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Invitrogen
Growth Hormone Receptor Polyclonal Antibody
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Growth Hormone Receptor Antibody (PA5-47094) in Neu
Neutralization of Growth Hormone Receptor in Nb2‚11 rat lymphoma cell line. Samples were incubated in Growth Hormone Receptor polyclonal antibody (Product # PA5-47094). Recombinant Human Growth Hormone R/GHR Fc Chimera inhibits Recombinant Human Growth Hormone induced proliferation in the Nb2‚11 rat lymphoma cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human Growth Hormone (... View More
Product Details
PA5-47094
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Growth Hormone R/GHR Ala27-Tyr264
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609512
Product Specific Information
In direct ELISAs, less than 10% cross-reactivity with recombinant mouse GHR and recombinant rat GHR is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
may play a role in chondrocyte differentiation and positive regulation of longitudinal bond growth and.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GH receptor; growth hormone binding protein; Growth hormone receptor; MGC124963; MGC156665; serum binding protein; Somatotropin receptor
Gene Aliases: GHBP; GHIP; GHR
UniProt ID: (Human) P10912
Entrez Gene ID: (Human) 2690
activation of MAPK activity
allantoin metabolic process
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
endocytosis
JAK-STAT cascade
cytokine-mediated signaling pathway
taurine metabolic process
cellular response to hormone stimulus
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
activation of JAK2 kinase activity
multicellular organism metabolic process
creatinine metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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