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Peptide sequence: SSGAGGRGRT CSRTVRAELS FSVSQVERSL REGHYAQRLS RTAPVYLAAV
Sequence homology: Human: 100%
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H2A Barr body-deficient; H2A histone family, member B1; H2A.B; Histone H2A-Bbd type 1
Gene Aliases: H2A.Bbd; H2AB1; H2AFB1
UniProt ID: (Human) P0C5Y9
Entrez Gene ID: (Human) 474382
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