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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predominantly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycine transporter 1; GlyT-1; Sodium- and chloride-dependent glycine transporter 1; Solute carrier family 6 member 9
Gene Aliases: Glyt-1; Glyt1; Slc6a9
UniProt ID: (Mouse) P28571
Entrez Gene ID: (Mouse) 14664
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