Product References
TNF-α Regulates the Glucocorticoid Receptor Alpha Expression in Human Nasal Epithelial Cells Via p65-NF-κb and p38-MAPK Signaling Pathways.
Iranian journal of biotechnology
Jiang Y,Liu B,Bao X,Zhou P,Li J
PA3-514 was used in Western Blotting to explore changes in inflammatory cytokines and glucocorticoid receptor alpha isoform (GRα) expression in HNECs.
Sun Jan 01 00:00:00 UTC 2023
Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension in mice.
Scientific reports
Patel GC,Liu Y,Millar JC,Clark AF
PA3-514 was used in Immunohistochemistry to study the in vivo physiological role of GRΒ in regulating GC-OHT and GC-mediated gene expression in the trabecular meshwork.
Tue Jan 16 00:00:00 UTC 2018
LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro.
Journal of inflammation (London, England)
Molina ML,Guerrero J,Cidlowski JA,Gatica H,Goecke A
PA3-514 was used in Western Blotting to show that LPS in vitro modulates the expression of glucocorticoid receptor (GR)α and GRΒ isoforms in a cell specific manner.
Wed Sep 30 00:00:00 UTC 2020
Annexin A1 in blood mononuclear cells from patients with coronary artery disease: Its association with inflammatory status and glucocorticoid sensitivity.
PloS one
Bergström I,Lundberg AK,Jönsson S,Särndahl E,Ernerudh J,Jonasson L
PA3514 was used in flow cytometry to examine AnxA1 in peripheral blood mononuclear cells from patients with coronary artery disease
Tue Aug 22 00:00:00 UTC 2017
Overexpression of GRß in colonic mucosal cell line partly reflects altered gene expression in colonic mucosa of patients with inflammatory bowel disease.
The Journal of steroid biochemistry and molecular biology
Nagy Z,Acs B,Butz H,Feldman K,Marta A,Szabo PM,Baghy K,Pazmany T,Racz K,Liko I,Patocs A
PA3-514 was used in immunocytochemistry to study patients with inflammatory bowel disease and altered gene expression in colonic mucosa by overexpression of Grbeta in colonic mucosal cell lines
Fri Jan 01 00:00:00 UTC 2016
Effects of maternal dexamethasone treatment early in pregnancy on glucocorticoid receptors in the ovine placenta.
Reproductive sciences (Thousand Oaks, Calif.)
Shang H,Meng W,Sloboda DM,Li S,Ehrlich L,Plagemann A,Dudenhausen JW,Henrich W,Newnham JP,Challis JR,Braun T
PA3-514 was used in immunohistochemistry and western blot to measure the expression of glucocorticoid receptors in pregnant ewes
Fri May 01 00:00:00 UTC 2015
Effects of maternal dexamethasone treatment early in pregnancy on glucocorticoid receptors in the ovine placenta.
Reproductive sciences (Thousand Oaks, Calif.)
Shang H,Meng W,Sloboda DM,Li S,Ehrlich L,Plagemann A,Dudenhausen JW,Henrich W,Newnham JP,Challis JR,Braun T
PA3-514 was used in immunohistochemistry and western blot to measure the expression of glucocorticoid receptors in pregnant ewes
Fri May 01 00:00:00 UTC 2015
Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: a prospective cohort study and in vitro experimental assay.
Critical care (London, England)
Guerrero J,Gatica HA,Rodríguez M,Estay R,Goecke IA
PA3-514 was used in western blot to study the effects of sepsis on sensitivity to glucocorticoids and glucocorticoid receptor isoform expression
Wed Jun 12 00:00:00 UTC 2013
Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: a prospective cohort study and in vitro experimental assay.
Critical care (London, England)
Guerrero J,Gatica HA,Rodríguez M,Estay R,Goecke IA
PA3-514 was used in western blot to study the effects of sepsis on sensitivity to glucocorticoids and glucocorticoid receptor isoform expression
Wed Jun 12 00:00:00 UTC 2013
Deficient glucocorticoid induction of anti-inflammatory genes in nasal polyp fibroblasts of asthmatic patients with and without aspirin intolerance.
The Journal of allergy and clinical immunology
Fernández-Bertolín L,Mullol J,Fuentes-Prado M,Alobid I,Roca-Ferrer J,Picado C,Pujols L
PA3-514 was used in Western Blotting to elucidate whether nasal polyp fibroblasts from patients with/without aspirin-intolerant asthma have alterations in the glucocorticoids signalling pathway explaining the insensitivity of these patients to glucocorticoids.
Fri Nov 01 00:00:00 UTC 2013
Glucocorticoid receptor and molecular chaperones in the pathogenesis of adrenal incidentalomas: potential role of reduced sensitivity to glucocorticoids.
Molecular medicine (Cambridge, Mass.)
Damjanovic SS,Antic JA,Ilic BB,Cokic BB,Ivovic M,Ognjanovic SI,Isailovic TV,Popovic BM,Bozic IB,Tatic S,Matic G,Todorovic VN,Paunovic I
PA3-514 was used in immunohistochemistry to study the pathogenesis of adrenal incidentalomas and the role of molecular chaperones, glucorticoid receptors and reduced glucocorticoid sensitivity
Tue Jan 22 00:00:00 UTC 2013
Effect of ionizing radiation on human skeletal muscle precursor cells.
Radiology and oncology
Jurdana M,Cemazar M,Pegan K,Mars T
PA3-514 was used in western blot to study the response of human skeletal muscle myoblasts to long-term ionizing radiation
Mon Dec 02 00:00:00 UTC 2013
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.
Thorax
Butler CA,McQuaid S,Taggart CC,Weldon S,Carter R,Skibinski G,Warke TJ,Choy DF,McGarvey LP,Bradding P,Arron JR,Heaney LG
PA3-514 was used in immunohistochemistry to investigate the expression of GR-beta and histone deacetylase 1 and 2 in severe asthma
Tue May 01 00:00:00 UTC 2012
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients.
Blood
Varricchio L,Masselli E,Alfani E,Battistini A,Migliaccio G,Vannucchi AM,Zhang W,Rondelli D,Godbold J,Ghinassi B,Whitsett C,Hoffman R,Migliaccio AR
PA3-514 was used in western blot to investigate the influence of the dominant negative GR beta isoform on erythropoiesis
Thu Jul 14 00:00:00 UTC 2011
Effects of methotrexate on the expression of the translational isoforms of glucocorticoid receptors α and β: correlation with methotrexate efficacy in rheumatoid arthritis patients.
Rheumatology (Oxford, England)
Gatica H,Aliste M,Guerrero J,Goecke IA
PA3-514 was used in western blot to investigate the influences of methotrexate on GR alpha/beta expression
Thu Sep 01 00:00:00 UTC 2011
Expression of glucocorticoid receptors in the regenerating human skeletal muscle.
Physiological research
Filipović D,Pirkmajer S,Mis K,Mars T,Grubic Z
PA3-514 was used in western blot to investigate glucocorticoid receptors in cultured human myoblasts and myotubes
Tue Feb 07 00:00:00 UTC 2012
Enhanced neutrophil expression of annexin-1 in coronary artery disease.
Metabolism: clinical and experimental
Särndahl E,Bergström I,Nijm J,Forslund T,Perretti M,Jonasson L
PA3-514 was used in flow cytometry to investigate the expression of annexin-1 in neutrophils in coronary artery disease patients
Mon Mar 01 00:00:00 UTC 2010
HIF-1alpha response to hypoxia is functionally separated from the glucocorticoid stress response in the in vitro regenerating human skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology
Pirkmajer S,Filipovic D,Mars T,Mis K,Grubic Z
PA3-514 was used in western blot to differentiate between HIF-1alpha response and glucocorticoid stress response in human skeletal muscle
Wed Dec 01 00:00:00 UTC 2010
Expression and distribution of glucocorticoid receptor isoforms in eosinophilic chronic rhinosinusitis.
Auris, nasus, larynx
Takeda K,Takeno S,Hirakawa K,Ishino T
PA3-514 was used in immunohistochemistry to investigate glucocorticoid receptor expression and distribution in eosinophilic chronic rhinosinusitis patients
Wed Dec 01 00:00:00 UTC 2010
Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells.
BMC medical genomics
Nehmé A,Lobenhofer EK,Stamer WD,Edelman JL
PA3-514 was used in Western Blotting to characterise the regulation of subsets of common and unique genes by varying glucocorticoids in the human trabecular meshwork cells.
Thu Sep 10 00:00:00 UTC 2009
Changes of glucocorticoid receptor expression in the nasal polyps of patients with chronic sinusitis following treatment with glucocorticoid.
In vivo (Athens, Greece)
Watanabe S,Suzaki H
PA3-514 was used in immunohistochemistry to investigate the level of glucocorticoid receptor protein in chronic sinusitis patients treated with glucocorticoids
Tue May 06 00:00:00 UTC 2008
Nitric oxide up-regulates the glucocorticoid receptor and blunts the inflammatory reaction in porcine endotoxin sepsis.
Critical care medicine
Da J,Chen L,Hedenstierna G
PA3-514 was used in immunohistochemistry to investigate the influence and mechanism of nitric oxide on endotoxin sepsis treatment
Mon Jan 01 00:00:00 UTC 2007
The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis.
Rheumatology (Oxford, England)
Kozaci DL,Chernajovsky Y,Chikanza IC
PA3-514 was used in flow cytometry to investigate the expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis
Sun Apr 01 00:00:00 UTC 2007
Human glucocorticoid receptor beta binds RU-486 and is transcriptionally active.
Molecular and cellular biology
Lewis-Tuffin LJ,Jewell CM,Bienstock RJ,Collins JB,Cidlowski JA
PA3-514 was used in western blot to investigate the functional properties of human glucocorticoid receptor beta
Thu Mar 01 00:00:00 UTC 2007
Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta.
Experimental eye research
Zhang X,Ognibene CM,Clark AF,Yorio T
PA3-514 was used in immunocytochemistry to study the effects of dexamethasone and glucocorticoid receptor beta on trabecular meshwork cell phagocytosis
Thu Feb 01 00:00:00 UTC 2007
Distribution of glucocorticoid receptor alpha and beta subtypes in the idiopathic inflammatory myopathies.
Neuromuscular disorders : NMD
De Bleecker JL,De Paepe B,Vervaet VL,Arys B,Creus KK,Werbrouck BF,Martin JJ
PA3-514 was used in immunohistochemistry and western blot to study the distribution of glucocorticoid receptor alpha and beta subtypes in idiopathic inflammatory myopathies
Thu Feb 01 00:00:00 UTC 2007
Expression of glucocorticoid receptors in non-neoplastic lymphoid follicles and B cell type malignant lymphomas.
Journal of clinical pathology
Okazaki SI,Yamakawa M,Maeda K,Ohta N,Aoyagi M
PA3-514 was used in immunohistochemistry to study the expression pattern of glucocorticoid receptors in normal and cancer lymphoid tissues.
Sat Apr 01 00:00:00 UTC 2006
The mitochondrion as a primary site of action of steroid and thyroid hormones: presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells.
Molecular and cellular endocrinology
Psarra AM,Solakidi S,Sekeris CE
PA3-514 was used in immunocytochemistry to study the presence and activity of steroid and thyroid hormone receptors in mitochondria
Sun Feb 26 00:00:00 UTC 2006
CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform.
Molecular pharmacology
Tliba O,Cidlowski JA,Amrani Y
PA3-514 was used in western blot to investigate the effect of glucocorticoid (GC) on CD38 expression in ASM cells treated with tumor necrosis factor-alpha and interferons
Wed Feb 01 00:00:00 UTC 2006
Expression and regulation of glucocorticoid receptor in human placental villous fibroblasts.
Endocrinology
Lee MJ,Wang Z,Yee H,Ma Y,Swenson N,Yang L,Kadner SS,Baergen RN,Logan SK,Garabedian MJ,Guller S
PA3-514 was used in western blot to characterize glucocorticoid receptor in human placental villous fibroblasts.
Tue Nov 01 00:00:00 UTC 2005
The human glucocorticoid receptor (hGR) beta isoform suppresses the transcriptional activity of hGRalpha by interfering with formation of active coactivator complexes.
Molecular endocrinology (Baltimore, Md.)
Charmandari E,Chrousos GP,Ichijo T,Bhattacharyya N,Vottero A,Souvatzoglou E,Kino T
PA3-514 was used in western blot to demonstrate the effect of human glucocorticoid receptor beta isoform on glucocorticoid receptor expression.
Sat Jan 01 00:00:00 UTC 2005
Glucocorticoid receptor alpha, beta and gamma expression vs in vitro glucocorticod resistance in childhood leukemia.
Leukemia
Haarman EG,Kaspers GJ,Pieters R,Rottier MM,Veerman AJ
PA3-514 was used in western blot to investigate the relationship between the expression of 3 isoforms of GR and in vitro GC resistance in childhood leukemia
Mon Mar 01 00:00:00 UTC 2004
Steroid-responsive sequences in the human glucocorticoid receptor gene 1A promoter.
Molecular endocrinology (Baltimore, Md.)
Geng CD,Vedeckis WV
PA3-514 was used in EMSA to investigate which promoter of the human glucocorticoid receptor protein gene contains the steroid-responsive sequences.
Thu Apr 01 00:00:00 UTC 2004
Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils.
The Journal of biological chemistry
Xu Q,Leung DY,Kisich KO
PA3-514 was used in western blot to investigate the role of serine-arginine-rich protein p30 during alternative splicing
Fri Jul 18 00:00:00 UTC 2003
Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids.
Molecular endocrinology (Baltimore, Md.)
Breslin MB,Geng CD,Vedeckis WV
PA3-514 was used in EMSA to study the activation of human glucocorticoid receptor gene promoter by glucocorticoids.
Wed Aug 01 00:00:00 UTC 2001
Western blotting for detection of glucocorticoid receptors in the brain and pituitary gland from adrenal intact pigs.
Brain research
Weaver SA,Schaefer AL,Dixon WT
PA3-514 was used in western blot to investigate the expression of glucocorticoid receptor in procine brain and pituitary gland
Fri Jun 30 00:00:00 UTC 2000
