA1-510 was used in Western Blotting to show that nuclear import of GR was impaired, whereas GR nuclear export was enhanced.
Tue Jun 16 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
MA1-510 was used in Western Blot, ChIP assay to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
MA1-510 was used in Western Blot, ChIP assay to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
MA1-510 was used in Western Blot, ChIP assay to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
MA1-510 was used in Western Blot, ChIP assay to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
MA1-510 was used in Western Blot, ChIP assay to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Chronic inflammatory pain alters alcohol-regulated frontocortical signaling and associations between alcohol drinking and thermal sensitivity.
Neurobiology of pain (Cambridge, Mass.)
Adrienne McGinn M,Edwards KN,Edwards S
MA1-510 was used in Western Blotting to determine relationships between thermal nociceptive sensitivity and alcohol drinking in male Wistar rats.
Fri Mar 29 00:00:00 UTC 2024
Chronic inflammatory pain alters alcohol-regulated frontocortical signaling and associations between alcohol drinking and thermal sensitivity.
Neurobiology of pain (Cambridge, Mass.)
Adrienne McGinn M,Edwards KN,Edwards S
MA1-510 was used in Western Blotting to determine relationships between thermal nociceptive sensitivity and alcohol drinking in male Wistar rats.
Fri Mar 29 00:00:00 UTC 2024
Sex differences in hypothalamic-pituitary-adrenal axis regulation after chronic unpredictable stress.
Brain and behavior
Palumbo MC,Dominguez S,Dong H
MA1-510 was used in Western Blotting to investigate the behavioral and biochemical responses of the HPA axis in C57BL/6 mice.
Wed Apr 01 00:00:00 UTC 2020
The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells.
Nucleic acids research
Ogara MF,Rodríguez-Seguí SA,Marini M,Nacht AS,Stortz M,Levi V,Presman DM,Vicent GP,Pecci A
MA1-510 was used in Immunoprecipitation to show progesterone receptor/glucocorticoid receptor positive breast cancer cell lines show progesterone receptor-dependent genomic regulation that can be interfered with by the glucocorticoid receptor.
Mon Nov 18 00:00:00 UTC 2019
The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells.
Nucleic acids research
Ogara MF,Rodríguez-Seguí SA,Marini M,Nacht AS,Stortz M,Levi V,Presman DM,Vicent GP,Pecci A
MA1-510 was used in Immunoprecipitation to show progesterone receptor/glucocorticoid receptor positive breast cancer cell lines show progesterone receptor-dependent genomic regulation that can be interfered with by the glucocorticoid receptor.
Mon Nov 18 00:00:00 UTC 2019
Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver.
PLoS biology
Kalvisa A,Siersbæk MS,Præstholm SM,Christensen LJL,Nielsen R,Stohr O,Vettorazzi S,Tuckermann J,White M,Mandrup S,Grøntved L
MA1-510 was used in Chromatin immunoprecipitation to uncover mechanisms controlling hepatic postprandial gene expression.
Sat Dec 01 00:00:00 UTC 2018
Developmental Lead Exposure and Prenatal Stress Result in Sex-Specific Reprograming of Adult Stress Physiology and Epigenetic Profiles in Brain.
Toxicological sciences : an official journal of the Society of Toxicology
Sobolewski M,Varma G,Adams B,Anderson DW,Schneider JS,Cory-Slechta DA
MA1-510 was used in Western Blotting to determine the effect of developmental Pb ± PS exposures on glucocorticoid-related epigenetic profiles in brain mesocorticolimbic regions.
Fri Jun 01 00:00:00 UTC 2018
Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action.
Immunity
Oh KS,Patel H,Gottschalk RA,Lee WS,Baek S,Fraser IDC,Hager GL,Sung MH
MA1-510 was used in Chromatin immunoprecipitation to characterise the effects of late glucocorticoid treatment, and elucidate the mechanism of action.
Tue Aug 15 00:00:00 UTC 2017
Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias.
JCI insight
Gauthier M,Chakraborty K,Oriss TB,Raundhal M,Das S,Chen J,Huff R,Sinha A,Fajt M,Ray P,Wenzel SE,Ray A
Published figure using Glucocorticoid Receptor monoclonal antibody (Product # MA1-510) in ChIP assay
Thu Jul 06 00:00:00 UTC 2017
Glucocorticoid Receptor Binding Induces Rapid and Prolonged Large-Scale Chromatin Decompaction at Multiple Target Loci.
Cell reports
Jubb AW,Boyle S,Hume DA,Bickmore WA
MA1-510 was used in Chromatin immunoprecipitation to demonstrate that glucocorticoid addition to mouse bone-marrow-derived macrophages produces very rapid chromatin unfolding at loci associated with glucocorticoid receptor binding.
Tue Dec 12 00:00:00 UTC 2017
Forkhead box A3 mediates glucocorticoid receptor function in adipose tissue.
Proceedings of the National Academy of Sciences of the United States of America
Ma X,Xu L,Mueller E
MA1-510 was used in ChIP assay and western blot to show how forkhead box A3 mediates glucocorticoid receptor function in adipose tissue
Tue Mar 22 00:00:00 UTC 2016
Maternal Separation Induces Orofacial Mechanical Allodynia in Adulthood.
Journal of dental research
Yasuda M,Shinoda M,Honda K,Fujita M,Kawata A,Nagashima H,Watanabe M,Shoji N,Takahashi O,Kimoto S,Iwata K
MA1510 was used in immunohistochemistry - frozen section to study the involvement of corticosterone in orofacial mechanical hypersensitivity induced by maternal separation
Thu Sep 01 00:00:00 UTC 2016
Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice.
Neuroscience letters
Demuyser T,Bentea E,Deneyer L,Albertini G,Massie A,Smolders I
MA1-510 was used in western blot to research induction of robust depressive-like behavior and reduced BDNF levels in mice due to a disruption of the HPA-axis through corticosterone-release pellets
Thu Jul 28 00:00:00 UTC 2016
Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment.
Proceedings of the National Academy of Sciences of the United States of America
Arango-Lievano M,Lambert WM,Bath KG,Garabedian MJ,Chao MV,Jeanneteau F
MA1-510 was used in ChIP assay to study the molecular mechanism underlying neurotrophic-priming of glucocorticoid receptor function
Tue Dec 22 00:00:00 UTC 2015
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.
Genome research
Stavreva DA,Coulon A,Baek S,Sung MH,John S,Stixova L,Tesikova M,Hakim O,Miranda T,Hawkins M,Stamatoyannopoulos JA,Chow CC,Hager GL
MA1-510 was used in ChIP assay to study the effect of pulsatile hormone stimulations on gene and regulatory element activation
Mon Jun 01 00:00:00 UTC 2015
Development and validation of an immunohistochemistry assay to assess glucocorticoid receptor expression for clinical trials of mifepristone in breast cancer.
Cancer management and research
Baker GM,Murphy T,Block T,Nguyen D,Lynch FJ
MA1-510 was used in immunohistochemistry - paraffin section to establish an immunohistochemistry assay to examine glucocorticoid receptor expression in human invasive breast carcinoma samples
Thu Dec 17 00:00:00 UTC 2015
Effects of maternal dexamethasone treatment early in pregnancy on glucocorticoid receptors in the ovine placenta.
Reproductive sciences (Thousand Oaks, Calif.)
Shang H,Meng W,Sloboda DM,Li S,Ehrlich L,Plagemann A,Dudenhausen JW,Henrich W,Newnham JP,Challis JR,Braun T
MA1-510 was used in immunohistochemistry and western blot to measure the expression of glucocorticoid receptors in pregnant ewes
Fri May 01 00:00:00 UTC 2015
Environmental enrichment mitigates the sex-specific effects of gestational inflammation on social engagement and the hypothalamic pituitary adrenal axis-feedback system.
Brain, behavior, and immunity
Connors EJ,Shaik AN,Migliore MM,Kentner AC
MA1-510 was used in western blot to study the effect of environment enrichment on maternal immune activation
Sat Nov 01 00:00:00 UTC 2014
A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction.
Biochemistry
Zhu R,Lu X,Pradhan M,Armstrong SP,Storchan GB,Chow CC,Simons SS
MA1-510 was used in western blot to study regulation of GR-mediated gene expression by Cdk9 independently of its kinase activity
Tue Mar 25 00:00:00 UTC 2014
ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.
Nature
Zhang L,Prak L,Rayon-Estrada V,Thiru P,Flygare J,Lim B,Lodish HF
MA1-510 was used in ChIP assay to study the role of the ZFP36L RNA binding protein in glucocorticoid-induced early burst-forming unit-erythroid progenitor self-renewal
Thu Jul 04 00:00:00 UTC 2013
Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation.
Molecular and cellular biology
Lambert WM,Xu CF,Neubert TA,Chao MV,Garabedian MJ,Jeanneteau FD
MA1-510 was used in ChIP assay to study the role of glucocorticoid receptor phosphorylation in the mechanism by which BDNF modulates the glucocorticoid transcriptome
Sun Sep 01 00:00:00 UTC 2013
Brain region- and sex-specific modulation of mitochondrial glucocorticoid receptor phosphorylation in fluoxetine treated stressed rats: effects on energy metabolism.
Psychoneuroendocrinology
Adzic M,Lukic I,Mitic M,Djordjevic J,Elaković I,Djordjevic A,Krstic-Demonacos M,Matić G,Radojcic M
MA1-510 was used in western blot to study the influence of gender on the effects of fluoxetine treatment on mitochondrial glucocortocoid receptor phosphorylation in different brain regions of stressed rats
Sun Dec 01 00:00:00 UTC 2013
Corticosterone modulates fear responses and the expression of glucocorticoid receptors in the brain of high-anxiety rats.
Neuroscience letters
Wisłowska-Stanek A,Lehner M,Skórzewska A,Maciejak P,Szyndler J,Turzyńska D,Sobolewska A,Płaźnik A
MA1-510 was used in immunohistochemistry to study the effect of corticosterone administration on glucocorticoid receptor expression and fear responses in high- and low-anxiety rats
Tue Jan 15 00:00:00 UTC 2013
Specificity in the actions of the UBR1 ubiquitin ligase in the degradation of nuclear receptors.
FEBS open bio
Sultana R,Theodoraki MA,Caplan AJ
MA1-510 was used in immunohistochemistry to study UBR1 ubiquitin ligase specificity in respect of the nuclear receptors it degrades
Tue Nov 19 00:00:00 UTC 2013
Regulation of hypothalamic corticotropin-releasing hormone transcription by elevated glucocorticoids.
Molecular endocrinology (Baltimore, Md.)
Evans AN,Liu Y,Macgregor R,Huang V,Aguilera G
MA1-510 was used in ChIP assay to study the mechanism by which elevated glucocorticoid levels transcriptionally regulate hypothalamic corticotropin-releasing hormone production
Fri Nov 01 00:00:00 UTC 2013
PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation.
The Journal of biological chemistry
Zhang Z,Sun Y,Cho YW,Chow CC,Simons SS
MA1-510 was used in ChIP assay to study the inhibition of glucocorticoid receptor transactivation by PA1
Fri Jan 04 00:00:00 UTC 2013
BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.
Proceedings of the National Academy of Sciences of the United States of America
Jeanneteau FD,Lambert WM,Ismaili N,Bath KG,Lee FS,Garabedian MJ,Chao MV
MA1-510 was used in immunoprecipitation to investigate the effect of BDNF and glucocorticoids on CRH regulation in the hypothalamus
Tue Jan 24 00:00:00 UTC 2012
Expression and regulation of human fetal-specific CYP3A7 in mice.
Endocrinology
Pang XY,Cheng J,Kim JH,Matsubara T,Krausz KW,Gonzalez FJ
MA1-510 was used in immunoprecipitation to investigate the expression of CYP3A7 and its regulation mechanism in fetal liver
Thu Mar 01 00:00:00 UTC 2012
Enhanced stimulus sequence-dependent repeated learning in male offspring after prenatal stress alone or in conjunction with lead exposure.
Neurotoxicology
Cory-Slechta DA,Virgolini MB,Liu S,Weston D
MA1-510 was used in western blot to study the effects of prenatal stress alone or in conjunction with lead exposure on learning in male offspring
Mon Oct 01 00:00:00 UTC 2012
Separate regions of glucocorticoid receptor, coactivator TIF2, and comodulator STAMP modify different parameters of glucocorticoid-mediated gene induction.
Molecular and cellular endocrinology
Awasthi S,Simons SS
MA1-510 was used in ChIP assay to study the role of different regions of the glucocorticid receptor in glucocorticoid-mediated gene expression
Tue May 15 00:00:00 UTC 2012
Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation.
The Journal of biological chemistry
Blackford JA,Guo C,Zhu R,Dougherty EJ,Chow CC,Simons SS
MA1-510 was used in western blot to use a novel competition assay to study the spatial and temporal binding of cofactors and reporter genes involved in steroid-regulated transactivation
Fri Nov 30 00:00:00 UTC 2012
Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism.
Cell
Voss TC,Schiltz RL,Sung MH,Yen PM,Stamatoyannopoulos JA,Biddie SC,Johnson TA,Miranda TB,John S,Hager GL
MA1-510 was used in immunoprecipitation to investigate the mechanism for the chromatin remodeling by transcription factor-DNA interactions
Fri Aug 19 00:00:00 UTC 2011
Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism.
Cell
Voss TC,Schiltz RL,Sung MH,Yen PM,Stamatoyannopoulos JA,Biddie SC,Johnson TA,Miranda TB,John S,Hager GL
MA1-510 was used in immunoprecipitation to investigate the mechanism for the chromatin remodeling by transcription factor-DNA interactions
Fri Aug 19 00:00:00 UTC 2011
Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.
Nature genetics
John S,Sabo PJ,Thurman RE,Sung MH,Biddie SC,Johnson TA,Hager GL,Stamatoyannopoulos JA
MA1-510 was used in immunoprecipitation to investigate the effect of chromatin structure on glucocorticoid receptor binding
Tue Mar 01 00:00:00 UTC 2011
Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.
The EMBO journal
Siersbæk R,Nielsen R,John S,Sung MH,Baek S,Loft A,Hager GL,Mandrup S
MA1-510 was used in ChIP assay to investigate the changes of chromatin structure in early adipogenesis
Wed Apr 20 00:00:00 UTC 2011
DNA methylation status predicts cell type-specific enhancer activity.
The EMBO journal
Wiench M,John S,Baek S,Johnson TA,Sung MH,Escobar T,Simmons CA,Pearce KH,Biddie SC,Sabo PJ,Thurman RE,Stamatoyannopoulos JA,Hager GL
MA1-510 was used in ChIP assay to study the effect of DNA methylation on cell type-specific enhancer activity
Fri Jun 24 00:00:00 UTC 2011
Interactions of lifetime lead exposure and stress: behavioral, neurochemical and HPA axis effects.
Neurotoxicology
Rossi-George A,Virgolini MB,Weston D,Thiruchelvam M,Cory-Slechta DA
MA1-510 was used in western blot to study how environmental exposure to lead interacts with stress.
Sat Jan 01 00:00:00 UTC 2011
Expression of human glucocorticoid receptor in T lymphocytes in acute-on-chronic hepatitis B liver failure.
Digestive diseases and sciences
Gao L,Wang JF,Xiang M,Fan YC,Zhang ZG,Wang K
MA1-510 was used in flow cytometry to identify the role of the glucocorticoid receptor in liver failure by hepatitis B
Thu Sep 01 00:00:00 UTC 2011
Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats.
The Journal of nutritional biochemistry
Kawabata K,Kawai Y,Terao J
MA1-510 was used in western blot to investigate the influence of quercetin on the activation of hypothalamic-pituitary-adrenal axis caused by water immersion-restraint in rats
Sat May 01 00:00:00 UTC 2010
Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth.
Journal of neurochemistry
Quintá HR,Maschi D,Gomez-Sanchez C,Piwien-Pilipuk G,Galigniana MD
MA1-510 was used in western blot to investigate the alterations hsp90-binding immunophilins distribution during neuronal growth and differentiation
Mon Nov 01 00:00:00 UTC 2010
The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.
Molecular and cellular biology
Galigniana MD,Erlejman AG,Monte M,Gomez-Sanchez C,Piwien-Pilipuk G
MA1-510 was used in western blot to investigate the role of the heat shock protein 90-FKBP52 complex in the nucleus
Mon Mar 01 00:00:00 UTC 2010
Glucocorticoid-induced impairment of mammary gland involution is associated with STAT5 and STAT3 signaling modulation.
Endocrinology
Bertucci PY,Quaglino A,Pozzi AG,Kordon EC,Pecci A
MA1-510 was used in western blot to study the role of STAT3 and STAT5 in glucocorticoid-induced impairment of mammary gland involution.
Wed Dec 01 00:00:00 UTC 2010
Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response.
IUBMB life
Arambasić J,Poznanović G,Ivanović-Matić S,Bogojević D,Mihailović M,Uskoković A,Grigorov I
MA1-510 was used in immunoprecipitation to investigate the mechanism for the regulation of haptoglobin expression in rats during the acute phase response
Mon Mar 01 00:00:00 UTC 2010
HSD11B1, HSD11B2, PTGS2, and NR3C1 expression in the peri-implantation ovine uterus: effects of pregnancy, progesterone, and interferon tau.
Biology of reproduction
Simmons RM,Satterfield MC,Welsh TH,Bazer FW,Spencer TE
MA1-510 was used in immunohistochemistry to investigate the effects of pregnancy, progesterone, and interferon tau for HSD11B1, HSD11B2, PTGS2, and NR3C1 expression in the peri-implantation ovine uterus
Fri Jan 01 00:00:00 UTC 2010
Hsp110 chaperones control client fate determination in the hsp70-Hsp90 chaperone system.
Molecular biology of the cell
Mandal AK,Gibney PA,Nillegoda NB,Theodoraki MA,Caplan AJ,Morano KA
MA1-510 was used in immunoprecipitation to identify the role of Sse1 in chaperone-mediated protein folding and stability
Sat May 01 00:00:00 UTC 2010
Localization of mineralocorticoid receptors at mammalian synapses.
PloS one
Prager EM,Brielmaier J,Bergstrom HC,McGuire J,Johnson LR
MA1-510 was used in immunohistochemistry and western blot to show the presence of mineralocorticoid receptors in the amygdala synapses
Wed Dec 15 00:00:00 UTC 2010
Localization of mineralocorticoid receptors at mammalian synapses.
PloS one
Prager EM,Brielmaier J,Bergstrom HC,McGuire J,Johnson LR
MA1-510 was used in immunohistochemistry and western blot to show the presence of mineralocorticoid receptors in the amygdala synapses
Wed Dec 15 00:00:00 UTC 2010
Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
The Journal of biological chemistry
Wang AM,Morishima Y,Clapp KM,Peng HM,Pratt WB,Gestwicki JE,Osawa Y,Lieberman AP
MA1-510 was used in western blot to investigate the effect of methylene blue-induced HSP70 inhibition on protein functions and degradation
Fri May 21 00:00:00 UTC 2010
The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats.
The international journal of biochemistry & cell biology
Adzic M,Djordjevic A,Demonacos C,Krstic-Demonacos M,Radojcic MB
MA1-510 was used in western blot to study the mitochondrial dysfunction in neuroendocrine stresses and its mechanism
Sun Nov 01 00:00:00 UTC 2009
Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.
Neuroscience
Dong H,Yuede CM,Yoo HS,Martin MV,Deal C,Mace AG,Csernansky JG
MA1-510 was used in immunohistochemistry to investigate the role of corticosterone and related receptor in beta-amyloid plaques in Tg2576 mice
Thu Jul 31 00:00:00 UTC 2008
Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.
Neuroscience
Dong H,Yuede CM,Yoo HS,Martin MV,Deal C,Mace AG,Csernansky JG
MA1-510 was used in immunohistochemistry to investigate the role of corticosterone and related receptor in beta-amyloid plaques in Tg2576 mice
Thu Jul 31 00:00:00 UTC 2008
Farnesylation of Ydj1 is required for in vivo interaction with Hsp90 client proteins.
Molecular biology of the cell
Flom GA,Lemieszek M,Fortunato EA,Johnson JL
MA1-510 was used in western blot to study the in vivo interaction between Ydj1 and Hsp90 client proteins.
Mon Dec 01 00:00:00 UTC 2008
Interaction and functional interference of glucocorticoid receptor and SOCS1.
The Journal of biological chemistry
Haffner MC,Jurgeit A,Berlato C,Geley S,Parajuli N,Yoshimura A,Doppler W
MA1-510 was used in immunocytochemistry to study the interaction between the the glucocorticoid receptor and SOCS1
Fri Aug 08 00:00:00 UTC 2008
Betamethasone-related acute alterations of microtubule-associated proteins in the fetal sheep brain are reversible and independent of age during the last one-third of gestation.
American journal of obstetrics and gynecology
Antonow-Schlorke I,Müller T,Brodhun M,Wicher C,Schubert H,Nathanielsz PW,Witte OW,Schwab M
MA1-510 was used in immunohistochemistry to study the reversibility of neuronal cytoskeletal alterations induced by betamethasone in fetal sheep
Fri Jun 01 00:00:00 UTC 2007
Amino-terminal domain of TIF2 is involved in competing for corepressor binding to glucocorticoid and progesterone receptors.
Biochemistry
Wang D,Wang Q,Awasthi S,Simons SS
MA1-510 was used in western blot to investigate TIF2 regions involved in the interaction of coactivators and corepressors with glucocorticoid and progesterone receptors
Tue Jul 10 00:00:00 UTC 2007
The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells.
Journal of neurochemistry
Morsink MC,Joëls M,Sarabdjitsingh RA,Meijer OC,De Kloet ER,Datson NA
MA1-510 was used in western blot to investigate the signalling transduction pathway initated by glucocorticoid receptor
Wed Nov 01 00:00:00 UTC 2006
The middle domain of Hsp90 acts as a discriminator between different types of client proteins.
Molecular and cellular biology
Hawle P,Siepmann M,Harst A,Siderius M,Reusch HP,Obermann WM
MA1-510 was used in western blot to investigate the differential roles of Hsp90 middle domain among different substrate targets.
Wed Nov 01 00:00:00 UTC 2006
Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes.
Endocrinology
Presman DM,Hoijman E,Ceballos NR,Galigniana MD,Pecci A
MA1-510 was used in immunocytochemistry, immunoprecipitation, and western blot to study the inhibition of glucocorticoid receptor nuclear translocation by melatonin in mouse thymocytes
Wed Nov 01 00:00:00 UTC 2006
Mechanism of action of Hic-5/androgen receptor activator 55, a LIM domain-containing nuclear receptor coactivator.
Molecular endocrinology (Baltimore, Md.)
Heitzer MD,DeFranco DB
MA1-510 was used in immunoprecipitation to demonstrate the role of Hic-5/androgen receptor activator 55 in glucocorticoid receptor-mediated gene expression.
Sun Jan 01 00:00:00 UTC 2006
TCR signaling inhibits glucocorticoid-induced apoptosis in murine thymocytes depending on the stage of development.
European journal of immunology
Erlacher M,Knoflach M,Stec IE,Böck G,Wick G,Wiegers GJ
MA1-510 was used in flow cytometry to study the role of TCR signaling in inhibiting glucocorticoid-induced apoptosis in murine thymocytes
Tue Nov 01 00:00:00 UTC 2005
Anthrax lethal toxin represses glucocorticoid receptor (GR) transactivation by inhibiting GR-DNA binding in vivo.
Molecular and cellular endocrinology
Webster JI,Sternberg EM
MA1-510 was used in immunohistochemistry to investigate the mechanism for the effect of anthrax lethal toxin on glucocorticoid receptor transactivation
Wed Sep 28 00:00:00 UTC 2005
Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function.
Toxicological sciences : an official journal of the Society of Toxicology
Virgolini MB,Chen K,Weston DD,Bauter MR,Cory-Slechta DA
MA1-510 was used in western blot to investigate the effect of lead exposure and intermittent stress on brain catecholamine systems
Sat Oct 01 00:00:00 UTC 2005
Glucocorticoid receptor ligand binding domain is sufficient for the modulation of glucocorticoid induction properties by homologous receptors, coactivator transcription intermediary factor 2, and Ubc9.
Molecular endocrinology (Baltimore, Md.)
Cho S,Kagan BL,Blackford JA,Szapary D,Simons SS
MA1-510 was used in western blot to determine the importance of the AF-1 and AF-2 domains for the regulatory activity of GRs, TIF2, and Ubc9.
Tue Feb 01 00:00:00 UTC 2005
Functional comparison of human and Drosophila Hop reveals novel role in steroid receptor maturation.
The Journal of biological chemistry
Carrigan PE,Riggs DL,Chinkers M,Smith DF
MA1-510 was used in western blot to compare the function of human and Drosophila Hop.
Fri Mar 11 00:00:00 UTC 2005
A Nuclear Receptor Atlas: macrophage activation.
Molecular endocrinology (Baltimore, Md.)
Barish GD,Downes M,Alaynick WA,Yu RT,Ocampo CB,Bookout AL,Mangelsdorf DJ,Evans RM
MA1-510 was used in western blot to study the dynamics of the macrophage activation process.
Sat Oct 01 00:00:00 UTC 2005
Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability.
Proceedings of the National Academy of Sciences of the United States of America
Wei Q,Lu XY,Liu L,Schafer G,Shieh KR,Burke S,Robinson TE,Watson SJ,Seasholtz AF,Akil H
MA1-510 was used in western blot to assess the effect of glucocorticoid receptor overexpression on emotional responsiveness
Tue Aug 10 00:00:00 UTC 2004
Effects of three courses of maternally administered dexamethasone at 0.7, 0.75, and 0.8 of gestation on prenatal and postnatal growth in sheep.
Pediatrics
Kutzler MA,Ruane EK,Coksaygan T,Vincent SE,Nathanielsz PW
MA1-510 was used in immunocytochemistry to investigate the effects of small amount of dexamethasone administered to pregnant sheep at different times of gestation
Sun Feb 01 00:00:00 UTC 2004
Corticosteroids but not pimecrolimus affect viability, maturation and immune function of murine epidermal Langerhans cells.
The Journal of investigative dermatology
Hoetzenecker W,Meingassner JG,Ecker R,Stingl G,Stuetz A,Elbe-Bürger A
MA1-510 was used in flow cytometry to evaluate the effects of corticosteroids and pimecrolimus on murine Langerhans cell survival, maturation, and immune function
Mon Mar 01 00:00:00 UTC 2004
Involvement of Bax protein in the prevention of glucocorticoid-induced thymocytes apoptosis by melatonin.
Endocrinology
Hoijman E,Rocha Viegas L,Keller Sarmiento MI,Rosenstein RE,Pecci A
MA1-510 was used in western blot to study the antiapoptotic effect of melatonin on glucocorticoid-treated thymocytes.
Thu Jan 01 00:00:00 UTC 2004
Mercury stimulates rat liver glucocorticoid receptor association with Hsp90 and Hsp70.
Journal of biochemical and molecular toxicology
Brkljacić J,Milutinović DV,Dundjerski J,Matić G
MA1-510 was used in western blot to investigate the effect of mercury on the assocation of heat shock proteins with glucocorticoid receptor
Tue May 24 00:00:00 UTC 2005
The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor.
Molecular endocrinology (Baltimore, Md.)
Nelson GM,Prapapanich V,Carrigan PE,Roberts PJ,Riggs DL,Smith DF
MA1-510 was used in western blot to study the effect of heat shock protein 70 cochaperone Hip on the glucocorticoid receptor maturation.
Thu Jul 01 00:00:00 UTC 2004
The role of hsp90 in heme-dependent activation of apo-neuronal nitric-oxide synthase.
The Journal of biological chemistry
Billecke SS,Draganov DI,Morishima Y,Murphy PJ,Dunbar AY,Pratt WB,Osawa Y
MA1-510 was used in western blot to study the mechanism for heme-dependent activation of apo-neuronal nitric-oxide synthase.
Fri Jul 16 00:00:00 UTC 2004
Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis.
Gut
Tjandra K,Le T,Swain MG
MA1-510 was used in western blot to investigate the expression of glucocorticoid receptors in T lymphocytes in a rat cholangitis.
Mon Sep 01 00:00:00 UTC 2003
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo.
The EMBO journal
Riggs DL,Roberts PJ,Chirillo SC,Cheung-Flynn J,Prapapanich V,Ratajczak T,Gaber R,Picard D,Smith DF
MA1-510 was used in immunocytochemistry to investigate the effect of FKBP52 on glucocorticoid signaling
Mon Mar 03 00:00:00 UTC 2003
The Group 3 LIM domain protein paxillin potentiates androgen receptor transactivation in prostate cancer cell lines.
Cancer research
Kasai M,Guerrero-Santoro J,Friedman R,Leman ES,Getzenberg RH,DeFranco DB
MA1-510 was used in western blot to study the effect of paxillin on androgen receptor in prostate cancer cell lines
Fri Aug 15 00:00:00 UTC 2003
Visualization and mechanism of assembly of a glucocorticoid receptor.Hsp70 complex that is primed for subsequent Hsp90-dependent opening of the steroid binding cleft.
The Journal of biological chemistry
Murphy PJ,Morishima Y,Chen H,Galigniana MD,Mansfield JF,Simons SS,Pratt WB
MA1-510 was used in western blot to study the assembly mechanism of a glucocorticoid receptor and Hsp70 complex.
Fri Sep 12 00:00:00 UTC 2003
Nuclear export of the glucocorticoid receptor is accelerated by cell fusion-dependent release of calreticulin.
The Journal of biological chemistry
Walther RF,Lamprecht C,Ridsdale A,Groulx I,Lee S,Lefebvre YA,Haché RJ
MA1-510 was used in western blot to investigate the role of calreticulin during the nuclear export of the glucocorticoid receptor.
Fri Sep 26 00:00:00 UTC 2003
CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins.
Molecular endocrinology (Baltimore, Md.)
Lambert JR,Nordeen SK
MA1-510 was used in ChIP assay to investigate the role of glucocorticoids and progestins for CBP recruitment and histone acetylation in differential gene induction
Sun Jun 01 00:00:00 UTC 2003
Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Brewer JA,Kanagawa O,Sleckman BP,Muglia LJ
MA1-510 was used in western blot to detect the expression of GR protein in wild-type, heterozygous, and GRko mice
Thu Aug 15 00:00:00 UTC 2002
All of the protein interactions that link steroid receptor.hsp90.immunophilin heterocomplexes to cytoplasmic dynein are common to plant and animal cells.
Biochemistry
Harrell JM,Kurek I,Breiman A,Radanyi C,Renoir JM,Pratt WB,Galigniana MD
MA1-510 was used in western blot to study the commonality of steroid-receptor-HSP90-immunophilin heterocomplex interactions with cytoplasmic dynein in plant and animal cells
Tue Apr 30 00:00:00 UTC 2002
Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly.
The Journal of biological chemistry
Kanelakis KC,Shewach DS,Pratt WB
MA1-510 was used in immunocytochemistry to study the lucocorticoid receptor.hsp90 heterocomplex assembly.
Fri Sep 13 00:00:00 UTC 2002
Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxidoprogesterone.
Biochimica et biophysica acta
Piwien-Pilipuk G,Kanelakis KC,Ghini AA,Lantos CP,Litwack G,Burton G,Galigniana MD
MA1-510 was used in immunoprecipitation to study the role of an essential lysine residue in determining the hormone specificity of the mineralcorticoid receptor
Wed Feb 13 00:00:00 UTC 2002
Hormone-induced nucleosome positioning in the MMTV promoter is reversible.
The EMBO journal
Belikov S,Gelius B,Wrange O
MA1-510 was used in western blot to study the mechanism for hormone-induced nucleosome positioning in the mouse mammary tumor virus promoter in Xenopus oocytes
Fri Jun 01 00:00:00 UTC 2001
Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins.
Proceedings of the National Academy of Sciences of the United States of America
Soubeyrand S,Torrance H,Giffin W,Gong W,Schild-Poulter C,Haché RJ
MA1-510 was used in immunoprecipitation to investigate the DNA-dependent protein kinase activation and autoregulation.
Tue Aug 14 00:00:00 UTC 2001
Differential interactions of specific nuclear factor I isoforms with the glucocorticoid receptor and STAT5 in the cooperative regulation of WAP gene transcription.
Molecular and cellular biology
Mukhopadhyay SS,Wyszomierski SL,Gronostajski RM,Rosen JM
MA1-510 was used in western blot to study the interaction of SNF1 isoforms with the glucocorticoid receptor and STAT5.
Mon Oct 01 00:00:00 UTC 2001
Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces.
Molecular and cellular biology
Savory JG,Préfontaine GG,Lamprecht C,Liao M,Walther RF,Lefebvre YA,Haché RJ
MA1-510 was used in immunocytochemistry to investigate the mechanism of glucocorticoid receptor homodimerization and glucocorticoid-mineralocorticoid receptor heterodimerization.
Thu Feb 01 00:00:00 UTC 2001
High neonatal leptin exposure enhances brain GR expression and feedback efficacy on the adrenocortical axis of developing rats.
Endocrinology
Proulx K,Clavel S,Nault G,Richard D,Walker CD
MA1-510 was used in western blot to study the effect of neonatal leptin exposure on brain glucocorticoid receptor expression.
Thu Nov 01 00:00:00 UTC 2001
Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1.
Molecular endocrinology (Baltimore, Md.)
Biola A,Lefebvre P,Perrin-Wolff M,Sturm M,Bertoglio J,Pallardy M
MA1-510 was used in immunoprecipitation to study the mechanism of glucocorticoid receptor transcriptional activity by interleukin-2.
Sun Jul 01 00:00:00 UTC 2001
Heterodimerization between the glucocorticoid receptor and the unrelated DNA-binding protein, Xenopus glucocorticoid receptor accessory factor.
Molecular endocrinology (Baltimore, Md.)
Morin B,Woodcock GR,Nichols LA,Holland LJ
MA1-510 was used in EMSA to study the interaction of xenopus glucocorticoid receptor accessory factor and glucocorticoid receptor.
Thu Mar 01 00:00:00 UTC 2001
Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor.
Molecular endocrinology (Baltimore, Md.)
Wyszomierski SL,Rosen JM
MA1-510 was used in western blot to study the effect of glucocorticoid receptor on beta-casein gene transcription.
Thu Feb 01 00:00:00 UTC 2001
Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.
The Journal of biological chemistry
Murphy PJ,Kanelakis KC,Galigniana MD,Morishima Y,Pratt WB
MA1-510 was used in western blot to demonstrate that the two chaperone proteins cooperate with each other to open up the steroid binding site.
Fri Aug 10 00:00:00 UTC 2001
A role for the Hsp40 Ydj1 in repression of basal steroid receptor activity in yeast.
Molecular and cellular biology
Johnson JL,Craig EA
MA1-510 was used in western blot to study the role of Hsp40 in repression of basal steroid receptor activity in yeast.
Mon May 01 00:00:00 UTC 2000
hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.
Biochemistry
Kanelakis KC,Murphy PJ,Galigniana MD,Morishima Y,Takayama S,Reed JC,Toft DO,Pratt WB
MA1-510 was used in western blot to study the posible involvement of Hip in glucocorticoid receptor-hsp90 heterocomplex assembly
Tue Nov 21 00:00:00 UTC 2000
The molecular chaperones Hsp90 and Hsc70 are both necessary and sufficient to activate hormone binding by glucocorticoid receptor.
The Journal of biological chemistry
Rajapandi T,Greene LE,Eisenberg E
MA1-510 was used in western blot to demonstrate the roles of Hsp90 and Hsc70 in glucocorticoid receptor-ligand binding.
Fri Jul 21 00:00:00 UTC 2000
The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system.
The Journal of biological chemistry
Morishima Y,Kanelakis KC,Silverstein AM,Dittmar KD,Estrada L,Pratt WB
MA1-510 was used in western blot to investigate the role of the Hsp organizer protein hop during the glucocorticoid receptor folding.
Fri Mar 10 00:00:00 UTC 2000
Early maturation of T-cell progenitors in the absence of glucocorticoids.
Blood
Sacedón R,Vicente A,Varas A,Jiménez E,Muñoz JJ,Zapata AG
MA1-510 was used in immunocytochemistry to investigate the important role of glucocorticoids in the early maturation of T-cell progenitors
Fri Oct 15 00:00:00 UTC 1999
Glucocorticoids downregulate cyclooxygenase-1 gene expression and prostacyclin synthesis in fetal pulmonary artery endothelium.
Circulation research
Jun SS,Chen Z,Pace MC,Shaul PW
MA1-510 was used in western blot to determine whether glucocorticoid receptor (GR) protein is expressed in the ovine fetal PAECs
Fri Feb 05 00:00:00 UTC 1999
Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51.
The Journal of clinical endocrinology and metabolism
Reynolds PD,Ruan Y,Smith DF,Scammell JG
MA1-510 was used in western blot to study the expression of the hsp90-associated immunophilin FKBP51 in squirrel monkeys and its effect on glucocorticoid receptor.
Mon Feb 01 00:00:00 UTC 1999
Glucocorticoid-mediated regulation of thymic dendritic cell function.
International immunology
Sacedón R,Vicente A,Varas A,Jiménez E,Muñoz JJ,Zapata AG
MA1-510 was used in immunocytochemistry to investigate the effect of glucocorticoids on the biological properties of thymic dendritic cells
Sun Aug 01 00:00:00 UTC 1999
Discrimination between NL1- and NL2-mediated nuclear localization of the glucocorticoid receptor.
Molecular and cellular biology
Savory JG,Hsu B,Laquian IR,Giffin W,Reich T,Haché RJ,Lefebvre YA
MA1-510 was used in immunocytochemistry to study the subcellular localization and nuclear import of the glucocorticoid receptor
Mon Feb 01 00:00:00 UTC 1999
Defense of adrenocorticosteroid receptor expression in rat hippocampus: effects of stress and strain.
Endocrinology
Herman JP,Watson SJ,Spencer RL
MA1-510 was used in western blot to study the modulation of the adrenocorticosteroid receptor expression in rat hippocampus
Wed Sep 01 00:00:00 UTC 1999
Regulation of growth hormone-releasing hormone receptor messenger ribonucleic acid expression by glucocorticoids in MtT-S cells and in the pituitary gland of fetal rats.
Endocrinology
Nogami H,Inoue K,Moriya H,Ishida A,Kobayashi S,Hisano S,Katayama M,Kawamura K
MA1-510 was used in immunocytochemistry to study the molecular mechanism of the regulation of GHRH-R gene expression
Tue Jun 01 00:00:00 UTC 1999
Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.
The Journal of biological chemistry
Kanelakis KC,Morishima Y,Dittmar KD,Galigniana MD,Takayama S,Reed JC,Pratt WB
MA1-510 was used in western blot to investigate the different roles of the hsp70-binding protein BAG-1 during glucocorticoid receptor folding
Fri Nov 26 00:00:00 UTC 1999
Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation.
Molecular endocrinology (Baltimore, Md.)
Wyszomierski SL,Yeh J,Rosen JM
MA1-510 was used in immunocytochemistry to investigate the synergistic regulation of transcription through the interaction between STAT5 and glucocorticoid receptor
Mon Feb 01 00:00:00 UTC 1999
The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element.
The Journal of biological chemistry
Chandran UR,Warren BS,Baumann CT,Hager GL,DeFranco DB
MA1-510 was used in EMSA assay to study the effect of the mutation of the distal nGRE at a consensus Oct-1 site
Fri Jan 22 00:00:00 UTC 1999
The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding.
The Journal of biological chemistry
Giannoukos G,Silverstein AM,Pratt WB,Simons SS
MA1-510 was used in western blot to investigate the role of the seven amino acids (547-553) of rat glucocorticoid receptor during the steroid and hsp90 binding
Fri Dec 17 00:00:00 UTC 1999
Inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton.
The Journal of biological chemistry
Galigniana MD,Housley PR,DeFranco DB,Pratt WB
MA1-510 was used in western blot to study the mechanism of the inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid
Fri Jun 04 00:00:00 UTC 1999
Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo.
The Journal of biological chemistry
Bender AT,Silverstein AM,Demady DR,Kanelakis KC,Noguchi S,Pratt WB,Osawa Y
MA1-510 was used in western blot to study the role of the Hsp90-based chaperone system during the neuronal nitric-oxide synthase
Fri Jan 15 00:00:00 UTC 1999
Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Herman JP,Spencer R
MA1-510 was used in western blot to demonstrate the regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo
Tue Sep 15 00:00:00 UTC 1998
A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling.
The Journal of biological chemistry
Caamaño CA,Morano MI,Dalman FC,Pratt WB,Akil H
MA1-510 was used in western blot to study the role of proline residue in the hsp90 binding region of the glucocorticoid receptor during the hsp90 heterocomplex stabilization and receptor signaling
Fri Aug 07 00:00:00 UTC 1998
The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.
The Journal of biological chemistry
Dittmar KD,Banach M,Galigniana MD,Pratt WB
MA1-510 was used in western blot to study the interaction between glucocorticoid receptor and hsp90
Fri Mar 27 00:00:00 UTC 1998
Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes.
Molecular endocrinology (Baltimore, Md.)
Barent RL,Nair SC,Carr DC,Ruan Y,Rimerman RA,Fulton J,Zhang Y,Smith DF
MA1-510 was used in immunoprecipitation to study the differences between the FKBP51 and FKBP52 during their association with Hsp90
Sun Mar 01 00:00:00 UTC 1998
The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signal.
Molecular endocrinology (Baltimore, Md.)
Tang Y,Getzenberg RH,Vietmeier BN,Stallcup MR,Eggert M,Renkawitz R,DeFranco DB
MA1-510 was used in immunocytochemistry to study the role of the glucocorticoid receptor's DNA-binding domain in the nuclear matrix targeting
Tue Sep 01 00:00:00 UTC 1998
In vivo analysis of the Hsp90 cochaperone Sti1 (p60).
Molecular and cellular biology
Chang HC,Nathan DF,Lindquist S
MA1-510 was used in western blot to detect the accumulation of GR
Wed Jan 01 00:00:00 UTC 1997
GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors.
Molecular and cellular biology
Hong H,Kohli K,Garabedian MJ,Stallcup MR
MA1-510 was used in western blot to investigate the important role of GRIP1 as a transcriptional coactivator interacting with the hormone binding domain of nuclear hormone receptors
Thu May 01 00:00:00 UTC 1997
Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.
The Journal of biological chemistry
Dittmar KD,Demady DR,Stancato LF,Krishna P,Pratt WB
MA1-510 was used in western blot to study the role of p23 during the formation of the GR.hsp90 heterocomplex
Fri Aug 22 00:00:00 UTC 1997
Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.
Proceedings of the National Academy of Sciences of the United States of America
Huss JM,Wang SI,Astrom A,McQuiddy P,Kasper CB
MA1-510 was used in EMSA assay to study the involvement of glucocorticoid receptor in dexamethasone responsivenes
Tue May 14 00:00:00 UTC 1996
Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.
The Journal of biological chemistry
Dittmar KD,Hutchison KA,Owens-Grillo JK,Pratt WB
MA1-510 was used in western blot to reconstitute a minimal GR-hsp90 heterocomplex assembly system
Fri May 31 00:00:00 UTC 1996
Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain.
The Journal of biological chemistry
Stancato LF,Silverstein AM,Gitler C,Groner B,Pratt WB
MA1-510 was used in western blot to characterize glucocorticoid receptor hormone binding domain using thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine
Fri Apr 12 00:00:00 UTC 1996
Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated gene expression.
Proceedings of the National Academy of Sciences of the United States of America
Renoir JM,Mercier-Bodard C,Hoffmann K,Le Bihan S,Ning YM,Sanchez ER,Handschumacher RE,Baulieu EE
MA1-510 was used in immunoprecipitation to characterize the effect of cyclosporin A in mouse fibroblast cells
Tue May 23 00:00:00 UTC 1995
Effect of stress on cochlear glucocorticoid protein. II. Restraint.
Hearing research
Curtis LM,Rarey KE
MA1-510 was used in ELISA to study the effect of restraint stress on the expression of the glucocorticoid receptor in the rat cochlear
Fri Dec 01 00:00:00 UTC 1995
Effect of stress on cochlear glucocorticoid protein: acoustic stress.
Hearing research
Rarey KE,Gerhardt KJ,Curtis LM,ten Cate WJ
MA1-510 was used in ELISA to study the effect of accoustic stress on the expression of glucocorticoid receptor protein in the cochlear
Wed Feb 01 00:00:00 UTC 1995
The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor.
The Journal of biological chemistry
Owens-Grillo JK,Hoffmann K,Hutchison KA,Yem AW,Deibel MR,Handschumacher RE,Pratt WB
MA1-510 was used in western blot to investigate the role of immunophilins in steroid receptor action
Fri Sep 01 00:00:00 UTC 1995
A functional glucocorticoid-responsive unit composed of two overlapping inactive receptor-binding sites: evidence for formation of a receptor tetramer.
Molecular and cellular biology
Garlatti M,Daheshia M,Slater E,Bouguet J,Hanoune J,Beato M,Barouki R
MA1-510 was used in EMSA assay to study the mechanism for glucocorticoid-responsive gene transcription
Thu Dec 01 00:00:00 UTC 1994
Absence of intramolecular disulfides in the structure and function of native rat glucocorticoid receptors.
The Journal of biological chemistry
Opoku J,Simons SS
MA1-510 was used in western blot to study the important roles of intramolecular disulfides in the structure and function of native rat GR
Fri Jan 07 00:00:00 UTC 1994
Androgen and glucocorticoid receptors interact with insulin degrading enzyme.
The Journal of biological chemistry
Kupfer SR,Wilson EM,French FS
MA1-510 was used in EMSA assay to investigate the interaction of androgen and glucocorticoid receptors with insulin degrading enzyme
Fri Aug 12 00:00:00 UTC 1994
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
The Journal of biological chemistry
Modarress KJ,Cavanaugh AH,Chakraborti PK,Simons SS
MA1-510 was used in western blot to study the mechanism for the effect of glucocorticoid receptor on metal oxyanion stabilization
Fri Oct 14 00:00:00 UTC 1994
Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae.
The Journal of biological chemistry
Chang HC,Lindquist S
MA1-510 was used in western blot to study the conservation of Hsp90 in budding yeast
Fri Oct 07 00:00:00 UTC 1994
Inhibition of mouse GATA-1 function by the glucocorticoid receptor: possible mechanism of steroid inhibition of erythroleukemia cell differentiation.
Molecular endocrinology (Baltimore, Md.)
Chang TJ,Scher BM,Waxman S,Scher W
MA1-510 was used in immunoprecipitation to investigate the inhibitory effect of glucocorticoid receptor on GATA-1 function
Thu Apr 01 00:00:00 UTC 1993
Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors.
Science (New York, N.Y.)
Yoshinaga SK,Peterson CL,Herskowitz I,Yamamoto KR
MA1-510 was used in immunoprecipitation to investigate the important roles of SWI isoforms in enhanced transcription mediated by steroid receptors
Fri Dec 04 00:00:00 UTC 1992
Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system.
The Journal of biological chemistry
Hutchison KA,Brott BK,De Leon JH,Perdew GH,Jove R,Pratt WB
MA1-510 was used in immunoprecipitation to reconstitute a complex based on pp60v-src, hsp90 and p50 proteins
Sat Feb 15 00:00:00 UTC 1992
Comparison of the 90-kilodalton heat shock protein interaction with in vitro translated glucocorticoid and estrogen receptors.
Molecular endocrinology (Baltimore, Md.)
Schlatter LK,Howard KJ,Parker MG,Distelhorst CW
MA1-510 was used in immunoprecipitation to study the interaction between 90-kilodalton heat shock protein and glucocorticoid and estrogen receptors
Wed Jan 01 00:00:00 UTC 1992
Kinetic pulse-chase labeling study of the glucocorticoid receptor in mouse lymphoma cells. Effect of glucocorticoid and antiglucocorticoid hormones on intracellular receptor half-life.
The Journal of biological chemistry
Distelhorst CW,Howard KJ
MA1-510 was used in immunoprecipitation to investigate the dynamics of the glucocorticoid receptor in S49 mouse lymphoma cells
Sat Aug 05 00:00:00 UTC 1989
Phosphorylation of glucocorticoid receptor-associated and free forms of the approximately 90-kDa heat shock protein before and after receptor activation.
The Journal of biological chemistry
Ortí E,Mendel DB,Munck A
MA1-510 was used in immunoprecipitation to purify three forms of Hsp 90 from WEHI-7 mouse thymoma cells and evaluate the phosphorylation level of each form
Thu Jan 05 00:00:00 UTC 1989
Isolation of ribonucleic acid from the unactivated rat liver glucocorticoid receptor.
Molecular endocrinology (Baltimore, Md.)
Unger AL,Uppaluri R,Ahern S,Colby JL,Tymoczko JL
MA1-510 was used in immunoprecipitation to investigate the association of RNA with glucocorticoid receptor
Sat Oct 01 00:00:00 UTC 1988
Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.
The Journal of biological chemistry
Howard KJ,Distelhorst CW
MA1-510 was used in immunoprecipitation to investigate the interaction between glucocorticoid receptor and hsp90
Sat Mar 05 00:00:00 UTC 1988
Analysis of the disruptive action of an epididymal protease and the stabilizing influence of molybdate on nondenatured and denatured glucocorticoid receptor.
Endocrinology
Hendry WJ,Danzo BJ,Harrison RW
MA1-510 was used in western blot to investigate epididymal protease's and molybdate's impacts on the structure of steroid receptor
Sun Feb 01 00:00:00 UTC 1987
