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Invitrogen
Gram Negative Endotoxin Monoclonal Antibody (HEC11-445.2)
Product Details
MA1-10691
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
HEC11-445.2
Immunogen
E. coli serotypes: O:111, B4 J5.
Conjugate
Form
Liquid
Concentration
1.33 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1074813
Product Specific Information
MA1-10691 detects Endotoxin from E. aerogenes, S. marcescens, P. mirabilis, A. calcoaceticus, and Ps. aeruginosa samples.
MA1-10691 has been successfully used in ELISA applications.
The MA1-10691 immunogen is E. coli serotypes: O:111, B4 J5.
Target Information
Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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