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Invitrogen
Growth Hormone Receptor Polyclonal Antibody
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Growth Hormone Receptor Antibody (PA5-47095) in Neu
Neutralization of Growth Hormone Receptor in Nb2‚11 rat lymphoma cell line. Samples were incubated in Growth Hormone Receptor polyclonal antibody (Product # PA5-47095). Recombinant Rat Growth Hormone R/GHR Fc Chimera inhibits Recombinant Human Growth Hormone induced proliferation in the Nb2‚11 rat lymphoma cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human Growth Hormone (0.... View More
Product Details
PA5-47095
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Growth Hormone R/GHR Phe19-Arg265
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609367
Product Specific Information
In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse GHR and recombinant human GHR is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
may play a role in chondrocyte differentiation and positive regulation of longitudinal bond growth and.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GH receptor; Growth hormone receptor; growth hormone receptor precursor splice variant D56; growth hormone receptor variant d5-6; growth hormone receptor/binding protein; MGC124963; MGC156665; Somatotropin receptor
Gene Aliases: Ghr; GHR/BP
UniProt ID: (Rat) P16310
Entrez Gene ID: (Rat) 25235
activation of MAPK activity
allantoin metabolic process
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
JAK-STAT cascade
response to hormone
hormone-mediated signaling pathway
cytokine-mediated signaling pathway
taurine metabolic process
receptor internalization
response to food
response to estradiol
cellular response to insulin stimulus
cellular response to hormone stimulus
response to cytokine
regulation of multicellular organism growth
positive regulation of multicellular organism growth
activation of Janus kinase activity
activation of JAK2 kinase activity
response to morphine
response to peptide hormone
multicellular organism metabolic process
positive regulation of cell differentiation
positive regulation of JAK-STAT cascade
creatinine metabolic process
response to cycloheximide
insulin-like growth factor receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
response to glucocorticoid
cartilage development involved in endochondral bone morphogenesis
growth hormone receptor signaling pathway
response to interleukin-1
negative regulation of neuron death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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