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Invitrogen
Granulins Polyclonal Antibody
FIGURE: 1 / 16
Granulins Antibody (PA5-27275) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Granulins was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Granulins Polyclonal Antibody (Product # PA5-27275) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-27275
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Granulins. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2544751
Product Specific Information
Recommended positive controls: HepG2, mouse kidney, rat kidney.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PCDGF is a glycoprotein and growth factor involved in the regulation of mitosis, early embryonic development, cell division, cell migration, cell survival, and hypothalamic differentiation. PCDGF is also known as progranulin because it is the precursor for smaller proteins known as epithelins or granulins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acrogranin; acrogranulin; Epithelin precursor; Epithelin/granulin precursor; Glycoprotein of 88 Kda; GP88; Granulin precursor; granulin-epithelin; granulins; PC cell-derived growth factor; PCDGF; PEPI; PGRN; Proepithelin; Progranulin
Gene Aliases: CLN11; epithelin; GEP; GP88; GRN; PCDGF; PEPI; PGRN
UniProt ID: (Human) P28799, (Rat) P23785, (Mouse) P28798
Entrez Gene ID: (Human) 2896, (Rat) 29143, (Mouse) 14824
blastocyst hatching
embryo implantation
positive regulation of neuron projection development
response to estradiol
chondrocyte proliferation
synaptic vesicle endocytosis
positive regulation of epithelial cell proliferation
male mating behavior
positive regulation of dendritic spine development
neural precursor cell proliferation
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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