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The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
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Protein Aliases: Glycogen [starch] synthase, liver; glycogen liver; Glycogen synthase 2; glycogen synthase 2 (liver); glycogen synthase, liver
Gene Aliases: BC021322; GLYSN; GYS2; LGS
UniProt ID: (Human) P54840, (Mouse) Q8VCB3
Entrez Gene ID: (Pig) 100157080, (Human) 2998, (Mouse) 232493, (Rat) 25623
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