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Invitrogen
Glypican 1 Polyclonal Antibody
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Glypican 1 Antibody (PA5-77991) in IHC (P)
Glypican 1 Polyclonal Antibody detects Glypican 1 protein at cell membrane in human pancreas by immunohistochemical analysis. Sample: Paraffin-embedded human pancreas, normal (left) and cancer (right). Glypican 1 Polyclonal Antibody (Product # PA5-77991) diluted at 1:250. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-77991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Glypican 1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
2.04 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735860
Product Specific Information
Positive Control: A431, K562, MCF-7, AsPC-1, A431 (24 µg/mL Tunicamycin treatment for 16 hr), A431 (4 mM Benzyl glucosinolate treatment for 32 hr), A431(24 µg/mL Tunicamycin treatment for 16 hr and 4 mM Benzyl glucosinolate treatment for 32 hr)
Predicted Reactivity: Mouse (89%), Rat (90%), Rhesus Monkey (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glypican proteoglycan 1; Glypican-1
Gene Aliases: glypican; GPC1
UniProt ID: (Human) P35052
Entrez Gene ID: (Human) 2817
retinoid metabolic process
glycosaminoglycan biosynthetic process
glycosaminoglycan catabolic process
axon guidance
Schwann cell differentiation
heparan sulfate proteoglycan catabolic process
glycosaminoglycan metabolic process
myelin assembly
negative regulation of fibroblast growth factor receptor signaling pathway
positive regulation of skeletal muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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