Proteintech

HA tag Polyclonal Antibody

HA tag Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

HA tag Antibody (51064-2-AP) in ICC/IF

Immunofluorescent analysis of Transfected HEK-293 cells using 51064-2-AP (HA tag antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

HA tag Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

51064-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:8,000

View 349 publications 349 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

View 32 publications 32 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 133 publications 133 publications

ChIP assay (ChIP)

View 4 publications 4 publications

Miscellaneous PubMed (MISC)

View 32 publications 32 publications

Not applicable (N/A)

View 96 publications 96 publications

Product Specifications

Species Reactivity

Tag

Published species

Human, Tag

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.81 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

HA Tag (hemagglutinin tag) is an epitope tag that provides a method to localize gene products in a variety of cell types, study the topology of proteins and protein complexes, identify associated proteins, and characterize newly identified, low abundance or poorly immunogenic proteins when protein specific antibodies are not available. HA (hemagglutinin) is a surface glycoprotein derived from influenza hemagglutinin, and is commonly expressed as a tag in conjunction with proteins to aid in identification and purification of the tagged protein for functional analysis. HA tag antibodies can be used to facilitate protein detection or co-immunopreciptation of tagged proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice.

eLife

Xu K,Su X,Fang K,Lv Y,Huang T,Li M,Wang Z,Yin Y,Muhammad T,Liu S,Chen X,Jiang J,Li J,Chan WY,Ma J,Lu G,Chen ZJ,Liu H

Tue Mar 21 00:00:00 UTC 2023

Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.

Cancer letters

Wang S,Huo X,Yang Y,Mo Y,Kollipara RK,Kittler R

Sun Jan 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

Oncogene

Li D,Wang Y,Dong C,Chen T,Dong A,Ren J,Li W,Shu G,Yang J,Shen W,Qin L,Hu L,Zhou J

Sun Jan 01 00:00:00 UTC 2023

PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.

Journal of medical virology

Lin YY,Yao R,Zhuang J,Wang B,Du L,Guo D,Pan JA,Peng X

Thu Jun 01 00:00:00 UTC 2023

PACT inhibits the replication of SARS-CoV-2 through the blockage of GSK-3β-N-nsp3 cascade.

Journal of medical virology

Lin YY,Yao R,Zhuang J,Wang B,Du L,Guo D,Pan JA,Peng X

Thu Jun 01 00:00:00 UTC 2023

OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes.

Theranostics

Wang M,Han X,Yu T,Wang M,Luo W,Zou C,Li X,Li G,Wu G,Wang Y,Liang G

Fri May 12 00:00:00 UTC 2023

The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.

Journal of virology

Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X

Thu Apr 27 00:00:00 UTC 2023

The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.

Journal of virology

Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X

Thu Apr 27 00:00:00 UTC 2023

The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.

Journal of virology

Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X

Thu Apr 27 00:00:00 UTC 2023

Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia.

Cell death discovery

Feng Y,Li L,Zhang Q,He Y,Huang Y,Zhang J,Zhang D,Huang Y,Lei X,Hu J,Luo G

Wed May 17 00:00:00 UTC 2023

Corticotropin-releasing factor potentiates glutamatergic input and excitability of presympathetic neurons in the hypothalamus in spontaneously hypertensive rats.

Neuropharmacology

Ma H,Cui Z,Guo X,Zhao Q,Zhang Y,Guan Y,Yang P,Zhu H,Wang S,Zhang X,Zhang Y,Pan HL,Ma H

Thu Jun 01 00:00:00 UTC 2023

Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis.

Molecular therapy : the journal of the American Society of Gene Therapy

Lian J,Zhu X,Du J,Huang B,Zhao F,Ma C,Guo R,Zhang Y,Ji L,Yahaya BH,Lin J

Wed May 03 00:00:00 UTC 2023

Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis.

Journal of innate immunity

Luo X,Ji R,Liu Q,Xiao X,Song W,An H,Li Y,Zhou J

Tue Dec 26 00:00:00 UTC 2023

T7 peptide-decorated exosome-based nanocarrier system for delivery of Galectin-9 siRNA to stimulate macrophage repolarization in glioblastoma.

Journal of neuro-oncology

Li C,Guan N,Liu F

Wed Mar 01 00:00:00 UTC 2023

Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.

Cell & bioscience

Sui L,Zhao Y,Wang W,Chi H,Tian T,Wu P,Zhang J,Zhao Y,Wei ZK,Hou Z,Zhou G,Wang G,Wang Z,Liu Q

Fri Jan 13 00:00:00 UTC 2023

A dual-regulation inducible switch system for microRNA detection and cell type-specific gene activation.

Theranostics

Shu WJ,Lee K,Ma Z,Tian X,Kim JS,Wang F

Wed May 24 00:00:00 UTC 2023

Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.

Hepatology (Baltimore, Md.)

Liu X,Tan S,Liu H,Jiang J,Wang X,Li L,Wu B

Sat Apr 01 00:00:00 UTC 2023

USP10 Regulates ZEB1 Ubiquitination and Protein Stability to Inhibit ZEB1-Mediated Colorectal Cancer Metastasis.

Molecular cancer research : MCR

Sun L,Yu J,Guinney J,Qin B,Sinicrope FA

Thu Jun 01 00:00:00 UTC 2023

USP10 Regulates ZEB1 Ubiquitination and Protein Stability to Inhibit ZEB1-Mediated Colorectal Cancer Metastasis.

Molecular cancer research : MCR

Sun L,Yu J,Guinney J,Qin B,Sinicrope FA

Thu Jun 01 00:00:00 UTC 2023

Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.

iScience

Zhang C,Liu Z,Wang X,Zhang B,Cui L,Hu Q,Hu B,Cao K,Shan W,Shi H,Wang R

Fri Jun 16 00:00:00 UTC 2023

Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.

iScience

Zhang C,Liu Z,Wang X,Zhang B,Cui L,Hu Q,Hu B,Cao K,Shan W,Shi H,Wang R

Fri Jun 16 00:00:00 UTC 2023

δ-Catenin Requirement in Keratinocyte Proliferation and DNA Repair Identifies a Therapeutic Target for Photoaging.

The Journal of investigative dermatology

Shen Y,Kim K,Zhu Z,Zhang S,Jiang M,Liu Z,Zheng Y,Li X,Jin L,Cong W

Sun Jan 01 00:00:00 UTC 2023

The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation.

Proceedings of the National Academy of Sciences of the United States of America

Ma Q,Jiang H,Ma L,Zhao G,Xu Q,Guo D,He N,Liu H,Meng Z,Liu J,Zhu L,Lin Q,Wu X,Li M,Luo S,Fang J,Lu Z

Tue Apr 11 00:00:00 UTC 2023

Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3.

Cell death and differentiation

Liu X,Fang Y,Lv X,Hu C,Chen G,Zhang L,Jin B,Huang L,Luo W,Liang G,Wang Y

Thu Jun 01 00:00:00 UTC 2023

Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3.

Cell death and differentiation

Liu X,Fang Y,Lv X,Hu C,Chen G,Zhang L,Jin B,Huang L,Luo W,Liang G,Wang Y

Thu Jun 01 00:00:00 UTC 2023

Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3.

Cell death and differentiation

Liu X,Fang Y,Lv X,Hu C,Chen G,Zhang L,Jin B,Huang L,Luo W,Liang G,Wang Y

Thu Jun 01 00:00:00 UTC 2023

B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.

Signal transduction and targeted therapy

Zhou C,Zhu X,Liu N,Dong X,Zhang X,Huang H,Tang Y,Liu S,Hu M,Wang M,Deng X,Li S,Zhang R,Huang Y,Lyu H,Xiao S,Luo S,Ali DW,Michalak M,Chen XZ,Wang Z,Tang J

Fri Feb 17 00:00:00 UTC 2023

Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.

Journal of cellular physiology

Guo L,Jiang ZM,Zhan YJ,Pan W,Wu QW,Song FX,Zhou X,Zhou XY,Liu LJ,Wang JT

Thu Jun 01 00:00:00 UTC 2023

An ankylosing spondylitis risk variant alters osteoclast differentiation.

Rheumatology (Oxford, England)

Wu F,Han X,Liu J,Zhang Z,Yan K,Wang B,Yang L,Zou H,Yang C,Huang W,Jin L,Wang J,Qian F,Niu Z

Tue May 02 00:00:00 UTC 2023

TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition.

Chinese medical journal

Song H,Xiao Q,Xu F,Wei Q,Wang F,Tan G

Wed Apr 05 00:00:00 UTC 2023

TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition.

Chinese medical journal

Song H,Xiao Q,Xu F,Wei Q,Wang F,Tan G

Wed Apr 05 00:00:00 UTC 2023

RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.

Molecular cell

Li Y,Huang J,Bao L,Zhu J,Duan W,Zheng H,Wang H,Jiang Y,Liu W,Zhang M,Yu Y,Yi C,Ji X

Thu Apr 20 00:00:00 UTC 2023

RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits.

Molecular cell

Li Y,Huang J,Bao L,Zhu J,Duan W,Zheng H,Wang H,Jiang Y,Liu W,Zhang M,Yu Y,Yi C,Ji X

Thu Apr 20 00:00:00 UTC 2023

Kremen2 drives the progression of non-small cell lung cancer by preventing SOCS3-mediated degradation of EGFR.

Journal of experimental & clinical cancer research : CR

Sun Y,Gao Y,Dong M,Li J,Li X,He N,Song H,Zhang M,Ji K,Wang J,Gu Y,Wang Y,Du L,Liu Y,Wang Q,Zhai H,Sun D,Liu Q,Xu C

Sat Jun 03 00:00:00 UTC 2023

The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.

Oncogene

Wu YY,Xiao YF,Tian LX,He B,Liu J,Li ZB,Yang H,Chen Y,Luo Q,Li BS,Yang SM

Wed Mar 01 00:00:00 UTC 2023

USP39 Regulates NF-κB-Mediated Inflammatory Responses through Deubiquitinating K48-Linked IκBα.

Journal of immunology (Baltimore, Md. : 1950)

Quan J,Zhao X,Xiao Y,Wu H,Di Q,Wu Z,Chen X,Tang H,Zhao J,Guan Y,Xu Y,Chen W

Wed Mar 01 00:00:00 UTC 2023

Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.

Journal of immunology (Baltimore, Md. : 1950)

Farris LC,Torres-Odio S,Adams LG,West AP,Hyde JA

Thu Jun 01 00:00:00 UTC 2023

Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1.

Antioxidants & redox signaling

Li S,Xiao H,Sun X,Chen Z,Lin Z,Li C,Zeng J,Xu Z,Cheng Y,Huang H

Tue Aug 01 00:00:00 UTC 2023

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.

Cancers

Caballero-Ruiz B,Gkotsi DS,Ollerton H,Morales-Alcala CC,Bordone R,Jenkins GML,Di Magno L,Canettieri G,Riobo-Del Galdo NA

Fri Jan 06 00:00:00 UTC 2023

PTEN Deficiency Facilitates Exosome Secretion and Metastasis in Cholangiocarcinoma by Impairing TFEB-mediated Lysosome Biogenesis.

Gastroenterology

Jiang TY,Shi YY,Cui XW,Pan YF,Lin YK,Feng XF,Ding ZW,Yang C,Tan YX,Dong LW,Wang HY

Wed Mar 01 00:00:00 UTC 2023

Up-regulated oxidized USP2a can increase Mdm2-p60-p53 to promote cell apoptosis.

Experimental cell research

Zhu H,Zhang H,Guo J,Zhang C,Zhang Q,Gao F

Thu Jun 01 00:00:00 UTC 2023

Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.

Cancer cell

Fang L,Hao Y,Yu H,Gu X,Peng Q,Zhuo H,Li Y,Liu Z,Wang J,Chen Y,Zhang J,Tian H,Gao Y,Gao R,Teng H,Shan Z,Zhu J,Li Z,Liu Y,Zhang Y,Yu F,Lin Z,Hao Y,Ge X,Yuan J,Hu HG,Ma Y,Qin HL,Wang P

Mon Jun 12 00:00:00 UTC 2023

The interaction between the histone acetyltransferase complex Hat1-Hat2 and transcription factor AmyR provides a molecular brake to regulate amylase gene expression.

Molecular microbiology

Hu Y,Liu Z,Xu S,Zhao Q,Liu G,Song X,Qu Y,Qin Y

Sat Apr 01 00:00:00 UTC 2023

AKT Blocks SIK1-Mediated Repression of STAT3 to Promote Breast Tumorigenesis.

Cancer research

Sun Z,Jiang Q,Gao B,Zhang X,Bu L,Wang L,Lin Y,Xie W,Li J,Guo J

Fri Apr 14 00:00:00 UTC 2023

RHDV 3C protein antagonizes type I interferon signaling by cleaving interferon promoter stimulated 1 protein.

Virus genes

Men Y,Wang Y,Wang H,Zhang M,Liu J,Chen Y,Han X,Chen R,Chen Q,Hu A

Sat Apr 01 00:00:00 UTC 2023

Stabilization of estrogen receptor α by USP37 contributes to the progression of breast cancer.

Cancer science

Cao J,Wang X,Wang S,Chen Z,Tang J

Mon May 01 00:00:00 UTC 2023

Stabilization of estrogen receptor α by USP37 contributes to the progression of breast cancer.

Cancer science

Cao J,Wang X,Wang S,Chen Z,Tang J

Mon May 01 00:00:00 UTC 2023

Gain-of-Function p53N236S Mutation Drives the Bypassing of HRas^V12-Induced Cellular Senescence via PGC-1α.

International journal of molecular sciences

Yang H,Zhang K,Guo Y,Guo X,Hou K,Hou J,Luo Y,Liu J,Jia S

Tue Feb 14 00:00:00 UTC 2023

The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK).

PLoS pathogens

Ponnuraj N,Akbar H,Arrington JV,Spatz SJ,Nagarajan B,Desai UR,Jarosinski KW

Wed Feb 01 00:00:00 UTC 2023

The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK).

PLoS pathogens

Ponnuraj N,Akbar H,Arrington JV,Spatz SJ,Nagarajan B,Desai UR,Jarosinski KW

Wed Feb 01 00:00:00 UTC 2023

PLAGL2 promotes Snail expression and gastric cancer progression via UCA1/miR-145-5p/YTHDF1 axis.

Carcinogenesis

Chen W,He Q,Liu J,Li N,Xiao K,Chen H

Sat Jun 24 00:00:00 UTC 2023

Impaired activity and membrane association of most calpain-5 mutants causal for neovascular inflammatory vitreoretinopathy.

Biochimica et biophysica acta. Molecular basis of disease

Geddes JW,Bondada V,Croall DE,Rodgers DW,Gal J

Tue Aug 01 00:00:00 UTC 2023

CCDC134 facilitates T cell activation through the regulation of early T cell receptor signaling.

Frontiers in immunology

Zhang T,Shi Q,Gu H,Yu B,Yin S,Ge Q,Mo X,Liu X,Huang J

Mon May 29 00:00:00 UTC 2023

USP39 attenuates the antitumor activity of cisplatin on colon cancer cells dependent on p53.

Cell biology and toxicology

Yuan J,Li X,Zhang Y,Zhang G,Cheng W,Wang W,Lei Y,Song G

Sun Oct 01 00:00:00 UTC 2023

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.

The Journal of clinical investigation

Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L

Fri Apr 01 00:00:00 UTC 2022

ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.

Cell death & disease

Geng S,Peng W,Wang X,Hu X,Liang H,Hou J,Wang F,Zhao G,Lü M,Cui H

Wed Jun 22 00:00:00 UTC 2022

Human cytomegalovirus UL24 and UL43 products participate in SAMHD1 subcellular localization.

Virusdisease

Sleman S,Najmuldeen H,Hao H,Jalal P,Saeed N,Othman D,Qian Z

Thu Dec 01 00:00:00 UTC 2022

EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.

The Journal of experimental medicine

Tao X,Zhang R,Du R,Yu T,Yang H,Li J,Wang Y,Liu Q,Zuo S,Wang X,Lazarus M,Zhou L,Wang B,Yu Y,Shen Y

Mon May 02 00:00:00 UTC 2022

EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.

The Journal of experimental medicine

Tao X,Zhang R,Du R,Yu T,Yang H,Li J,Wang Y,Liu Q,Zuo S,Wang X,Lazarus M,Zhou L,Wang B,Yu Y,Shen Y

Mon May 02 00:00:00 UTC 2022

A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing.

Journal of experimental & clinical cancer research : CR

Tang X,Deng Z,Ding P,Qiang W,Lu Y,Gao S,Hu Y,Yang Y,Du J,Gu C

Tue Mar 08 00:00:00 UTC 2022

Mechanosensitive Channel PIEZO1 Senses Shear Force to Induce KLF2/4 Expression via CaMKII/MEKK3/ERK5 Axis in Endothelial Cells.

Cells

Zheng Q,Zou Y,Teng P,Chen Z,Wu Y,Dai X,Li X,Hu Z,Wu S,Xu Y,Zou W,Song H,Ma L

Wed Jul 13 00:00:00 UTC 2022

DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.

Cellular oncology (Dordrecht, Netherlands)

Sun J,Wang X,Shen Q,Wang M,Chen S,Zhang X,Huang Y,Zhang Z,Li W,Yuan Y,Huang Z

Thu Dec 01 00:00:00 UTC 2022

DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2.

Cellular oncology (Dordrecht, Netherlands)

Sun J,Wang X,Shen Q,Wang M,Chen S,Zhang X,Huang Y,Zhang Z,Li W,Yuan Y,Huang Z

Thu Dec 01 00:00:00 UTC 2022

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.

Frontiers in endocrinology

Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M

Tue Jan 17 00:00:00 UTC 2023

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.

Frontiers in endocrinology

Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M

Tue Jan 17 00:00:00 UTC 2023

Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size.

Human molecular genetics

Gatford NJF,Deans PJM,Duarte RRR,Chennell G,Sellers KJ,Raval P,Srivastava DP

Thu Mar 03 00:00:00 UTC 2022

Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size.

Human molecular genetics

Gatford NJF,Deans PJM,Duarte RRR,Chennell G,Sellers KJ,Raval P,Srivastava DP

Thu Mar 03 00:00:00 UTC 2022

Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size.

Human molecular genetics

Gatford NJF,Deans PJM,Duarte RRR,Chennell G,Sellers KJ,Raval P,Srivastava DP

Thu Mar 03 00:00:00 UTC 2022

Essentiality of Sis1, a J-domain protein Hsp70 cochaperone, can be overcome by Tti1, a specialized PIKK chaperone.

Molecular biology of the cell

Schilke BA,Craig EA

Tue Mar 01 00:00:00 UTC 2022

Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.

Clinical and translational medicine

Zhang Y,Yu X,Sun R,Min J,Tang X,Lin Z,Xie S,Li X,Lu S,Tian Z,Gu C,Teng L,Yang Y

Tue Feb 01 00:00:00 UTC 2022

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.

Cell death discovery

Xu Z,Liu S,Feng C,Xu F,Kong D,Mi J,Yang C,Zhang G,Wei P,Orgil BO,Bergquist J,Tian G

Thu Dec 01 00:00:00 UTC 2022

ILF3 represses repeat-derived microRNAs targeting RIG-I mediated type I interferon response.

Journal of molecular biology

Chen G,Yang Y,Wu QJ,Cao L,Ruan W,Shao C,Jiang L,Tang P,Ma S,Jiang A,Wang Z,Wu K,Zhang QC,Fu XD,Zhou Y

Fri Apr 15 00:00:00 UTC 2022

Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway.

BMC women's health

Lin L,Gao Y,Hu X,Ouyang J,Liu C

Thu Nov 24 00:00:00 UTC 2022

A Deacetylase CqSIRT1 Promotes WSSV Infection by Binding to Viral Envelope Proteins in Cherax quadricarinatus.

Viruses

Zheng S,Meng F,Li D,Liu L,Ge D,Wang Q,Liu H

Sat Aug 06 00:00:00 UTC 2022

Seneca Valley Virus Induces DHX30 Cleavage to Antagonize Its Antiviral Effects.

Journal of virology

Wen W,Zheng Z,Wang H,Zhao Q,Yin M,Chen H,Li X,Qian P

Wed Sep 14 00:00:00 UTC 2022

Seneca Valley Virus Induces DHX30 Cleavage to Antagonize Its Antiviral Effects.

Journal of virology

Wen W,Zheng Z,Wang H,Zhao Q,Yin M,Chen H,Li X,Qian P

Wed Sep 14 00:00:00 UTC 2022

Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.

Theranostics

Chen T,Yuan Z,Lei Z,Duan J,Xue J,Lu T,Yan G,Zhang L,Liu Y,Li Q,Zhang Y

Thu Dec 08 00:00:00 UTC 2022

I226R Protein of African Swine Fever Virus Is a Suppressor of Innate Antiviral Responses.

Viruses

Hong J,Chi X,Yuan X,Wen F,Rai KR,Wu L,Song Z,Wang S,Guo G,Chen JL

Fri Mar 11 00:00:00 UTC 2022

Bacteria-mediated tumor immunotherapy via photothermally-programmed PD1 expression.

Nanoscale advances

Xu W,Ren D,Yu Z,Hou J,Huang F,Gan T,Ji P,Zhang C,Ma L,Hu Y

Tue Mar 15 00:00:00 UTC 2022

HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.

Cell death discovery

Zhang G,Zhu Q,Yan X,Ci M,Zhao E,Hou J,Wan S,Lü M,Cui H

Sat Apr 09 00:00:00 UTC 2022

HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.

Cell death discovery

Zhang G,Zhu Q,Yan X,Ci M,Zhao E,Hou J,Wan S,Lü M,Cui H

Sat Apr 09 00:00:00 UTC 2022

Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein.

Frontiers in microbiology

Ling YH,Wang H,Han MQ,Wang D,Hu YX,Zhou K,Li Y

Wed Sep 07 00:00:00 UTC 2022

C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.

Proceedings of the National Academy of Sciences of the United States of America

Ru Y,Yan X,Zhang B,Song L,Feng Q,Ye C,Zhou Z,Yang Z,Li Y,Zhang Z,Li Q,Mi W,Dong C

Tue Jul 26 00:00:00 UTC 2022

C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.

Proceedings of the National Academy of Sciences of the United States of America

Ru Y,Yan X,Zhang B,Song L,Feng Q,Ye C,Zhou Z,Yang Z,Li Y,Zhang Z,Li Q,Mi W,Dong C

Tue Jul 26 00:00:00 UTC 2022

Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.

Journal of extracellular vesicles

Yu X,Bai Y,Han B,Ju M,Tang T,Shen L,Li M,Yang L,Zhang Z,Hu G,Chao J,Zhang Y,Yao H

Sat Jan 01 00:00:00 UTC 2022

The nuclear receptor ERR cooperates with the cardiogenic factor GATA4 to orchestrate cardiomyocyte maturation.

Nature communications

Sakamoto T,Batmanov K,Wan S,Guo Y,Lai L,Vega RB,Kelly DP

Wed Apr 13 00:00:00 UTC 2022

PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.

Cell death & disease

Yang Q,Lu Y,Shangguan J,Shu X

Wed Nov 23 00:00:00 UTC 2022

Choline-induced SLC5A7 impairs colorectal cancer growth by stabilizing p53 protein.

Cancer letters

Yin Y,Jiang Z,Fu J,Li Y,Fang C,Yin X,Chen Y,Chen N,Li J,Ji Y,Su X,Qiu M,Huang W,Zhang B,Deng H,Dai L

Fri Jan 28 00:00:00 UTC 2022

USP39 facilitates breast cancer cell proliferation through stabilization of FOXM1.

American journal of cancer research

Zhang Z,Liu W,Bao X,Sun T,Wang J,Li M,Liu C

Tue Sep 20 00:00:00 UTC 2022

Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3.

Frontiers in immunology

Ma X,Di Q,Li X,Zhao X,Zhang R,Xiao Y,Li X,Wu H,Tang H,Quan J,Wu Z,Xiao W,Chen W

Mon Jul 25 00:00:00 UTC 2022

The interaction of O-GlcNAc-modified NLRX1 and IKK-α modulates IL-1β expression in M1 macrophages.

In vitro cellular & developmental biology. Animal

Chen L,Li Y,Zeng S,Duan S,Huang Z,Liang Y

Sun May 01 00:00:00 UTC 2022

N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.

Cancer letters

Sun Y,Guan Z,Sheng Q,Duan W,Zhao H,Zhou J,Deng Q,Pei X

Thu Mar 31 00:00:00 UTC 2022

N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.

Cancer letters

Sun Y,Guan Z,Sheng Q,Duan W,Zhao H,Zhou J,Deng Q,Pei X

Thu Mar 31 00:00:00 UTC 2022

HBx inhibits DNA sensing signaling pathway via ubiquitination and autophagy of cGAS.

Virology journal

Chen H,Jiang L,Chen S,Hu Q,Huang Y,Wu Y,Chen W

Mon Mar 28 00:00:00 UTC 2022

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Fri Sep 27 00:00:00 UTC 2024

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Fri Sep 27 00:00:00 UTC 2024

The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.

International journal of biological sciences

Huang G,Xiang Z,Wu H,He Q,Dou R,Lin Z,Yang C,Huang S,Song J,Di Z,Wang S,Xiong B

Fri Apr 15 00:00:00 UTC 2022

S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.

Cell reports

Sun Y,Zhang H,Meng J,Guo F,Ren D,Wu H,Jin X

Tue Aug 16 00:00:00 UTC 2022

Interaction of HnRNP F with the guanine-rich segments in viral antigenomic RNA enhances porcine reproductive and respiratory syndrome virus-2 replication.

Virology journal

Zhang A,Sun Y,Jing H,Liu J,Duan E,Ke W,Tao R,Li Y,Wang J,Cao S,Zhao P,Wang H,Zhang Y

Sun May 15 00:00:00 UTC 2022

Interaction of HnRNP F with the guanine-rich segments in viral antigenomic RNA enhances porcine reproductive and respiratory syndrome virus-2 replication.

Virology journal

Zhang A,Sun Y,Jing H,Liu J,Duan E,Ke W,Tao R,Li Y,Wang J,Cao S,Zhao P,Wang H,Zhang Y

Sun May 15 00:00:00 UTC 2022

The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.

Science advances

Yang H,Ting X,Geng YH,Xie Y,Nierenberg JL,Huo YF,Zhou YT,Huang Y,Yu YQ,Yu XY,Li XF,Ziv E,Zhang H,Fang WG,Shen Y,Tian XX

Fri Jun 10 00:00:00 UTC 2022

Phosphorylation of the Autographa californica multiple nucleopolyhedrovirus polyhedron envelope protein plays an important role in the formation of the occlusion body envelope.

The Journal of general virology

Wang J,Yang J,Lei C,Sun X,Hu J

Wed Jun 01 00:00:00 UTC 2022

PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence.

PLoS pathogens

Wang G,Zhao Y,Zhou Y,Jiang L,Liang L,Kong F,Yan Y,Wang X,Wang Y,Wen X,Zeng X,Tian G,Deng G,Shi J,Liu L,Chen H,Li C

Fri Apr 01 00:00:00 UTC 2022

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation.

Oncogene

Wei L,Wang W,Yao J,Cui Z,Xu Z,Ding H,Wu X,Wang D,Luo J,Ke ZJ

Thu Sep 01 00:00:00 UTC 2022

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation.

Oncogene

Wei L,Wang W,Yao J,Cui Z,Xu Z,Ding H,Wu X,Wang D,Luo J,Ke ZJ

Thu Sep 01 00:00:00 UTC 2022

Brown adipose tissue involution associated with progressive restriction in progenitor competence.

Cell reports

Huang Z,Zhang Z,Moazzami Z,Heck R,Hu P,Nanda H,Ren K,Sun Z,Bartolomucci A,Gao Y,Chung D,Zhu W,Shen S,Ruan HB

Tue Apr 12 00:00:00 UTC 2022

Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.

Frontiers in molecular neuroscience

Liu X,Zhang L,Zhang H,Liang X,Zhang B,Tu J,Zhao Y

Sat Jul 16 00:00:00 UTC 2022

Paired box 8 facilitates the c-MYC related cell cycle progress in TP53-mutation uterine corpus endometrial carcinoma through interaction with DDX5.

Cell death discovery

Qiu P,Jie Y,Ma C,Chen H,Qin Y,Tu K,Wang L,Zhang Z

Tue Jun 07 00:00:00 UTC 2022

SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation.

Oncogene

Hu X,Liu R,Hou J,Peng W,Wan S,Xu M,Li Y,Zhang G,Zhai X,Liang P,Cui H

Thu Sep 01 00:00:00 UTC 2022

SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation.

Oncogene

Hu X,Liu R,Hou J,Peng W,Wan S,Xu M,Li Y,Zhang G,Zhai X,Liang P,Cui H

Thu Sep 01 00:00:00 UTC 2022

ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

Nature cancer

Zhang T,Sun L,Hao Y,Suo C,Shen S,Wei H,Ma W,Zhang P,Wang T,Gu X,Li ST,Chen Z,Yan R,Zhang Y,Cai Y,Zhou R,Jia W,Huang F,Gao P,Zhang H

Sat Jan 01 00:00:00 UTC 2022

HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.

Cell biology international

Liu S,Song L,Yao H,Zhang L

Tue Mar 01 00:00:00 UTC 2022

PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhang C,Tang Q,Xia H,Xu H,Bi F

Sat Jan 01 00:00:00 UTC 2022

Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.

ACS chemical biology

Lyu Z,Sycks MM,Espinoza MF,Nguyen KK,Montoya MR,Galapate CM,Mei L,Genereux JC

Fri Jul 15 00:00:00 UTC 2022

Human ABCE1 exhibits temperature-dependent heterologous co-functionality in S. cerevisiae.

FEBS open bio

Wada M,Ito K

Sat Oct 01 00:00:00 UTC 2022

CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.

Cell death and differentiation

Xie W,Guo D,Li J,Yue L,Kang Q,Chen G,Zhou T,Wang H,Zhuang K,Leng L,Li H,Chen Z,Gao W,Zhang J

Thu Dec 01 00:00:00 UTC 2022

TRIP13 Induces Nedaplatin Resistance in Esophageal Squamous Cell Carcinoma by Enhancing Repair of DNA Damage and Inhibiting Apoptosis.

BioMed research international

Zhang LT,Ke LX,Wu XY,Tian HT,Deng HZ,Xu LY,Li EM,Long L

Tue May 24 00:00:00 UTC 2022

Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.

Cells

Qin M,Xin Y,Bian Y,Yang X,Xi T,Xiong J

Thu Jan 13 00:00:00 UTC 2022

TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization.

Cell death and differentiation

Gao W,Li Y,Liu X,Wang S,Mei P,Chen Z,Liu K,Li S,Xu XW,Gan J,Wu J,Ji C,Ding C,Liu X,Lai Y,He HH,Lieberman J,Wu H,Chen X,Li J

Tue Feb 01 00:00:00 UTC 2022

ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.

Virology journal

Zhang K,Wang S,Chen T,Tu Z,Huang X,Zang G,Wu C,Fan X,Liu J,Tian Y,Cheng Y,Lu N,Zhang G

Thu Dec 22 00:00:00 UTC 2022

ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.

Virology journal

Zhang K,Wang S,Chen T,Tu Z,Huang X,Zang G,Wu C,Fan X,Liu J,Tian Y,Cheng Y,Lu N,Zhang G

Thu Dec 22 00:00:00 UTC 2022

Chaperone-mediated autophagy degrades Keap1 and promotes Nrf2-mediated antioxidative response.

Aging cell

Zhu L,He S,Huang L,Ren D,Nie T,Tao K,Xia L,Lu F,Mao Z,Yang Q

Wed Jun 01 00:00:00 UTC 2022

Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine.

Immunity

Xiong Z,Zhu X,Geng J,Xu Y,Wu R,Li C,Fan D,Qin X,Du Y,Tian Y,Fan Z

Tue Apr 12 00:00:00 UTC 2022

Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.

Experimental cell research

Liu Y,Li Q,Geng L,Zhou X,Zhou X,Dong Y,Zhang Y

Sat Oct 01 00:00:00 UTC 2022

Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.

Theranostics

Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T

Thu Mar 10 00:00:00 UTC 2022

High expression of 14-3-3ơ indicates poor prognosis and progression of lung adenocarcinoma.

Oncology letters

Feng J,Leng J,Zhao C,Guo J,Chen Y,Li H

Fri Jul 01 00:00:00 UTC 2022

TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.

International journal of molecular sciences

Gu H,Zhu S,Peng C,Wei Z,Shen Y,Yuan C,Yang H,Cui H,Yang L

Mon Sep 05 00:00:00 UTC 2022

Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Li B,Chen X,Qiu W,Zhao R,Duan J,Zhang S,Pan Z,Zhao S,Guo Q,Qi Y,Wang W,Deng L,Ni S,Sang Y,Xue H,Liu H,Li G

Wed Jun 01 00:00:00 UTC 2022

USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.

Autophagy

Zhao X,Di Q,Yu J,Quan J,Xiao Y,Zhu H,Li H,Ling J,Chen W

Fri Apr 01 00:00:00 UTC 2022

FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1.

International journal of oral science

Zhao X,Chen H,Qiu Y,Cui L

Tue May 10 00:00:00 UTC 2022

Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.

Science advances

Feng D,Zhou J,Liu H,Wu X,Li F,Zhao J,Zhang Y,Wang L,Chao M,Wang Q,Qin H,Ge S,Liu Q,Zhang J,Qu Y

Fri Sep 30 00:00:00 UTC 2022

Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.

Cell insight

Zhou C,Dong X,Wang M,Qian X,Hu M,Liang K,Liang Y,Zhang R,Huang Y,Lyu H,Xiao S,Tang Y,Ali DW,Michalak M,Chen XZ,Tang J

Mon Aug 01 00:00:00 UTC 2022

Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity.

Cell insight

Zhou C,Dong X,Wang M,Qian X,Hu M,Liang K,Liang Y,Zhang R,Huang Y,Lyu H,Xiao S,Tang Y,Ali DW,Michalak M,Chen XZ,Tang J

Mon Aug 01 00:00:00 UTC 2022

Swine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway.

iScience

Zeng S,Zhao Y,Peng O,Xia Y,Xu Q,Li H,Xue C,Cao Y,Zhang H

Fri Nov 18 00:00:00 UTC 2022

Molecular characterization of the evolutionary conserved signaling intermediate in Toll pathways (ECSIT) of soiny mullet (Liza haematocheila).

Fish & shellfish immunology

Qi Z,Pi X,Xu Y,Zhang Q,Wangkahart E,Meng F,Wang Z

Tue Nov 01 00:00:00 UTC 2022

Molecular characterization of the evolutionary conserved signaling intermediate in Toll pathways (ECSIT) of soiny mullet (Liza haematocheila).

Fish & shellfish immunology

Qi Z,Pi X,Xu Y,Zhang Q,Wangkahart E,Meng F,Wang Z

Tue Nov 01 00:00:00 UTC 2022

Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.

PLoS pathogens

Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y

Sun May 01 00:00:00 UTC 2022

Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.

PLoS pathogens

Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y

Sun May 01 00:00:00 UTC 2022

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.

Cell death & disease

Song W,Zeng Z,Zhang Y,Li H,Cheng H,Wang J,Wu F

Sat Oct 08 00:00:00 UTC 2022

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.

Cell death & disease

Song W,Zeng Z,Zhang Y,Li H,Cheng H,Wang J,Wu F

Sat Oct 08 00:00:00 UTC 2022

Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.

Proceedings of the National Academy of Sciences of the United States of America

Sun X,Jing L,Li F,Zhang M,Diao X,Zhuang J,Rastinejad F,Wu D

Wed Nov 16 00:00:00 UTC 2022

PARK7 is induced to protect against endotoxic acute kidney injury by suppressing NF-κB.

Clinical science (London, England : 1979)

Li H,Liu Z,Wang Y,Wang H,Cai J,Tang C,Dong Z

Thu Dec 22 00:00:00 UTC 2022

Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.

Molecular therapy. Nucleic acids

Liu Y,Wang J,Chen J,Wu S,Zeng X,Xiong Q,Guo Y,Sun J,Song F,Xu J,Yuan S,Li C,He Y,Wang M,Chen L,Shi YB,Guo M,Guo D,Sun G

Tue Sep 13 00:00:00 UTC 2022

Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.

Cancer biomarkers : section A of Disease markers

Li X,Yang C,Luo N,Yang Y,Guo Y,Chen P,Cun B

Thu Jun 02 00:00:00 UTC 2022

The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.

The Journal of cell biology

Karasu OR,Neuner A,Atorino ES,Pereira G,Schiebel E

Mon Dec 05 00:00:00 UTC 2022

AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.

Journal of experimental & clinical cancer research : CR

Gu C,Wang Y,Zhang L,Qiao L,Sun S,Shao M,Tang X,Ding P,Tang C,Cao Y,Zhou Y,Guo M,Wei R,Li N,Xiao Y,Duan J,Yang Y

Thu Jan 06 00:00:00 UTC 2022

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

EMBO reports

Lin Y,Lv X,Sun C,Sun Y,Yang M,Ma D,Jing W,Zhao Y,Cheng Y,Xuan H,Han L

Mon Nov 07 00:00:00 UTC 2022

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

EMBO reports

Lin Y,Lv X,Sun C,Sun Y,Yang M,Ma D,Jing W,Zhao Y,Cheng Y,Xuan H,Han L

Mon Nov 07 00:00:00 UTC 2022

TurboID Identification of Evolutionarily Divergent Components of the Nuclear Pore Complex in the Malaria Model Plasmodium berghei.

mBio

Ambekar SV,Beck JR,Mair GR

Wed Oct 26 00:00:00 UTC 2022

Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.

Cell death & disease

Wu L,Yu K,Chen K,Zhu X,Yang Z,Wang Q,Gao J,Wang Y,Cao T,Xu H,Pan X,Wang L,Xia J,Li Y,Wang ZP,Ma J

Sat Mar 12 00:00:00 UTC 2022

Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.

Cell death & disease

Wu L,Yu K,Chen K,Zhu X,Yang Z,Wang Q,Gao J,Wang Y,Cao T,Xu H,Pan X,Wang L,Xia J,Li Y,Wang ZP,Ma J

Sat Mar 12 00:00:00 UTC 2022

Direct cardio-protection of Dapagliflozin against obesity-related cardiomyopathy via NHE1/MAPK signaling.

Acta pharmacologica Sinica

Lin K,Yang N,Luo W,Qian JF,Zhu WW,Ye SJ,Yuan CX,Xu DY,Liang G,Huang WJ,Shan PR

Sat Oct 01 00:00:00 UTC 2022

Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1.

Cell death and differentiation

Hu Y,Zhang H,Xie N,Liu D,Jiang Y,Liu Z,Ye D,Liu S,Chen X,Li C,Wang Q,Huang X,Liu Y,Shi Y,Zhang X

Wed Jun 01 00:00:00 UTC 2022

Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis.

Cell reports

Zheng Z,Yan G,Li X,Fei Y,Sun L,Yu H,Niu Y,Gao W,Zhong Q,Yan X

Tue Dec 20 00:00:00 UTC 2022

Identification of host cell proteins that interact with the M protein of Pigeon paramyxovirus type 1.

Protein expression and purification

Tao X,Zheng B,Liu X,Zhou T,Li B

Mon Aug 01 00:00:00 UTC 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 UTC 2022

Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.

Redox biology

Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y

Fri Jul 01 00:00:00 UTC 2022

Genome-Wide Analysis of the Indispensable Role of Non-structural Proteins in the Replication of SARS-CoV-2.

Frontiers in microbiology

Jin Y,Ouyang M,Yu T,Zhuang J,Wang W,Liu X,Duan F,Guo D,Peng X,Pan JA

Sat Jul 16 00:00:00 UTC 2022

TRX2/Rab35 Interaction Impairs Exosome Secretion by Inducing Rab35 Degradation.

International journal of molecular sciences

Zhang T,Zhao L,Han L,Li Y,Hu L,Wang H,Zou F

Sun Jun 12 00:00:00 UTC 2022

Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease.

iScience

Kaneshiro N,Komai M,Imaoka R,Ikeda A,Kamikubo Y,Saito T,Saido TC,Tomita T,Hashimoto T,Iwatsubo T,Sakurai T,Uehara T,Takasugi N

Fri Mar 18 00:00:00 UTC 2022

A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.

Journal of experimental & clinical cancer research : CR

Liu W,Ren D,Xiong W,Jin X,Zhu L

Wed Jan 26 00:00:00 UTC 2022

Type-III interferon stimulated gene TRIM31 mutation in an HBV patient blocks its ability in promoting HBx degradation.

Virus research

Xu F,Song H,Xiao Q,Wei Q,Pang X,Gao Y,Tan G

Sat Jan 15 00:00:00 UTC 2022

Type-III interferon stimulated gene TRIM31 mutation in an HBV patient blocks its ability in promoting HBx degradation.

Virus research

Xu F,Song H,Xiao Q,Wei Q,Pang X,Gao Y,Tan G

Sat Jan 15 00:00:00 UTC 2022

Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment.

The Journal of biological chemistry

He L,Jiang W,Li J,Wang C

Thu Sep 01 00:00:00 UTC 2022

MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1.

Cell death & disease

Zhang X,Luo Y,Cen Y,Qiu X,Li J,Jie M,Yang S,Qin S

Fri Nov 04 00:00:00 UTC 2022

Nutrient status regulates MED19a phase separation for ORESARA1-dependent senescence.

The New phytologist

Cheng SLH,Wu HW,Xu H,Singh RM,Yao T,Jang IC,Chua NH

Thu Dec 01 00:00:00 UTC 2022

Significance of NatB-mediated N-terminal acetylation of auxin biosynthetic enzymes in maintaining auxin homeostasis in Arabidopsis thaliana.

Communications biology

Liu HQ,Pu ZX,Di DW,Zou YJ,Guo YM,Wang JL,Zhang L,Tian P,Fei QH,Li XF,Khaskheli AJ,Wu L,Guo GQ

Thu Dec 22 00:00:00 UTC 2022

MFSD4A inhibits the malignant progression of nasopharyngeal carcinoma by targeting EPHA2.

Cell death & disease

Yang H,Qin G,Luo Z,Kong X,Gan C,Zhang R,Jiang W

Mon Apr 11 00:00:00 UTC 2022

Foot-and-mouth disease virus VP1 promotes viral replication by regulating the expression of chemokines and GBP1.

Frontiers in veterinary science

Yang L,Chen H,Liu L,Song J,Feng T,Li Y,Shen C,Kong L,Xin X

Tue Aug 09 00:00:00 UTC 2022

Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.

Nature communications

Sen A,Kallabis S,Gaedke F,Jüngst C,Boix J,Nüchel J,Maliphol K,Hofmann J,Schauss AC,Krüger M,Wiesner RJ,Pla-Martín D

Mon Nov 07 00:00:00 UTC 2022

Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.

Nature communications

Sen A,Kallabis S,Gaedke F,Jüngst C,Boix J,Nüchel J,Maliphol K,Hofmann J,Schauss AC,Krüger M,Wiesner RJ,Pla-Martín D

Mon Nov 07 00:00:00 UTC 2022

The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice.

Plant physiology

Hou J,Zheng X,Ren R,Shi Q,Xiao H,Chen Z,Yue M,Wu Y,Hou H,Li L

Wed Jun 01 00:00:00 UTC 2022

RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions.

Molecular cancer research : MCR

Cho JH,Park S,Kim S,Kang SM,Woo TG,Yoon MH,Lee H,Jeong M,Park YH,Kim H,Han YT,Suh YG,Kim BH,Kwon Y,Yun H,Park BJ

Tue Mar 01 00:00:00 UTC 2022

Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.

Viral immunology

Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z

Sat Oct 01 00:00:00 UTC 2022

Human Cytomegalovirus UL24 and UL43 Cooperate to Modulate the Expression of Immunoregulatory UL16 Binding Protein 1.

Viral immunology

Sleman S,Hao H,Najmuldeen H,Jalal P,Saeed N,Othman D,Qian Z

Sat Oct 01 00:00:00 UTC 2022

African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Journal of virology

Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X

Wed Sep 14 00:00:00 UTC 2022

African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Journal of virology

Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X

Wed Sep 14 00:00:00 UTC 2022

African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation.

Journal of virology

Li L,Fu J,Li J,Guo S,Chen Q,Zhang Y,Liu Z,Tan C,Chen H,Wang X

Wed Sep 14 00:00:00 UTC 2022

HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection.

Viruses

Li X,Xie J,Li D,Li H,Niu Y,Wu B,Yang Y,Yan Z,Zhang X,Chen L,Feng R

Tue Aug 23 00:00:00 UTC 2022

HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection.

Viruses

Li X,Xie J,Li D,Li H,Niu Y,Wu B,Yang Y,Yan Z,Zhang X,Chen L,Feng R

Tue Aug 23 00:00:00 UTC 2022

E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity.

Cell death and differentiation

Yoon J,Grinchuk OV,Tirado-Magallanes R,Ngian ZK,Tay EXY,Chuah YH,Lee BWL,Feng J,Crasta KC,Ong CT,Benoukraf T,Ong DST

Fri Jul 01 00:00:00 UTC 2022

CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.

Cell & bioscience

Si M,Song Y,Wang X,Wang D,Liu X,Qu X,Song Z,Yu X

Sun Oct 09 00:00:00 UTC 2022

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.

Frontiers in immunology

Li Y,Chen L,Huang R,Li Y,Yang C,Gui B,Li Y,Liao L,Zhu Z,Wang Y

Wed Sep 28 00:00:00 UTC 2022

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.

Frontiers in immunology

Li Y,Chen L,Huang R,Li Y,Yang C,Gui B,Li Y,Liao L,Zhu Z,Wang Y

Wed Sep 28 00:00:00 UTC 2022

The global succinylation of SARS-CoV-2-infected host cells reveals drug targets.

Proceedings of the National Academy of Sciences of the United States of America

Liu Q,Wang H,Zhang H,Sui L,Li L,Xu W,Du S,Hao P,Jiang Y,Chen J,Qu X,Tian M,Zhao Y,Guo X,Wang X,Song W,Song G,Wei Z,Hou Z,Wang G,Sun M,Li X,Lu H,Zhuang X,Jin N,Zhao Y,Li C,Liao M

Tue Jul 26 00:00:00 UTC 2022

Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.

Clinical and translational medicine

Lei Y,Han P,Chen Y,Wang H,Wang S,Wang M,Liu J,Yan W,Tian D,Liu M

Sat Jan 01 00:00:00 UTC 2022

Long non-coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer.

Clinical and translational medicine

Dai T,Zhang X,Zhou X,Hu X,Huang X,Xing F,Tian H,Li Y

Sat Oct 01 00:00:00 UTC 2022

Long non-coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer.

Clinical and translational medicine

Dai T,Zhang X,Zhou X,Hu X,Huang X,Xing F,Tian H,Li Y

Sat Oct 01 00:00:00 UTC 2022

Phosphorylation of α-Catenin^S641 Suppresses the NF-κB Pathway in Fibroblasts to Activate Skin Wound Repair.

The Journal of investigative dermatology

Shen Y,Zhu Z,Cong W,Jiang M,Wang J,Chen X,Wang N,Yu Y,Dong Y,Liu Z,Sun J,Gong W,Zhang S,Kim K,Jin L

Wed Jun 01 00:00:00 UTC 2022

PGE₂ -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.

The EMBO journal

Tao X,Du R,Guo S,Feng X,Yu T,OuYang Q,Chen Q,Fan X,Wang X,Guo C,Li X,Xue F,Chen S,Tong M,Lazarus M,Zuo S,Yu Y,Shen Y

Tue Aug 16 00:00:00 UTC 2022

PGE₂ -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.

The EMBO journal

Tao X,Du R,Guo S,Feng X,Yu T,OuYang Q,Chen Q,Fan X,Wang X,Guo C,Li X,Xue F,Chen S,Tong M,Lazarus M,Zuo S,Yu Y,Shen Y

Tue Aug 16 00:00:00 UTC 2022

Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.

Molecular cell

Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q

Thu May 19 00:00:00 UTC 2022

TAK1 is essential for endothelial barrier maintenance and repair after lung vascular injury.

Molecular biology of the cell

Wang DM,Soni D,Regmi SC,Vogel SM,Tiruppathi C

Wed Jun 01 00:00:00 UTC 2022

Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.

Theranostics

Liu G,Wang Q,Deng L,Huang X,Yang G,Cheng Q,Guo T,Guo L,Niu C,Yang X,Dong J,Zhang J

Thu Apr 21 00:00:00 UTC 2022

ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.

Cancer cell international

Zhang Y,Sun M,Gao L,Liang X,Ma C,Lu J,Yue X

Sat Feb 12 00:00:00 UTC 2022

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR.

Communications biology

Fu X,Zhao J,Yu G,Zhang X,Sun J,Li L,Yin J,Niu Y,Ren S,Zhu Y,Xu B,Huang L

Tue Mar 01 00:00:00 UTC 2022

The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.

iScience

Zhang G,Han J,Wang L,Yang X,Yan Z,Qu M,Zhou H,Bilal H,Wang F,Ge H,Yang X

Fri Apr 15 00:00:00 UTC 2022

The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.

iScience

Zhang G,Han J,Wang L,Yang X,Yan Z,Qu M,Zhou H,Bilal H,Wang F,Ge H,Yang X

Fri Apr 15 00:00:00 UTC 2022

The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.

iScience

Zhang G,Han J,Wang L,Yang X,Yan Z,Qu M,Zhou H,Bilal H,Wang F,Ge H,Yang X

Fri Apr 15 00:00:00 UTC 2022

TGF-β1-Mediated PD-L1 Glycosylation Contributes to Immune Escape via c-Jun/STT3A Pathway in Nasopharyngeal Carcinoma.

Frontiers in oncology

Ma XM,Luo YF,Zeng FF,Su C,Liu X,Li XP,Lu J

Tue Mar 22 00:00:00 UTC 2022

ZC3H15 promotes gastric cancer progression by targeting the FBXW7/c-Myc pathway.

Cell death discovery

Hou J,Huang P,Lan C,Geng S,Xu M,Liu Y,Chang H,Wang Z,Gu H,Wang Y,Yang G,Cui H

Fri Jan 21 00:00:00 UTC 2022

TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.

Molecular cell

Wang L,Li J,Wang Q,Ge MX,Ji J,Liu D,Wang Z,Cao Y,Zhang Y,Zhang ZR

Thu Sep 15 00:00:00 UTC 2022

A protective role for Drosophila Filamin in nephrocytes via Yorkie mediated hypertrophy.

Life science alliance

Koehler S,Huber TB,Denholm B

Wed Aug 03 00:00:00 UTC 2022

A Single Amino Acid Residue R144 of SNX16 Affects Its Ability to Inhibit the Replication of Influenza A Virus.

Viruses

Shi W,Jiang L,Ye M,Wang B,Chang Y,Shan Z,Wang X,Hu Y,Chen H,Li C

Fri Apr 15 00:00:00 UTC 2022

The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.

Biochemical and biophysical research communications

Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H

Sat Feb 19 00:00:00 UTC 2022

The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.

Biochemical and biophysical research communications

Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H

Sat Feb 19 00:00:00 UTC 2022

Deoxyhypusine hydroxylase as a novel pharmacological target for ischemic stroke via inducing a unique post-translational hypusination modification.

Pharmacological research

Guo Q,Zhang YC,Wang W,Wang YQ,Liu Y,Yang Z,Zhao MM,Feng N,Wang YH,Zhang XW,Yang H,Liu TT,Shi LY,Shi XM,Liu D,Tu PF,Zeng KW

Tue Feb 01 00:00:00 UTC 2022

TIAM-1 differentially regulates dendritic and axonal microtubule organization in patterning neuronal development through its multiple domains.

PLoS genetics

Lin CH,Chen YC,Chan SP,Ou CY

Sat Oct 01 00:00:00 UTC 2022

TIAM-1 differentially regulates dendritic and axonal microtubule organization in patterning neuronal development through its multiple domains.

PLoS genetics

Lin CH,Chen YC,Chan SP,Ou CY

Sat Oct 01 00:00:00 UTC 2022

Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.

Molecular therapy. Nucleic acids

Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R

Tue Jun 14 00:00:00 UTC 2022

Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.

Molecular therapy. Nucleic acids

Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R

Tue Jun 14 00:00:00 UTC 2022

COL10A1-DDR2 axis promotes the progression of pancreatic cancer by regulating MEK/ERK signal transduction.

Frontiers in oncology

Wen Z,Sun J,Luo J,Fu Y,Qiu Y,Li Y,Xu Y,Wu H,Zhang Q

Thu Dec 22 00:00:00 UTC 2022

Establishment and Phenotypic Analysis of the Novel Gaucher Disease Mouse Model With the Partially Humanized Gba1 Gene and F213I Mutation.

Frontiers in genetics

Guo JN,Guan M,Jiang N,Li N,Li YJ,Zhang J,Ma D

Sat Jul 16 00:00:00 UTC 2022

Lactylation-driven METTL3-mediated RNA m⁶A modification promotes immunosuppression of tumor-infiltrating myeloid cells.

Molecular cell

Xiong J,He J,Zhu J,Pan J,Liao W,Ye H,Wang H,Song Y,Du Y,Cui B,Xue M,Zheng W,Kong X,Jiang K,Ding K,Lai L,Wang Q

Thu May 05 00:00:00 UTC 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 UTC 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 UTC 2022

Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication.

Virulence

Yu J,Zhang W,Huo W,Meng X,Zhong T,Su Y,Liu Y,Liu J,Wang Z,Song F,Zhang S,Li Z,Yu X,Yu X,Hua S

Thu Dec 01 00:00:00 UTC 2022

DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS.

Frontiers in microbiology

Xie J,Li X,Yang S,Yan Z,Chen L,Yang Y,Li D,Zhang X,Feng R

Tue Sep 13 00:00:00 UTC 2022

Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome.

Pathogens (Basel, Switzerland)

Okura T,Shirato K,Kakizaki M,Sugimoto S,Matsuyama S,Tanaka T,Kume Y,Chishiki M,Ono T,Moriishi K,Sonoyama M,Hosoya M,Hashimoto K,Maenaka K,Takeda M

Wed Aug 03 00:00:00 UTC 2022

Reconstitution and mechanistic dissection of the human microtubule branching machinery.

The Journal of cell biology

Zhang Y,Hong X,Hua S,Jiang K

Mon Jul 04 00:00:00 UTC 2022

Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality.

Cell death & disease

Li P,Chen T,Kuang P,Liu F,Li Z,Liu F,Wang Y,Zhang W,Cai X

Wed Jul 13 00:00:00 UTC 2022

USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ.

Cell death & disease

Tang J,Luo Y,Xiao L

Sat Apr 09 00:00:00 UTC 2022

MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma.

Cell death & disease

Zhu J,Wu Y,Yu Y,Li Y,Shen J,Zhang R

Sat Aug 20 00:00:00 UTC 2022

OsMADS14 and NF-YB1 cooperate in the direct activation of OsAGPL2 and Waxy during starch synthesis in rice endosperm.

The New phytologist

Feng T,Wang L,Li L,Liu Y,Chong K,Theißen G,Meng Z

Fri Apr 01 00:00:00 UTC 2022

Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhu M,Wang H,Ding Y,Yang Y,Xu Z,Shi L,Zhang N

Sun May 01 00:00:00 UTC 2022

Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.

Frontiers in cardiovascular medicine

Wang M,Alabi A,Gu HM,Gill G,Zhang Z,Jarad S,Xia XD,Shen Y,Wang GQ,Zhang DW

Tue Sep 13 00:00:00 UTC 2022

ZC3H15 promotes glioblastoma progression through regulating EGFR stability.

Cell death & disease

Hou J,Xu M,Gu H,Pei D,Liu Y,Huang P,Chang H,Cui H

Thu Jan 13 00:00:00 UTC 2022

Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.

The EMBO journal

Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L

Thu Dec 01 00:00:00 UTC 2022

Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.

Journal of translational medicine

Zhou Z,Shu Y,Bao H,Han S,Liu Z,Zhao N,Yuan W,Jian C,Shu X

Tue Jun 07 00:00:00 UTC 2022

Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome.

Nature genetics

Cousin MA,Creighton BA,Breau KA,Spillmann RC,Torti E,Dontu S,Tripathi S,Ajit D,Edwards RJ,Afriyie S,Bay JC,Harper KM,Beltran AA,Munoz LJ,Falcon Rodriguez L,Stankewich MC,Person RE,Si Y,Normand EA,Blevins A,May AS,Bier L,Aggarwal V,Mancini GMS,van Slegtenhorst MA,Cremer K,Becker J,Engels H,Aretz S,MacKenzie JJ,Brilstra E,van Gassen KLI,van Jaarsveld RH,Oegema R,Parsons GM,Mark P,Helbig I,McKeown SE,Stratton R,Cogne B,Isidor B,Cacheiro P,Smedley D,Firth HV,Bierhals T,Kloth K,Weiss D,Fairley C,Shieh JT,Kritzer A,Jayakar P,Kurtz-Nelson E,Bernier RA,Wang T,Eichler EE,van de Laar IMBH,McConkie-Rosell A,McDonald MT,Kemppainen J,Lanpher BC,Schultz-Rogers LE,Gunderson LB,Pichurin PN,Yoon G,Zech M,Jech R,Winkelmann J,Beltran AS,Zimmermann MT,Temple B,Moy SS,Klee EW,Tan QK,Lorenzo DN

Thu Jul 01 00:00:00 UTC 2021

UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.

Neuron

Zhang K,Wang A,Zhong K,Qi S,Wei C,Shu X,Tu WY,Xu W,Xia C,Xiao Y,Chen A,Bai L,Zhang J,Luo B,Wang W,Shen C

Wed Jun 16 00:00:00 UTC 2021

Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain.

Molecular neurobiology

Wang SM,Goguadze N,Kimura Y,Yasui Y,Pan B,Wang TY,Nakamura Y,Lin YT,Hogan QH,Wilson KL,Su TP,Wu HE

Tue Jun 01 00:00:00 UTC 2021

Ring finger protein 19A is overexpressed in non-small cell lung cancer and mediates p53 ubiquitin-degradation to promote cancer growth.

Journal of cellular and molecular medicine

Cheng Y,Hu Y,Wang H,Zhao Z,Jiang X,Zhang Y,Zhang J,Tong Y,Qiu X

Sun Aug 01 00:00:00 UTC 2021

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.

Journal of cellular and molecular medicine

Hu B,Zhou S,Hu X,Zhang H,Lan X,Li M,Wang Y,Hu Q

Thu Jul 01 00:00:00 UTC 2021

A Novel Loss-of-Function MKRN3 Variant in a Chinese Patient With Familial Precocious Puberty: A Case Report and Functional Study.

Frontiers in genetics

Yin X,Wang J,Han T,Tingting Z,Li Y,Dong Z,Wang W,Li C,Lu W

Wed Apr 03 00:00:00 UTC 2024

ITPKA induces cell senescence, inhibits ovarian cancer tumorigenesis and can be downregulated by miR-203.

Aging

Shaosheng W,Shaochuang W,Lichun F,Na X,Xiaohong Z

Tue Apr 20 00:00:00 UTC 2021

Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.

FEBS letters

Qin S,Ye L,Zheng Y,Gao J

Mon Feb 01 00:00:00 UTC 2021

Regulation of survivin protein stability by USP35 is evolutionarily conserved.

Biochemical and biophysical research communications

Wang W,Lin H,Zheng E,Hou Z,Liu Y,Huang W,Chen D,Feng J,Li J,Li L

Fri Oct 15 00:00:00 UTC 2021

Regulation of survivin protein stability by USP35 is evolutionarily conserved.

Biochemical and biophysical research communications

Wang W,Lin H,Zheng E,Hou Z,Liu Y,Huang W,Chen D,Feng J,Li J,Li L

Fri Oct 15 00:00:00 UTC 2021

USP1 Promotes GC Metastasis via Stabilizing ID2.

Disease markers

Li N,Wu L,Zuo X,Luo H,Sheng Y,Yan J

Wed Mar 09 00:00:00 UTC 2022

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response.

Signal transduction and targeted therapy

Zhao Y,Sui L,Wu P,Wang W,Wang Z,Yu Y,Hou Z,Tan G,Liu Q,Wang G

Wed Sep 01 00:00:00 UTC 2021

USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.

Cell death & disease

Wu X,Wang H,Zhu D,Chai Y,Wang J,Dai W,Xiao Y,Tang W,Li J,Hong L,Pei M,Zhang J,Lin Z,Wang J,Li A,Liu S

Mon Dec 20 00:00:00 UTC 2021

Natural molecule Munronoid I attenuates LPS-induced acute lung injury by promoting the K48-linked ubiquitination and degradation of TAK1.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Ma X,Li X,Di Q,Zhao X,Zhang R,Xiao Y,Sun P,Tang H,Quan J,Xiao W,Chen W

Tue Jun 01 00:00:00 UTC 2021

Genomic Characterization of Diverse Bat Coronavirus HKU10 in Hipposideros Bats.

Viruses

Wang N,Luo CM,Yang XL,Liu HZ,Zhang LB,Zhang W,Li B,Zhu Y,Peng C,Shi ZL,Hu B

Wed Sep 29 00:00:00 UTC 2021

TDP-43 and PINK1 mediate CHCHD10^S59L mutation-induced defects in Drosophila and in vitro.

Nature communications

Baek M,Choe YJ,Bannwarth S,Kim J,Maitra S,Dorn GW,Taylor JP,Paquis-Flucklinger V,Kim NC

Fri Mar 26 00:00:00 UTC 2021

Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.

Frontiers in cellular and infection microbiology

Lei Y,Cao X,Xu W,Yang B,Xu Y,Zhou W,Dong S,Wu Q,Rahman K,Tyagi R,Zhao S,Chen X,Cao G

Mon Jul 05 00:00:00 UTC 2021

SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation.

Pharmacological research

Zhang Y,Ni L,Lin B,Hu L,Lin Z,Yang J,Wang J,Ma H,Liu Y,Yang J,Lin J,Xu L,Wu L,Shi D

Thu Jul 01 00:00:00 UTC 2021

Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis.

Scientific reports

Caliva MJ,Yang WS,Young-Robbins S,Zhou M,Yoon H,Matter ML,Grimes ML,Conrads T,Ramos JW

Wed Oct 06 00:00:00 UTC 2021

Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis.

Scientific reports

Caliva MJ,Yang WS,Young-Robbins S,Zhou M,Yoon H,Matter ML,Grimes ML,Conrads T,Ramos JW

Wed Oct 06 00:00:00 UTC 2021

Proteolytic Shedding of Human Colony-Stimulating Factor 1 Receptor and its implication.

Journal of cellular and molecular medicine

Wei Y,Ma M,Lin S,Li X,Shu Y,Wang Z,Zhou Y,Hu B,Cheng B,Duan S,Huang X,Xu H,Zhang YW,Zheng H

Sat May 01 00:00:00 UTC 2021

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.

Nature cell biology

Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC

Mon Mar 01 00:00:00 UTC 2021

Japanese Encephalitis Virus NS2B-3 Protein Complex Promotes Cell Apoptosis and Viral Particle Release by Down-Regulating the Expression of AXL.

Virologica Sinica

Xie S,Liang Z,Yang X,Pan J,Yu D,Li T,Cao R

Wed Dec 01 00:00:00 UTC 2021

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells.

Cell death & disease

Ji Y,Liu Y,Sun C,Yu L,Wang Z,Du X,Yang W,Zhang C,Tao C,Wang J,Yang X,Di S,Huang Y

Tue Apr 06 00:00:00 UTC 2021

ZBTB38 suppresses prostate cancer cell proliferation and migration via directly promoting DKK1 expression.

Cell death & disease

Ding G,Lu W,Zhang Q,Li K,Zhou H,Wang F,Zhao C,Fan C,Wang J

Mon Oct 25 00:00:00 UTC 2021

Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway.

Gene

Zhang W,Wu Y,Chen H,Yu D,Zhao J,Chen J

Sat Jan 30 00:00:00 UTC 2021

NPRL2 reduces the niraparib sensitivity of castration-resistant prostate cancer via interacting with UBE2M and enhancing neddylation.

Experimental cell research

Zhao X,Jiang L,Hu D,Tang Y,Zhao G,Du X,Luo S,Tang W

Tue Jun 15 00:00:00 UTC 2021

Novel mutations in FSIP2 lead to multiple morphological abnormalities of the sperm flagella and poor ICSI prognosis.

Gene

Liu M,Sun Y,Li Y,Sun J,Yang Y,Shen Y

Thu May 20 00:00:00 UTC 2021

Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.

Neurobiology of disease

Zou L,Zhang X,Xiong M,Meng L,Tian Y,Pan L,Yuan X,Chen G,Wang Z,Bu L,Yao Z,Zhang Z,Ye K,Zhang Z

Thu Jul 01 00:00:00 UTC 2021

TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability.

Cell death & disease

Zhou S,Peng J,Xiao L,Zhou C,Fang Y,Ou Q,Qin J,Liu M,Pan Z,Hou Z

Sat May 08 00:00:00 UTC 2021

Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ.

Frontiers in cellular and infection microbiology

Yang S,Deng Q,Sun L,Zhu Y,Dong K,Wu S,Huang R,Li Y

Mon Jul 05 00:00:00 UTC 2021

Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.

Frontiers in cardiovascular medicine

Xu R,Kang L,Wei S,Yang C,Fu Y,Ding Z,Zou Y

Tue Oct 12 00:00:00 UTC 2021

Recognition of acetylated histone by Yaf9 regulates metabolic cycling of transcription initiation and chromatin regulatory factors.

Genes & development

Zhang J,Gundu A,Strahl BD

Wed Dec 01 00:00:00 UTC 2021

HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.

Frontiers in microbiology

Li X,Ma R,Wu B,Niu Y,Li H,Li D,Xie J,Idris A,Feng R

Wed Dec 15 00:00:00 UTC 2021

HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.

Frontiers in microbiology

Li X,Ma R,Wu B,Niu Y,Li H,Li D,Xie J,Idris A,Feng R

Wed Dec 15 00:00:00 UTC 2021

Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.

Bioengineered

Wang Q,Pan Y,Zhao L,Qi F,Liu J

Wed Dec 01 00:00:00 UTC 2021

G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer.

British journal of cancer

Zhao J,Fu X,Chen H,Min L,Sun J,Yin J,Guo J,Li H,Tang Z,Ruan Y,Wang X,Sun Y,Huang L

Fri Jan 01 00:00:00 UTC 2021

Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1-mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation.

British journal of pharmacology

Zhu X,Ye S,Yu D,Zhang Y,Li J,Zhang M,Leng Y,Yang T,Luo J,Chen X,Zhang H,Kong L

Wed Sep 01 00:00:00 UTC 2021

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.

The Journal of experimental medicine

Li K,Zheng X,Tang H,Zang YS,Zeng C,Liu X,Shen Y,Pang Y,Wang S,Xie F,Lu X,Luo Y,Li Z,Bi W,Jia X,Huang T,Wei R,Huang K,Chen Z,Zhu Q,He Y,Zhang M,Gu Z,Xiao Y,Zhang X,Fletcher JA,Wang Y

Mon Aug 02 00:00:00 UTC 2021

Structural insights into multifunctionality of human FACT complex subunit hSSRP1.

The Journal of biological chemistry

Li X,Li H,Jing Q,Wang M,Hu T,Li L,Zhang Q,Liu M,Fu YV,Han J,Su D

Wed Dec 01 00:00:00 UTC 2021

ITPRIP promotes glioma progression by linking MYL9 to DAPK1 inhibition.

Cellular signalling

Cao C,He K,Li S,Ge Q,Liu L,Zhang Z,Zhang H,Wang X,Sun X,Ding L

Wed Sep 01 00:00:00 UTC 2021

CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.

Cell death & disease

Zhang Y,Hou J,Shi S,Du J,Liu Y,Huang P,Li Q,Liu L,Hu H,Ji Y,Guo L,Shi Y,Liu Y,Cui H

Fri Jan 22 00:00:00 UTC 2021

Pathway of Hsp70 interactions at the ribosome.

Nature communications

Lee K,Ziegelhoffer T,Delewski W,Berger SE,Sabat G,Craig EA

Mon Sep 27 00:00:00 UTC 2021

Degradation of WTAP blocks antiviral responses by reducing the m⁶ A levels of IRF3 and IFNAR1 mRNA.

EMBO reports

Ge Y,Ling T,Wang Y,Jia X,Xie X,Chen R,Chen S,Yuan S,Xu A

Thu Nov 04 00:00:00 UTC 2021

Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.

Biochemical and biophysical research communications

Cai Y,Gu WT,Cheng K,Jia PF,Li F,Wang M,Zhang WF,Qiu JT,Wu ZB,Zhao WG

Fri Apr 23 00:00:00 UTC 2021

MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Cell death & disease

Tang J,Luo Y,Long G,Zhou L

Wed Oct 13 00:00:00 UTC 2021

MINDY1 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Cell death & disease

Tang J,Luo Y,Long G,Zhou L

Wed Oct 13 00:00:00 UTC 2021

Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.

American journal of physiology. Cell physiology

Peoples JN,Ghazal N,Duong DM,Hardin KR,Manning JR,Seyfried NT,Faundez V,Kwong JQ

Wed Sep 01 00:00:00 UTC 2021

LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.

Frontiers in cell and developmental biology

Gui Z,Zhao Z,Sun Q,Shao G,Huang J,Zhao W,Kuang Y

Fri Nov 19 00:00:00 UTC 2021

Pseudorabies Virus US3 Protein Inhibits IFN-β Production by Interacting With IRF3 to Block Its Activation.

Frontiers in microbiology

Xie J,Zhang X,Chen L,Bi Y,Idris A,Xu S,Li X,Zhang Y,Feng R

Wed Nov 10 00:00:00 UTC 2021

A novel CCDC39 mutation causes multiple morphological abnormalities of the flagella in a primary ciliary dyskinesia patient.

Reproductive biomedicine online

Chen D,Liang Y,Li J,Zhang X,Zheng R,Wang X,Zhang H,Shen Y

Mon Nov 01 00:00:00 UTC 2021

Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.

Cell death and differentiation

Zhang J,Chen Y,Chen X,Zhang W,Zhao L,Weng L,Tian H,Wu Z,Tan X,Ge X,Wang P,Fang L

Fri Jan 01 00:00:00 UTC 2021

A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis.

Open biology

Zhang W,Khan A,Vitale J,Neuner A,Rink K,Lüchtenborg C,Brügger B,Söllner TH,Schiebel E

Mon Nov 01 00:00:00 UTC 2021

Bacterial RF3 senses chaperone function in co-translational folding.

Molecular cell

Zhao L,Castanié-Cornet MP,Kumar S,Genevaux P,Hayer-Hartl M,Hartl FU

Thu Jul 15 00:00:00 UTC 2021

PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.

Cellular signalling

Li X,Sun L,Yan G,Yan X

Tue Jun 01 00:00:00 UTC 2021

TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer.

Autophagy

Zhou C,Liang Y,Zhou L,Yan Y,Liu N,Zhang R,Huang Y,Wang M,Tang Y,Ali DW,Wang Y,Michalak M,Chen XZ,Tang J

Fri Oct 01 00:00:00 UTC 2021

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.

Frontiers in cell and developmental biology

Zhao R,Liu Y,Wu C,Li M,Wei Y,Niu W,Yang J,Fan S,Xie Y,Li H,Wang W,Zeng Z,Xiong W,Li X,Li G,Zhou M

Sat Jun 12 00:00:00 UTC 2021

PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer.

Cancer letters

Jiang TY,Feng XF,Fang Z,Cui XW,Lin YK,Pan YF,Yang C,Ding ZW,Zhang YJ,Tan YX,Wang HY,Dong LW

Wed Mar 31 00:00:00 UTC 2021

The INO80 chromatin remodeling complex promotes thermomorphogenesis by connecting H2A.Z eviction and active transcription in Arabidopsis.

Molecular plant

Xue M,Zhang H,Zhao F,Zhao T,Li H,Jiang D

Mon Nov 01 00:00:00 UTC 2021

LHX9, a p53-binding protein, inhibits the progression of glioma by suppressing glycolysis.

Aging

Luo X,Ge J,Chen T,Liu J,Liu Z,Bi C,Lan S

Fri Sep 17 00:00:00 UTC 2021

Hypoxia-induced Tie1 drives stemness and cisplatin resistance in non-small cell lung carcinoma cells.

Cancer cell international

Li C,Yang N,Chen Z,Xia N,Shan Q,Wang Z,Lu J,Shang M,Wang Z

Mon Jan 18 00:00:00 UTC 2021

Glycogen accumulation and phase separation drives liver tumor initiation.

Cell

Liu Q,Li J,Zhang W,Xiao C,Zhang S,Nian C,Li J,Su D,Chen L,Zhao Q,Shao H,Zhao H,Chen Q,Li Y,Geng J,Hong L,Lin S,Wu Q,Deng X,Ke R,Ding J,Johnson RL,Liu X,Chen L,Zhou D

Thu Oct 28 00:00:00 UTC 2021

Curcumin analogue AI-44 alleviates MSU-induced gouty arthritis in mice via inhibiting cathepsin B-mediated NLRP3 inflammasome activation.

International immunopharmacology

Gu Y,Zhu Y,Deng G,Liu S,Sun Y,Lv W

Thu Apr 01 00:00:00 UTC 2021

Spodoptera frugiperda mRNA export factor interacts with and mediates the nuclear import of Autographa californica multiple nucleopolyhedrovirus ORF34 (Ac34).

Virus research

Tang Z,Luo W,Huang Z,Yuan M,Wu W,Yang K

Fri Jul 02 00:00:00 UTC 2021

FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation.

Cell death & disease

Liu X,Ge J,Chen C,Shen Y,Xie J,Zhu X,Liu M,Hu J,Chen L,Guo L,Zhou Q,Yan X,Qiu Y,Wan R,Marian AJ,Hong K

Tue Jan 05 00:00:00 UTC 2021

An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Cast TP,Boesch DJ,Smyth K,Shaw AE,Ghebrial M,Chanda S

Wed Jan 20 00:00:00 UTC 2021

Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization.

Nature communications

Zhang L,Zhang K,Zhang J,Zhu J,Xi Q,Wang H,Zhang Z,Cheng Y,Yang G,Liu H,Guo X,Zhou D,Xue Z,Li Y,Zhang Q,Da Y,Liu L,Yin Z,Yao Z,Zhang R

Wed Jul 14 00:00:00 UTC 2021

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.

International journal of biological sciences

Tang J,Tian Z,Liao X,Wu G

Fri Jan 14 00:00:00 UTC 2022

Calmodulin-dependent KCNE4 dimerization controls membrane targeting.

Scientific reports

Roig SR,Solé L,Cassinelli S,Colomer-Molera M,Sastre D,Serrano-Novillo C,Serrano-Albarrás A,Lillo MP,Tamkun MM,Felipe A

Wed Jul 07 00:00:00 UTC 2021

In vivo PCSK9 gene editing using an all-in-one self-cleavage AAV-CRISPR system.

Molecular therapy. Methods & clinical development

Li Q,Su J,Liu Y,Jin X,Zhong X,Mo L,Wang Q,Deng H,Yang Y

Fri Mar 12 00:00:00 UTC 2021

Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice.

Theranostics

Lin Y,Wang S,Gao L,Zhou Z,Yang Z,Lin J,Ren S,Xing H,Wu B

Thu Aug 05 00:00:00 UTC 2021

Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.

Veterinary microbiology

Zhu H,Yan J,Liu X,Li L,Liu W,Wang X,Jiang P,Bai J

Sat May 01 00:00:00 UTC 2021

Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms.

Veterinary microbiology

Zhu H,Yan J,Liu X,Li L,Liu W,Wang X,Jiang P,Bai J

Sat May 01 00:00:00 UTC 2021

Coexpression of HOXA6 and PBX2 promotes metastasis in gastric cancer.

Aging

Lin J,Zhu H,Hong L,Tang W,Wang J,Hu H,Wu X,Chen Y,Liu G,Yang Q,Li J,Wang Y,Lin Z,Xiao Y,Dai W,Huang M,Li G,Li A,Wang J,Xiang L,Liu S

Mon Feb 01 00:00:00 UTC 2021

Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer.

Cell death & disease

Sun Y,Ren D,Zhou Y,Shen J,Wu H,Jin X

Sat Sep 25 00:00:00 UTC 2021

SENP3 Promotes an Mff-Primed Bcl-x -Drp1 Interaction Involved in Cell Death Following Ischemia.

Frontiers in cell and developmental biology

Guo C,Hildick KL,Jiang J,Zhao A,Guo W,Henley JM,Wilkinson KA

Tue Nov 02 00:00:00 UTC 2021

De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.

Brain : a journal of neurology

Shireman JM,Atashi F,Lee G,Ali ES,Saathoff MR,Park CH,Savchuk S,Baisiwala S,Miska J,Lesniak MS,James CD,Stupp R,Kumthekar P,Horbinski CM,Ben-Sahra I,Ahmed AU

Fri May 07 00:00:00 UTC 2021

Novel clerodane-type diterpenoid Cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6.

Pharmacological research

Di Q,Zhao X,Zhang R,Ma X,Liang X,Li X,Gao J,Tang H,Chen W,Xiao W

Mon Feb 01 00:00:00 UTC 2021

RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.

DNA and cell biology

Zhou M,Chen X,Bai H,Sun Y,Zhang Z,Li S,Wang X,Zeng M

Mon Nov 01 00:00:00 UTC 2021

Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice.

Journal of neuroinflammation

Cao LL,Guan PP,Zhang SQ,Yang Y,Huang XS,Wang P

Fri Dec 03 00:00:00 UTC 2021

Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice.

Journal of neuroinflammation

Cao LL,Guan PP,Zhang SQ,Yang Y,Huang XS,Wang P

Fri Dec 03 00:00:00 UTC 2021

Atp23p and Atp10p coordinate to regulate the assembly of yeast mitochondrial ATP synthase.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yang G,Ding Y,Shang X,Zhao T,Lu S,Tian J,Weng J,Zeng X

Tue Jun 01 00:00:00 UTC 2021

SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1.

Frontiers in immunology

Sui L,Zhao Y,Wang W,Wu P,Wang Z,Yu Y,Hou Z,Tan G,Liu Q

Tue Jun 15 00:00:00 UTC 2021

A novel mutation in DNAH17 is present in a patient with multiple morphological abnormalities of the flagella.

Reproductive biomedicine online

Zheng R,Sun Y,Jiang C,Chen D,Yang Y,Shen Y

Wed Sep 01 00:00:00 UTC 2021

Nedd4-2 haploinsufficiency in mice causes increased seizure susceptibility and impaired Kir4.1 ubiquitination.

Biochimica et biophysica acta. Molecular basis of disease

Liu X,Zhang H,Zhang B,Tu J,Li X,Zhao Y

Tue Jun 01 00:00:00 UTC 2021

RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.

Cell death & disease

Feng X,Jiang T,Yang C,Pang S,Ding Z,Hu H,Wang H,Dong L,Yang N

Fri Dec 17 00:00:00 UTC 2021

Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.

Cell stem cell

Le R,Huang Y,Zhang Y,Wang H,Lin J,Dong Y,Li Z,Guo M,Kou X,Zhao Y,Chen M,Zhu Q,Zhao A,Yin J,Sun J,Su Z,Shi K,Gao Y,Chen J,Liu W,Kang L,Wang Y,Li C,Liu X,Gao R,Wang H,Ju Z,Gao S

Thu Apr 01 00:00:00 UTC 2021

Whole-exome sequencing of de novo genetic variants in a Chinese family with a sporadic case of congenital nonsyndromic hearing loss.

F1000Research

Hu S,Zhang H,Liu Y,Liu M,Li J,Liao S

Thu Oct 21 00:00:00 UTC 2021

Whole-exome sequencing of de novo genetic variants in a Chinese family with a sporadic case of congenital nonsyndromic hearing loss.

F1000Research

Hu S,Zhang H,Liu Y,Liu M,Li J,Liao S

Thu Oct 21 00:00:00 UTC 2021

Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.

Cell death & disease

Zhou W,Zhong Z,Lin D,Liu Z,Zhang Q,Xia H,Peng S,Liu A,Lu Z,Wang Y,Ye S,Ye Q

Wed Feb 24 00:00:00 UTC 2021

Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.

Proceedings of the National Academy of Sciences of the United States of America

Hsu JC,Laurent-Rolle M,Pawlak JB,Wilen CB,Cresswell P

Tue Jun 15 00:00:00 UTC 2021

TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection.

Nature communications

Geng J,Shi Y,Zhang J,Yang B,Wang P,Yuan W,Zhao H,Li J,Qin F,Hong L,Xie C,Deng X,Sun Y,Wu C,Chen L,Zhou D

Thu Jun 10 00:00:00 UTC 2021

Glutaredoxins regulate maize inflorescence meristem development via redox control of TGA transcriptional activity.

Nature plants

Yang RS,Xu F,Wang YM,Zhong WS,Dong L,Shi YN,Tang TJ,Sheng HJ,Jackson D,Yang F

Wed Dec 01 00:00:00 UTC 2021

Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis.

Virologica Sinica

Li P,Jiang H,Peng H,Zeng W,Zhong Y,He M,Xie L,Chen J,Guo D,Wu J,Li CM

Wed Dec 01 00:00:00 UTC 2021

The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.

Frontiers in immunology

Tang T,Li P,Zhou X,Wang R,Fan X,Yang M,Qi K

Wed Jan 05 00:00:00 UTC 2022

The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3.

Frontiers in immunology

Tang T,Li P,Zhou X,Wang R,Fan X,Yang M,Qi K

Wed Jan 05 00:00:00 UTC 2022

CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.

Experimental cell research

Yang Y,Zou P,He L,Shao J,Tang Y,Li J

Sun Aug 15 00:00:00 UTC 2021

An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development.

Journal of experimental & clinical cancer research : CR

Wang R,Liu J,Li K,Yang G,Chen S,Wu J,Xie X,Ren H,Pang Y

Wed Oct 13 00:00:00 UTC 2021

Mucosal IgA response elicited by intranasal immunization of Lactobacillus plantarum expressing surface-displayed RBD protein of SARS-CoV-2.

International journal of biological macromolecules

Li L,Wang M,Hao J,Han J,Fu T,Bai J,Tian M,Jin N,Zhu G,Li C

Mon Nov 01 00:00:00 UTC 2021

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer.

Clinical and translational medicine

Lu C,Qiao P,Sun Y,Ren C,Yu Z

Thu Apr 01 00:00:00 UTC 2021

Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer.

Clinical and translational medicine

Lu C,Qiao P,Sun Y,Ren C,Yu Z

Thu Apr 01 00:00:00 UTC 2021

Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.

MedComm

Li Y,Su Y,Zhao Y,Hu X,Zhao G,He J,Wan S,Lü M,Cui H

Wed Sep 01 00:00:00 UTC 2021

Human VAMP3 Suppresses or Negatively Regulates Bax Induced Apoptosis in Yeast.

Biomedicines

Akintade DD,Chaudhuri B

Tue Jan 19 00:00:00 UTC 2021

Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.

International journal of biological macromolecules

Hou Z,Shi W,Feng J,Wang W,Zheng E,Lin H,Yu C,Li L

Wed Jun 30 00:00:00 UTC 2021

MITOL promotes cell survival by degrading Parkin during mitophagy.

EMBO reports

Shiiba I,Takeda K,Nagashima S,Ito N,Tokuyama T,Yamashita SI,Kanki T,Komatsu T,Urano Y,Fujikawa Y,Inatome R,Yanagi S

Wed Mar 03 00:00:00 UTC 2021

CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.

Molecular cancer

Fan Y,Wang J,Jin W,Sun Y,Xu Y,Wang Y,Liang X,Su D

Tue Feb 02 00:00:00 UTC 2021

CTRP1 Aggravates Cardiac Dysfunction Post Myocardial Infarction by Modulating TLR4 in Macrophages.

Frontiers in immunology

Gu Y,Hu X,Ge PB,Chen Y,Wu S,Zhang XW

Tue Sep 21 00:00:00 UTC 2021

Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang H,Xia Y,Wang F,Luo M,Yang K,Liang S,An S,Wu S,Yang C,Chen D,Xu M,Cai M,To KKW,Fu L

Sat May 01 00:00:00 UTC 2021

OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.

Cell death & disease

Tang J,Wu Z,Tian Z,Chen W,Wu G

Tue May 25 00:00:00 UTC 2021

A novel function of African Swine Fever Virus pE66L in inhibition of host translation by the PKR/eIF2α pathway.

Journal of virology

Shen Z,Chen C,Yang Y,Xie Z,Ao Q,Lv L,Zhang S,Chen H,Hu R,Chen H,Peng G

Mon Mar 01 00:00:00 UTC 2021

MINDY1 promotes bladder cancer progression by stabilizing YAP.

Cancer cell international

Luo Y,Zhou J,Tang J,Zhou F,He Z,Liu T,Liu T

Tue Jul 27 00:00:00 UTC 2021

The novel interaction mode among centromere sub-complex CENP-O/P/U/Q/R.

Journal of molecular recognition : JMR

Cao B,Zhao C,Zhang Y,Wang X,Ye J,Hu L,He X

Sun Aug 01 00:00:00 UTC 2021

The novel interaction mode among centromere sub-complex CENP-O/P/U/Q/R.

Journal of molecular recognition : JMR

Cao B,Zhao C,Zhang Y,Wang X,Ye J,Hu L,He X

Sun Aug 01 00:00:00 UTC 2021

Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation.

Redox biology

Yee YH,Chong SJF,Kong LR,Goh BC,Pervaiz S

Sat May 01 00:00:00 UTC 2021

ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.

Biochemical and biophysical research communications

Zhang X,Tang L,Zhang Z

Fri Jan 22 00:00:00 UTC 2021

Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival.

Frontiers in immunology

Cheng B,Li X,Dai K,Duan S,Rong Z,Chen Y,Lü L,Liu Z,Huang X,Xu H,Zhang YW,Zheng H

Thu Sep 16 00:00:00 UTC 2021

TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.

Cell death & disease

Hu J,Ding X,Tian S,Chu Y,Liu Z,Li Y,Li X,Wang G,Wang L,Wang Z

Mon Apr 12 00:00:00 UTC 2021

TRIM15 promotes the invasion and metastasis of pancreatic cancer cells by mediating APOA1 ubiquitination and degradation.

Biochimica et biophysica acta. Molecular basis of disease

Sun Y,Ren D,Yang C,Yang W,Zhao J,Zhou Y,Jin X,Wu H

Mon Nov 01 00:00:00 UTC 2021

Heat shock protein 70, glutamate dehydrogenase, and angiotensin-converting enzyme of Bombyx mori mediate the cell attachment of Cypovirus 1.

The Journal of general virology

Yang J,Wang J,Peng X,Lei C,Sun X,Hu J

Wed Dec 01 00:00:00 UTC 2021

CUL5-ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy.

Frontiers in cell and developmental biology

Gong L,Wang K,Wang M,Hu R,Li H,Gao D,Lin M

Fri Jun 25 00:00:00 UTC 2021

RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.

Cell

Rheinemann L,Downhour DM,Bredbenner K,Mercenne G,Davenport KA,Schmitt PT,Necessary CR,McCullough J,Schmitt AP,Simon SM,Sundquist WI,Elde NC

Thu Oct 14 00:00:00 UTC 2021

E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis.

Cell death and differentiation

Mei P,Xie F,Pan J,Wang S,Gao W,Ge R,Gao B,Gao S,Chen X,Wang Y,Wu J,Ding C,Li J

Fri Oct 01 00:00:00 UTC 2021

Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ.

Science advances

Chen C,Xu Q,Zhang Y,Davies BA,Huang Y,Katzmann DJ,Harris PC,Hu J,Ling K

Tue Jun 01 00:00:00 UTC 2021

Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma.

Aging

Peng Y,Zhang Z,Zhang A,Liu C,Sun Y,Peng Z,Liu Y

Wed Mar 24 00:00:00 UTC 2021

Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2.

Cancer letters

Si W,Zhou B,Xie W,Li H,Li K,Li S,Deng W,Shi P,Yuan C,Ke T,Ren X,Tu X,Zeng X,Weigelt B,Rubin BP,Chen Q,Xu C,Wang QK

Thu Jan 28 00:00:00 UTC 2021

EGY3 mediates chloroplastic ROS homeostasis and promotes retrograde signaling in response to salt stress in Arabidopsis.

Cell reports

Zhuang Y,Wei M,Ling C,Liu Y,Amin AK,Li P,Li P,Hu X,Bao H,Huo H,Smalle J,Wang S

Tue Jul 13 00:00:00 UTC 2021

Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.

International journal of biological macromolecules

Yang Z,Ouyang T,Aoyagi H,Wang T,Xing X,Zhang Y,Wang Y,Li Y,Aizaki H,Li S,Kong L

Fri Oct 01 00:00:00 UTC 2021

Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.

International journal of biological macromolecules

Yang Z,Ouyang T,Aoyagi H,Wang T,Xing X,Zhang Y,Wang Y,Li Y,Aizaki H,Li S,Kong L

Fri Oct 01 00:00:00 UTC 2021

A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling.

Journal of biomedical science

Fang CH,Lin YT,Liang CM,Liang SM

Fri Mar 13 00:00:00 UTC 2020

A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling.

Journal of biomedical science

Fang CH,Lin YT,Liang CM,Liang SM

Fri Mar 13 00:00:00 UTC 2020

MICAL-L2 Is Essential for c-Myc Deubiquitination and Stability in Non-small Cell Lung Cancer Cells.

Frontiers in cell and developmental biology

Min P,Zhang L,Wang Y,Qi C,Song Y,Bibi M,Zhang Y,Ma Y,Zhao X,Yu M,Du J

Tue Feb 02 00:00:00 UTC 2021

Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis.

Molecular biology reports

Akintade DD,Chaudhuri B

Tue Sep 01 00:00:00 UTC 2020

Astragalus membranaceus-Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors.

BioMed research international

Chang FL,Tsai KC,Lin TY,Yang TW,Lo YN,Chen WC,Chang JH,Lu MK,Chiou CT,Chen PH,Yen Y,Pan SL,Lee YC

Mon Dec 07 00:00:00 UTC 2020

The BRCC3 regulated by Cdk5 promotes the activation of neuronal NLRP3 inflammasome in Parkinson's disease models.

Biochemical and biophysical research communications

Cheng X,Xu S,Zhang C,Qin K,Yan J,Shao X

Wed Feb 12 00:00:00 UTC 2020

Virus-induced p38 MAPK activation facilitates viral infection.

Theranostics

Cheng Y,Sun F,Wang L,Gao M,Xie Y,Sun Y,Liu H,Yuan Y,Yi W,Huang Z,Yan H,Peng K,Wu Y,Cao Z

Fri Dec 11 00:00:00 UTC 2020

EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Choi HH,Zou S,Wu JL,Wang H,Phan L,Li K,Zhang P,Chen D,Liu Q,Qin B,Nguyen TAT,Yeung SJ,Fang L,Lee MH

Thu Oct 01 00:00:00 UTC 2020

Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models.

Nature communications

Lee PT,Liévens JC,Wang SM,Chuang JY,Khalil B,Wu HE,Chang WC,Maurice T,Su TP

Wed Nov 04 00:00:00 UTC 2020

Identification of host protein CBL interacting with Eimeria acervulina microneme protein MIC3.

Acta biochimica et biophysica Sinica

Wang P,Zhao H,Wang Q,Gao C,Wu H,Cheng C,Song H

Tue Sep 08 00:00:00 UTC 2020

Identification of host protein CBL interacting with Eimeria acervulina microneme protein MIC3.

Acta biochimica et biophysica Sinica

Wang P,Zhao H,Wang Q,Gao C,Wu H,Cheng C,Song H

Tue Sep 08 00:00:00 UTC 2020

Typical Stress Granule Proteins Interact with the 3' Untranslated Region of Enterovirus D68 To Inhibit Viral Replication.

Journal of virology

Cheng J,Gao S,Zhu C,Liu S,Li J,Kang J,Wang Z,Wang T

Tue Mar 17 00:00:00 UTC 2020

NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway.

Cell death & disease

Ma X,Qiu Y,Sun Y,Zhu L,Zhao Y,Li T,Lin Y,Ma D,Qin Z,Sun C,Han L

Fri Mar 06 00:00:00 UTC 2020

SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma.

Theranostics

Xu H,Wang H,Zhao W,Fu S,Li Y,Ni W,Xin Y,Li W,Yang C,Bai Y,Zhan M,Lu L

Mon Aug 02 00:00:00 UTC 2021

PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval.

Cell reports

Yong XLH,Cousin MA,Anggono V

Tue Oct 27 00:00:00 UTC 2020

RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.

Molecular cell

Hu X,Wang L,Wang Y,Ji J,Li J,Wang Z,Li C,Zhang Y,Zhang ZR

Thu Jul 16 00:00:00 UTC 2020

Ligand-dependent internalization of Bombyx mori tachykinin-related peptide receptor is regulated by PKC, GRK5 and β-arrestin2/BmKurtz.

Biochimica et biophysica acta. Molecular cell research

He X,Yan L,Wu Q,Zhang G,Zhou N

Mon Jun 01 00:00:00 UTC 2020

Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.

Viruses

Shen Z,Yang Y,Yang S,Zhang G,Xiao S,Fu ZF,Peng G

Tue Jul 28 00:00:00 UTC 2020

SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation.

American journal of cancer research

Yuan D,Chen Y,Yang Z,Li G,Wu M,Jiang J,Li D,Yu Q

Mon Sep 28 00:00:00 UTC 2020

Cholesterol 25-hydroxylase inhibits encephalomyocarditis virus replication through enzyme activity-dependent and independent mechanisms.

Veterinary microbiology

Li S,Li L,Zhu H,Shi M,Fan H,Gao Y,Wang X,Jiang P,Bai J

Mon Jun 01 00:00:00 UTC 2020

lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.

Molecular therapy. Nucleic acids

Liu C,Peng Z,Li P,Fu H,Feng J,Zhang Y,Liu T,Liu Y,Liu Q,Liu Q,Li D,Wu M

Fri Mar 06 00:00:00 UTC 2020

Apoptosis, Induced by Human α-Synuclein in Yeast, Can Occur Independent of Functional Mitochondria.

Cells

Akintade DD,Chaudhuri B

Tue Sep 29 00:00:00 UTC 2020

USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin.

Oncology letters

Lin Y,Zhong H,Sun B,Peng Y,Lu F,Chen M,Zhu M,Huang J

Sun Nov 01 00:00:00 UTC 2020

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).

Cells

Zhao Y,Lei Y,He SW,Li YQ,Wang YQ,Hong XH,Liang YL,Li JY,Chen Y,Luo WJ,Zhang PP,Yang XJ,He QM,Ma J,Liu N,Tang LL

Thu Feb 27 00:00:00 UTC 2020

ADAMTS-1 and syndecan-4 intersect in the regulation of cell migration and angiogenesis.

Journal of cell science

Lambert J,Makin K,Akbareian S,Johnson R,Alghamdi AAA,Robinson SD,Edwards DR

Wed Apr 08 00:00:00 UTC 2020

Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.

Nature communications

Bagchi P,Torres M,Qi L,Tsai B

Fri Feb 28 00:00:00 UTC 2020

Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.

Nature communications

Bagchi P,Torres M,Qi L,Tsai B

Fri Feb 28 00:00:00 UTC 2020

FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.

Journal of molecular biology

Yang J,Gong Z,Lu YB,Xu CJ,Wei TF,Yang MS,Zhan TW,Yang YH,Lin L,Liu J,Tang C,Zhang WP

Fri Jul 24 00:00:00 UTC 2020

A recombinant Lactobacillus plantarum strain expressing the spike protein of SARS-CoV-2.

International journal of biological macromolecules

Wang M,Fu T,Hao J,Li L,Tian M,Jin N,Ren L,Li C

Thu Oct 01 00:00:00 UTC 2020

Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance.

Cancer research

Zheng ZQ,Li ZX,Guan JL,Liu X,Li JY,Chen Y,Lin L,Kou J,Lv JW,Zhang LL,Zhou GQ,Liu RQ,Chen F,He XJ,Li YQ,Li F,Xu SS,Ma J,Liu N,Sun Y

Tue Dec 01 00:00:00 UTC 2020

Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.

Scientific reports

Zhang Z,Wang Y,Shan Y,Zhou R,Yin W

Fri Nov 06 00:00:00 UTC 2020

Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.

Oncogene

Feng J,Zhang Y,Ren X,Li D,Fu H,Liu C,Zhou W,Liu Q,Liu Q,Wu M

Mon Jun 01 00:00:00 UTC 2020

USP1 Maintains the Survival of Liver Circulating Tumor Cells by Deubiquitinating and Stabilizing TBLR1.

Frontiers in oncology

Li Y,Xu Y,Gao C,Sun Y,Zhou K,Wang P,Cheng J,Guo W,Ya C,Fan J,Yang X

Wed Oct 28 00:00:00 UTC 2020

Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.

Communications biology

Reimann L,Schwäble AN,Fricke AL,Mühlhäuser WWD,Leber Y,Lohanadan K,Puchinger MG,Schäuble S,Faessler E,Wiese H,Reichenbach C,Knapp B,Peikert CD,Drepper F,Hahn U,Kreutz C,van der Ven PFM,Radziwill G,Djinović-Carugo K,Fürst DO,Warscheid B

Fri May 22 00:00:00 UTC 2020

UCHL1 regulates oxidative activity in skeletal muscle.

PloS one

Gao H,Antony R,Srinivasan R,Wu P,Wang X,Li Y

Tue Dec 29 00:00:00 UTC 2020

DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway.

Journal of genetics and genomics = Yi chuan xue bao

Liu L,Liu W,Shi Y,Li L,Gao Y,Lei Y,Finnell R,Zhang T,Zhang F,Jin L,Li H,Tao W,Wang H

Sat Jun 20 00:00:00 UTC 2020

Snail promotes prostate cancer migration by facilitating SPOP ubiquitination and degradation.

Biochemical and biophysical research communications

Lv W,Huan M,Yang W,Gao Y,Wang K,Xu S,Zhang M,Ma J,Wang X,Chen Y,Li L

Thu Aug 27 00:00:00 UTC 2020

HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer.

Oncogene

Wang J,He C,Gao P,Wang S,Lv R,Zhou H,Zhou Q,Zhang K,Sun J,Fan C,Ding G,Lan F

Sat Feb 01 00:00:00 UTC 2020

LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.

Molecular cancer

Zhou C,Yi C,Yi Y,Qin W,Yan Y,Dong X,Zhang X,Huang Y,Zhang R,Wei J,Ali DW,Michalak M,Chen XZ,Tang J

Wed Jul 29 00:00:00 UTC 2020

The casein kinase 2α promotes the occurrence polycystic ovary syndrome.

Biochemical and biophysical research communications

Yu CJ,Liu X,Zhou ZY,Chen XJ,Meng YC,Gu HC,Xu JJ,Ding GL,Liu XM,Sheng JZ,Huang HF

Mon Feb 17 00:00:00 UTC 2020

PRV-encoded UL13 protein kinase acts as an antagonist of innate immunity by targeting IRF3-signaling pathways.

Veterinary microbiology

Lv L,Cao M,Bai J,Jin L,Wang X,Gao Y,Liu X,Jiang P

Sun Nov 01 00:00:00 UTC 2020

HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling.

Redox biology

Zhou Y,Wang K,Zhou Y,Li T,Yang M,Wang R,Chen Y,Cao M,Hu R

Wed Jan 01 00:00:00 UTC 2020

Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity.

Viruses

Chesarino NM,Emerman M

Mon Mar 30 00:00:00 UTC 2020

Costunolide represses hepatic fibrosis through WW domain-containing protein 2-mediated Notch3 degradation.

British journal of pharmacology

Ge MX,Liu HT,Zhang N,Niu WX,Lu ZN,Bao YY,Huang R,Yu DK,Shao RG,He HW

Wed Jan 01 00:00:00 UTC 2020

A Novel Nonsense GLI3 Variant Is Associated With Polydactyly and Syndactyly in a Family by Blocking the Sonic Hedgehog Signaling Pathway.

Frontiers in genetics

Xiang Y,Li X,Zhan Z,Feng J,Cai H,Li Y,Fu Q,Xu Y,Jiang H,Zhang X

Sat Dec 12 00:00:00 UTC 2020

TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.

Neoplasia (New York, N.Y.)

Tang J,Luo Y,Tian Z,Liao X,Cui Q,Yang Q,Wu G

Tue Sep 01 00:00:00 UTC 2020

Construction and optimization of Lactobacillus plantarum expression system expressing glycoprotein 5 of porcine reproductive and respiratory syndrome virus.

International journal of biological macromolecules

Wang M,Du S,Xu W,Song L,Hao P,Jin N,Ren L,Li C

Wed Jan 15 00:00:00 UTC 2020

AcMNPV PKIP is required for hyperexpression of very late genes and involved in the hyperphosphorylation of the viral basic protein P6.9.

Virus research

Lai Q,Xu L,Wang Y,Luo W,Zhu L,Yuan M,Wu W,Yang K

Thu Apr 02 00:00:00 UTC 2020

G250 Antigen-Targeting Drug-Loaded Nanobubbles Combined with Ultrasound Targeted Nanobubble Destruction: A Potential Novel Treatment for Renal Cell Carcinoma.

International journal of nanomedicine

Yu Z,Wang Y,Xu D,Zhu L,Hu M,Liu Q,Lan W,Jiang J,Wang L

Tue May 12 00:00:00 UTC 2020

Cardiolipin, conformation, and respiratory complex-dependent oligomerization of the major mitochondrial ADP/ATP carrier in yeast.

Science advances

Senoo N,Kandasamy S,Ogunbona OB,Baile MG,Lu Y,Claypool SM

Sat Aug 01 00:00:00 UTC 2020

Porcine reproductive and respiratory syndrome virus Nsp4 cleaves ZAP to antagonize its antiviral activity.

Veterinary microbiology

Zhao Y,Song Z,Bai J,Liu X,Nauwynck H,Jiang P

Sun Nov 01 00:00:00 UTC 2020

STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.

Autophagy

Zhou C,Qian X,Hu M,Zhang R,Liu N,Huang Y,Yang J,Zhang J,Bai H,Yang Y,Wang Y,Ali D,Michalak M,Chen XZ,Tang J

Thu Oct 01 00:00:00 UTC 2020

Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.

Journal of experimental & clinical cancer research : CR

Li C,Deng C,Pan G,Wang X,Zhang K,Dong Z,Zhao G,Tan M,Hu X,Shi S,Du J,Ji H,Wang X,Yang L,Cui H

Fri Oct 30 00:00:00 UTC 2020

Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.

Cell proliferation

Sun Q,Fan G,Zhuo Q,Dai W,Ye Z,Ji S,Xu W,Liu W,Hu Q,Zhang Z,Liu M,Yu X,Xu X,Qin Y

Fri May 01 00:00:00 UTC 2020

Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.

Cell proliferation

Sun Q,Fan G,Zhuo Q,Dai W,Ye Z,Ji S,Xu W,Liu W,Hu Q,Zhang Z,Liu M,Yu X,Xu X,Qin Y

Fri May 01 00:00:00 UTC 2020

MKL-1 is a coactivator for STAT5b, the regulator of Treg cell development and function.

Cell communication and signaling : CCS

Xiang Y,Wang J,Li JP,Guo W,Huang F,Zhang HM,Li HH,Dai ZT,Zhang ZJ,Li H,Bao LY,Gu CJ,Chen K,Zhang TC,Liao XH

Thu Jul 09 00:00:00 UTC 2020

Peroxisome proliferator-activated receptor γ isoforms differentially regulate preadipocyte proliferation, apoptosis, and differentiation in chickens.

Poultry science

Mu F,Jing Y,Ning B,Huang J,Cui T,Guo Y,You X,Yan X,Li H,Wang N

Tue Dec 01 00:00:00 UTC 2020

IU1 suppresses proliferation of cervical cancer cells through MDM2 degradation.

International journal of biological sciences

Xu L,Wang J,Yuan X,Yang S,Xu X,Li K,He Y,Wei L,Zhang J,Tian Y

Mon Apr 04 00:00:00 UTC 2022

RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.

Drug design, development and therapy

Yu X,Yang F,Jiang H,Fan L

Tue Dec 22 00:00:00 UTC 2020

NOD1 inhibits proliferation and enhances response to chemotherapy via suppressing SRC-MAPK pathway in hepatocellular carcinoma.

Journal of molecular medicine (Berlin, Germany)

Ma X,Qiu Y,Zhu L,Zhao Y,Lin Y,Ma D,Qin Z,Sun C,Shen X,Li T,Han L

Sat Feb 01 00:00:00 UTC 2020

TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2.

Protein & cell

Sun N,Jiang L,Ye M,Wang Y,Wang G,Wan X,Zhao Y,Wen X,Liang L,Ma S,Liu L,Bu Z,Chen H,Li C

Tue Dec 01 00:00:00 UTC 2020

PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6.

Brain, behavior, and immunity

Han C,Yan P,He T,Cheng J,Zheng W,Zheng LT,Zhen X

Sat Aug 01 00:00:00 UTC 2020

The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.

Cell death and differentiation

Zhu L,Qin C,Li T,Ma X,Qiu Y,Lin Y,Ma D,Qin Z,Sun C,Shen X,Zhao Y,Han L

Mon Jun 01 00:00:00 UTC 2020

Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.

Nature communications

Wang Y,Zhan Q,Wang X,Li P,Liu S,Gao G,Gao P

Tue Jun 02 00:00:00 UTC 2020

Espin distribution as revealed by super-resolution microscopy of stereocilia.

American journal of translational research

Qi J,Zhang L,Tan F,Liu Y,Chu C,Zhu W,Wang Y,Qi Z,Chai R

Mon Sep 28 00:00:00 UTC 2020

APC2^CDH1 negatively regulates agrin signaling by promoting the ubiquitination and proteolytic degradation of DOK7.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chen A,Bai L,Zhong K,Shu X,Wang A,Xiao Y,Zhang K,Shen C

Tue Sep 01 00:00:00 UTC 2020

PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.

Science translational medicine

Jiang TY,Pan YF,Wan ZH,Lin YK,Zhu B,Yuan ZG,Ma YH,Shi YY,Zeng TM,Dong LW,Tan YX,Wang HY

Wed Sep 23 00:00:00 UTC 2020

SETDB2 promoted breast cancer stem cell maintenance by interaction with and stabilization of ΔNp63α protein.

International journal of biological sciences

Ying L,Fei X,Jialun L,Jianpeng X,Jie W,Zhaolin M,Hongjia F,Huan F,Sha L,Qiuju W,Lin Y,Cuicui L,You P,Weiwei Z,Lulu W,Jiemin W,Jing L,Jing F

Mon Nov 15 00:00:00 UTC 2021

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.

Cell

Trendel J,Schwarzl T,Horos R,Prakash A,Bateman A,Hentze MW,Krijgsveld J

Thu Jan 10 00:00:00 UTC 2019

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.

Cell

Trendel J,Schwarzl T,Horos R,Prakash A,Bateman A,Hentze MW,Krijgsveld J

Thu Jan 10 00:00:00 UTC 2019

PDCD5 regulates iNKT cell terminal maturation and iNKT1 fate decision.

Cellular & molecular immunology

Wang K,Zhang X,Wang Y,Jin G,Li M,Zhang S,Hao J,Jin R,Huang X,Wu H,Zhang J,Chen Y,Ge Q

Sun Sep 01 00:00:00 UTC 2019

PDCD5 regulates iNKT cell terminal maturation and iNKT1 fate decision.

Cellular & molecular immunology

Wang K,Zhang X,Wang Y,Jin G,Li M,Zhang S,Hao J,Jin R,Huang X,Wu H,Zhang J,Chen Y,Ge Q

Sun Sep 01 00:00:00 UTC 2019

Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing.

Nucleic acids research

Lu B,Javidi-Parsijani P,Makani V,Mehraein-Ghomi F,Sarhan WM,Sun D,Yoo KW,Atala ZP,Lyu P,Atala A

Tue May 07 00:00:00 UTC 2019

Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination.

Neuron

Liu Z,Yan M,Liang Y,Liu M,Zhang K,Shao D,Jiang R,Li L,Wang C,Nussenzveig DR,Zhang K,Chen S,Zhong C,Mo W,Fontoura BMA,Zhang L

Wed May 08 00:00:00 UTC 2019

Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment.

Oncogene

Feng J,Zhang Y,She X,Sun Y,Fan L,Ren X,Fu H,Liu C,Li P,Zhao C,Liu Q,Liu Q,Li G,Wu M

Tue Jan 01 00:00:00 UTC 2019

Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment.

Oncogene

Feng J,Zhang Y,She X,Sun Y,Fan L,Ren X,Fu H,Liu C,Li P,Zhao C,Liu Q,Liu Q,Li G,Wu M

Tue Jan 01 00:00:00 UTC 2019

Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by YBX2 via its interaction with YBX2†.

Biology of reproduction

He Y,Lin Y,Zhu Y,Ping P,Wang G,Sun F

Fri Feb 01 00:00:00 UTC 2019

Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by YBX2 via its interaction with YBX2†.

Biology of reproduction

He Y,Lin Y,Zhu Y,Ping P,Wang G,Sun F

Fri Feb 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.

Cellular microbiology

Wang C,Fu J,Wang M,Cai Y,Hua X,Du Y,Yang Z,Li Y,Wang Z,Sheng H,Yin N,Liu X,Koehler JE,Yuan C

Mon Apr 01 00:00:00 UTC 2019

Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast.

Bioorganic & medicinal chemistry letters

Derf A,Sharma A,Bharate SB,Chaudhuri B

Fri Feb 01 00:00:00 UTC 2019

Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast.

Bioorganic & medicinal chemistry letters

Derf A,Sharma A,Bharate SB,Chaudhuri B

Fri Feb 01 00:00:00 UTC 2019

Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress.

Proceedings of the National Academy of Sciences of the United States of America

Igbaria A,Merksamer PI,Trusina A,Tilahun F,Johnson JR,Brandman O,Krogan NJ,Weissman JS,Papa FR

Tue Jun 04 00:00:00 UTC 2019

Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome.

Frontiers in molecular neuroscience

Chang HY,Cheng HY,Tsao AN,Liu C,Tsai JW

Tue Sep 29 00:00:00 UTC 2020

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

Biochemical pharmacology

Chen M,Guo L,Dong D,Yu F,Zhang T,Wu B

Fri Mar 01 00:00:00 UTC 2019

PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.

Viruses

Wu F,Niu Z,Zhou B,Li P,Qian F

Thu Jan 24 00:00:00 UTC 2019

A long noncoding RNA cluster-based genomic locus maintains proper development and visual function.

Nucleic acids research

Wang F,Ren D,Liang X,Ke S,Zhang B,Hu B,Song X,Wang X

Tue Jul 09 00:00:00 UTC 2019

Construction, expression and antiviral activity analysis of recombinant adenovirus expressing human IFITM3 in vitro.

International journal of biological macromolecules

Du S,Jiang Y,Xu W,Bai J,Tian M,Wang M,Wang Y,Cao T,Song L,Jiang Y,Chen J,Fu T,Hao P,Li T,Wu S,Ren L,Jin N,Li C

Sat Jun 15 00:00:00 UTC 2019

A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA.

mBio

Park HJ,Wang W,Curlango-Rivera G,Xiong Z,Lin Z,Huskey DA,Hawes MC,VanEtten HD,Turgeon BG

Tue Mar 05 00:00:00 UTC 2019

ZAP, a CCCH-Type Zinc Finger Protein, Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication and Interacts with Viral Nsp9.

Journal of virology

Zhao Y,Song Z,Bai J,Liu X,Nauwynck H,Jiang P

Wed May 15 00:00:00 UTC 2019

APOBEC3G is a restriction factor of EV71 and mediator of IMB-Z antiviral activity.

Antiviral research

Wang H,Zhong M,Li Y,Li K,Wu S,Guo T,Cen S,Jiang J,Li Z,Li Y

Wed May 01 00:00:00 UTC 2019

Inhibition of tankyrase by a novel small molecule significantly attenuates prostate cancer cell proliferation.

Cancer letters

Cheng H,Li X,Wang C,Chen Y,Li S,Tan J,Tan B,He Y

Thu Feb 28 00:00:00 UTC 2019

Novel interactions between ERα-36 and STAT3 mediate breast cancer cell migration.

Cell communication and signaling : CCS

Xiang Y,Li JP,Guo W,Wang DQ,Yao A,Zhang HM,Huang F,Li HH,Dai ZT,Zhang ZJ,Li H,Tan Y,Chen K,Bao LY,Liao XH

Tue Aug 13 00:00:00 UTC 2019

Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.

Nature communications

Li SZ,Shu QP,Song Y,Zhang HH,Liu Y,Jin BX,Liuyu TZ,Li C,Huang XC,Du RL,Song W,Zhong B,Zhang XD

Fri Jul 19 00:00:00 UTC 2019

TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression.

Biochimica et biophysica acta. Molecular cell research

Qiu Y,Liu P,Ma X,Ma X,Zhu L,Lin Y,You Y,Yu W,Ma D,Sun C,Qin Z,Zhao Y,Shi J,Han L

Sun Sep 01 00:00:00 UTC 2019

Vesicular Stomatitis Virus Transcription Is Inhibited by TRIM69 in the Interferon-Induced Antiviral State.

Journal of virology

Kueck T,Bloyet LM,Cassella E,Zang T,Schmidt F,Brusic V,Tekes G,Pornillos O,Whelan SPJ,Bieniasz PD

Sun Dec 15 00:00:00 UTC 2019

Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.

Cell host & microbe

Binning JM,Chesarino NM,Emerman M,Gross JD

Wed Dec 11 00:00:00 UTC 2019

Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.

PloS one

Zhao Y,Zhang Y,Vazirinejad Mehdiabad M,Zhou K,Chen Y,Li L,Guo J,Xu C

Wed Mar 11 00:00:00 UTC 2020

The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.

Cell reports

Wang K,Ma H,Liu H,Ye W,Li Z,Cheng L,Zhang L,Lei Y,Shen L,Zhang F

Tue May 14 00:00:00 UTC 2019

KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly.

Cells

Liu Y,Yin W,Wang J,Lei Y,Sun G,Li W,Huang Z,Guo M

Tue Dec 10 00:00:00 UTC 2019

Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells.

Chemico-biological interactions

Wu XY,Chen XM,Zhou MX,Hu HX,Zhang JZ,Wang XN,Ren DM,Lou HX,Shen T

Sun Sep 01 00:00:00 UTC 2019

TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis.

British journal of cancer

Zhang G,Zhu Q,Fu G,Hou J,Hu X,Cao J,Peng W,Wang X,Chen F,Cui H

Sun Dec 01 00:00:00 UTC 2019

SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG.

Cell death & disease

Tan P,Xu Y,Du Y,Wu L,Guo B,Huang S,Zhu J,Li B,Lin F,Yao L

Thu Oct 17 00:00:00 UTC 2019

FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.

Developmental cell

Ji S,Liu Q,Zhang S,Chen Q,Wang C,Zhang W,Xiao C,Li Y,Nian C,Li J,Li J,Geng J,Hong L,Xie C,He Y,Chen X,Li X,Yin ZY,You H,Lin KH,Wu Q,Yu C,Johnson RL,Wang L,Chen L,Wang F,Zhou D

Mon Feb 25 00:00:00 UTC 2019

Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation.

Cell reports

Tan G,Yi Z,Song H,Xu F,Li F,Aliyari R,Zhang H,Du P,Ding Y,Niu J,Wang X,Su L,Qin FX,Cheng G

Tue Dec 10 00:00:00 UTC 2019

AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway.

Oncogene

Cui Y,Wu X,Lin C,Zhang X,Ye L,Ren L,Chen M,Yang M,Li Y,Li M,Li J,Guan J,Song L

Mon Jul 01 00:00:00 UTC 2019

p32 is a negative regulator of p53 tetramerization and transactivation.

Molecular oncology

Ghate NB,Kim J,Shin Y,Situ A,Ulmer TS,An W

Sun Sep 01 00:00:00 UTC 2019

A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.

iScience

Chen D,Liu X,Xia T,Tekcham DS,Wang W,Chen H,Li T,Lu C,Ning Z,Liu X,Liu J,Qi H,He H,Piao HL

Fri Jun 28 00:00:00 UTC 2019

An isopentenyl-substituted flavonoid norartocarpin activates Nrf2 signalling pathway and prevents oxidative insults in human lung epithelial cells.

Free radical research

Yang WJ,He JX,Zhou MX,Huang M,Wang SQ,Wang XN,Lou HX,Ren DM,Shen T

Fri Mar 01 00:00:00 UTC 2019

In-Frame Variants in STAG3 Gene Cause Premature Ovarian Insufficiency.

Frontiers in genetics

Xiao WJ,He WB,Zhang YX,Meng LL,Lu GX,Lin G,Tan YQ,Du J

Mon Sep 28 00:00:00 UTC 2020

Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells.

Cell reports

Wu Y,Liu W,Chen J,Liu S,Wang M,Yang L,Chen C,Qi M,Xu Y,Qiao Z,Yan R,Kou X,Zhao Y,Shen B,Yin J,Wang H,Gao Y,Gao S

Tue Nov 19 00:00:00 UTC 2019

BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.

Cell adhesion & migration

Cheng Z,Xin H,Han T

Sun Dec 01 00:00:00 UTC 2019

FBXW7 suppresses epithelial-mesenchymal transition and chemo-resistance of non-small-cell lung cancer cells by targeting snai1 for ubiquitin-dependent degradation.

Cell proliferation

Xiao G,Li Y,Wang M,Li X,Qin S,Sun X,Liang R,Zhang B,Du N,Xu C,Ren H,Liu D

Mon Oct 01 00:00:00 UTC 2018

Extracellular ATP Acts on Jasmonate Signaling to Reinforce Plant Defense.

Plant physiology

Tripathi D,Zhang T,Koo AJ,Stacey G,Tanaka K

Mon Jan 01 00:00:00 UTC 2018

Extracellular ATP Acts on Jasmonate Signaling to Reinforce Plant Defense.

Plant physiology

Tripathi D,Zhang T,Koo AJ,Stacey G,Tanaka K

Mon Jan 01 00:00:00 UTC 2018

Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.

Journal of virology

Shen Z,Ye G,Deng F,Wang G,Cui M,Fang L,Xiao S,Fu ZF,Peng G

Thu Mar 01 00:00:00 UTC 2018

Structural Basis for the Inhibition of Host Gene Expression by Porcine Epidemic Diarrhea Virus nsp1.

Journal of virology

Shen Z,Ye G,Deng F,Wang G,Cui M,Fang L,Xiao S,Fu ZF,Peng G

Thu Mar 01 00:00:00 UTC 2018

Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.

IUBMB life

Wu Q,Yu S,Chen J,Li Y,Gao Y

Thu Feb 01 00:00:00 UTC 2018

Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.

IUBMB life

Wu Q,Yu S,Chen J,Li Y,Gao Y

Thu Feb 01 00:00:00 UTC 2018

Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis.

Experimental cell research

Guo P,Qiu Y,Ma X,Li T,Ma X,Zhu L,Lin Y,Han L

Sun Jul 01 00:00:00 UTC 2018

Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis.

Experimental cell research

Guo P,Qiu Y,Ma X,Li T,Ma X,Zhu L,Lin Y,Han L

Sun Jul 01 00:00:00 UTC 2018

Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis.

Experimental cell research

Guo P,Qiu Y,Ma X,Li T,Ma X,Zhu L,Lin Y,Han L

Sun Jul 01 00:00:00 UTC 2018

Tripartite motif 31 promotes resistance to anoikis of hepatocarcinoma cells through regulation of p53-AMPK axis.

Experimental cell research

Guo P,Qiu Y,Ma X,Li T,Ma X,Zhu L,Lin Y,Han L

Sun Jul 01 00:00:00 UTC 2018

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide.

ACS omega

Derf A,Mudududdla R,Akintade D,Williams IS,Abdullaha M,Chaudhuri B,Bharate SB

Fri Aug 31 00:00:00 UTC 2018

Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity.

Neoplasia (New York, N.Y.)

Liu H,Xie Y,Zhang Z,Mao P,Liu J,Ma W,Zhao Y

Sat Sep 01 00:00:00 UTC 2018

Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity.

Neoplasia (New York, N.Y.)

Liu H,Xie Y,Zhang Z,Mao P,Liu J,Ma W,Zhao Y

Sat Sep 01 00:00:00 UTC 2018

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.

Journal of experimental & clinical cancer research : CR

Ma S,Lu CC,Yang LY,Wang JJ,Wang BS,Cai HQ,Hao JJ,Xu X,Cai Y,Zhang Y,Wang MR

Mon Aug 06 00:00:00 UTC 2018

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.

Journal of experimental & clinical cancer research : CR

Ma S,Lu CC,Yang LY,Wang JJ,Wang BS,Cai HQ,Hao JJ,Xu X,Cai Y,Zhang Y,Wang MR

Mon Aug 06 00:00:00 UTC 2018

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.

Journal of experimental & clinical cancer research : CR

Ma S,Lu CC,Yang LY,Wang JJ,Wang BS,Cai HQ,Hao JJ,Xu X,Cai Y,Zhang Y,Wang MR

Mon Aug 06 00:00:00 UTC 2018

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.

Journal of experimental & clinical cancer research : CR

Ma S,Lu CC,Yang LY,Wang JJ,Wang BS,Cai HQ,Hao JJ,Xu X,Cai Y,Zhang Y,Wang MR

Mon Aug 06 00:00:00 UTC 2018

TRIM65 supports bladder urothelial carcinoma cell aggressiveness by promoting ANXA2 ubiquitination and degradation.

Cancer letters

Wei WS,Chen X,Guo LY,Li XD,Deng MH,Yuan GJ,He LY,Li YH,Zhang ZL,Jiang LJ,Chen RX,Ma XD,Wei S,Ma NF,Liu ZW,Luo JH,Zhou FJ,Xie D

Sun Oct 28 00:00:00 UTC 2018

Overexpression of NRK1 ameliorates diet- and age-induced hepatic steatosis and insulin resistance.

Biochemical and biophysical research communications

Fan R,Cui J,Ren F,Wang Q,Huang Y,Zhao B,Wei L,Qian X,Xiong X

Sat Jun 02 00:00:00 UTC 2018

Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.

The Journal of biological chemistry

Yan T,Zhang A,Shi F,Chang F,Mei J,Liu Y,Zhu Y

Fri Jun 29 00:00:00 UTC 2018

Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.

The Journal of biological chemistry

Yan T,Zhang A,Shi F,Chang F,Mei J,Liu Y,Zhu Y

Fri Jun 29 00:00:00 UTC 2018

Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.

Cell death & disease

Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S

Tue Jul 03 00:00:00 UTC 2018

Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.

Cell death & disease

Zhang Y,Li A,Shi J,Fang Y,Gu C,Cai J,Lin C,Zhao L,Liu S

Tue Jul 03 00:00:00 UTC 2018

9-cis-retinoic acid elevates MRP3 expression by inhibiting sumoylation of RXRα to alleviate cholestatic liver injury.

Biochemical and biophysical research communications

Yuan Z,Wang G,Qu J,Wang X,Li K

Mon Sep 03 00:00:00 UTC 2018

SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.

Frontiers in cellular and infection microbiology

Li P,Jin Y,Qi F,Wu F,Luo S,Cheng Y,Montgomery RR,Qian F

Wed Apr 10 00:00:00 UTC 2019

SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.

Frontiers in cellular and infection microbiology

Li P,Jin Y,Qi F,Wu F,Luo S,Cheng Y,Montgomery RR,Qian F

Wed Apr 10 00:00:00 UTC 2019

SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.

Frontiers in cellular and infection microbiology

Li P,Jin Y,Qi F,Wu F,Luo S,Cheng Y,Montgomery RR,Qian F

Wed Apr 10 00:00:00 UTC 2019

SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.

Frontiers in cellular and infection microbiology

Li P,Jin Y,Qi F,Wu F,Luo S,Cheng Y,Montgomery RR,Qian F

Wed Apr 10 00:00:00 UTC 2019

Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity.

Journal of immunology (Baltimore, Md. : 1950)

Zheng Z,Yang J,Jiang X,Liu Y,Zhang X,Li M,Zhang M,Fu M,Hu K,Wang H,Luo MH,Gong P,Hu Q

Sun Jul 01 00:00:00 UTC 2018

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.

The Journal of experimental medicine

Lang X,Tang T,Jin T,Ding C,Zhou R,Jiang W

Wed Feb 01 00:00:00 UTC 2017

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.

The Journal of experimental medicine

Lang X,Tang T,Jin T,Ding C,Zhou R,Jiang W

Wed Feb 01 00:00:00 UTC 2017

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.

Molecular therapy : the journal of the American Society of Gene Therapy

Yin C,Zhang T,Qu X,Zhang Y,Putatunda R,Xiao X,Li F,Xiao W,Zhao H,Dai S,Qin X,Mo X,Young WB,Khalili K,Hu W

Wed May 03 00:00:00 UTC 2017

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.

Molecular therapy : the journal of the American Society of Gene Therapy

Yin C,Zhang T,Qu X,Zhang Y,Putatunda R,Xiao X,Li F,Xiao W,Zhao H,Dai S,Qin X,Mo X,Young WB,Khalili K,Hu W

Wed May 03 00:00:00 UTC 2017

USP25 regulates Wnt signaling by controlling the stability of tankyrases.

Genes & development

Xu D,Liu J,Fu T,Shan B,Qian L,Pan L,Yuan J

Mon May 15 00:00:00 UTC 2017

USP25 regulates Wnt signaling by controlling the stability of tankyrases.

Genes & development

Xu D,Liu J,Fu T,Shan B,Qian L,Pan L,Yuan J

Mon May 15 00:00:00 UTC 2017

PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.

CNS neuroscience & therapeutics

Yang W,Yang LF,Song ZQ,Shah SZA,Cui YY,Li CS,Zhao HF,Gao HL,Zhou XM,Zhao DM

Mon May 01 00:00:00 UTC 2017

PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.

CNS neuroscience & therapeutics

Yang W,Yang LF,Song ZQ,Shah SZA,Cui YY,Li CS,Zhao HF,Gao HL,Zhou XM,Zhao DM

Mon May 01 00:00:00 UTC 2017

Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.

Journal of virology

Xin QL,Deng CL,Chen X,Wang J,Wang SB,Wang W,Deng F,Zhang B,Xiao G,Zhang LK

Thu Jun 15 00:00:00 UTC 2017

Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection.

Journal of virology

Xin QL,Deng CL,Chen X,Wang J,Wang SB,Wang W,Deng F,Zhang B,Xiao G,Zhang LK

Thu Jun 15 00:00:00 UTC 2017

Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.

American journal of cancer research

Li S,Sun A,Liang X,Ma L,Shen L,Li T,Zheng L,Shang W,Zhao W,Jia J

Wed Sep 30 00:00:00 UTC 2020

Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.

American journal of cancer research

Li S,Sun A,Liang X,Ma L,Shen L,Li T,Zheng L,Shang W,Zhao W,Jia J

Wed Sep 30 00:00:00 UTC 2020

Chibby1 knockdown promotes mesenchymal-to-epithelial transition-like changes.

Cell cycle (Georgetown, Tex.)

Fischer V,Wong M,Li FQ,Takemaru KI

Sat Mar 04 00:00:00 UTC 2017

Chibby1 knockdown promotes mesenchymal-to-epithelial transition-like changes.

Cell cycle (Georgetown, Tex.)

Fischer V,Wong M,Li FQ,Takemaru KI

Sat Mar 04 00:00:00 UTC 2017

DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.

Molecular and cellular biology

Liu H,Yan S,Ding J,Yu TT,Cheng SY

Fri Sep 15 00:00:00 UTC 2017

DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.

Molecular and cellular biology

Liu H,Yan S,Ding J,Yu TT,Cheng SY

Fri Sep 15 00:00:00 UTC 2017

MicroRNA-1254 inhibits the migration of colon adenocarcinoma cells by targeting PSMD10.

Journal of digestive diseases

Chu YM,Peng HX,Xu Y,Yang DM,Zhou FL,Li J,Kuai R,Lin Y

Wed Mar 01 00:00:00 UTC 2017

MicroRNA-1254 inhibits the migration of colon adenocarcinoma cells by targeting PSMD10.

Journal of digestive diseases

Chu YM,Peng HX,Xu Y,Yang DM,Zhou FL,Li J,Kuai R,Lin Y

Wed Mar 01 00:00:00 UTC 2017

Nuclear import of Nkx2-2 is mediated by multiple pathways.

Biochemical and biophysical research communications

Lin W,Xu P,Guo Y,Jia Q,Tao T

Sun Jan 22 00:00:00 UTC 2017

Nuclear import of Nkx2-2 is mediated by multiple pathways.

Biochemical and biophysical research communications

Lin W,Xu P,Guo Y,Jia Q,Tao T

Sun Jan 22 00:00:00 UTC 2017

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells.

PloS one

Javidi-Parsijani P,Niu G,Davis M,Lu P,Atala A,Lu B

Wed Sep 13 00:00:00 UTC 2017

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells.

PloS one

Javidi-Parsijani P,Niu G,Davis M,Lu P,Atala A,Lu B

Wed Sep 13 00:00:00 UTC 2017

Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins.

Scientific reports

Foglieni C,Papin S,Salvadè A,Afroz T,Pinton S,Pedrioli G,Ulrich G,Polymenidou M,Paganetti P

Wed Oct 25 00:00:00 UTC 2017

Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins.

Scientific reports

Foglieni C,Papin S,Salvadè A,Afroz T,Pinton S,Pedrioli G,Ulrich G,Polymenidou M,Paganetti P

Wed Oct 25 00:00:00 UTC 2017

HRD1 sensitizes breast cancer cells to Tamoxifen by promoting S100A8 degradation.

Oncotarget

Wang Y,Guo A,Liang X,Li M,Shi M,Li Y,Jenkins G,Lin X,Wei X,Jia Z,Feng X,Su D,Guo W

Tue Apr 04 00:00:00 UTC 2017

HRD1 sensitizes breast cancer cells to Tamoxifen by promoting S100A8 degradation.

Oncotarget

Wang Y,Guo A,Liang X,Li M,Shi M,Li Y,Jenkins G,Lin X,Wei X,Jia Z,Feng X,Su D,Guo W

Tue Apr 04 00:00:00 UTC 2017

Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).

eLife

Erickson T,Morgan CP,Olt J,Hardy K,Busch-Nentwich E,Maeda R,Clemens R,Krey JF,Nechiporuk A,Barr-Gillespie PG,Marcotti W,Nicolson T

Tue May 23 00:00:00 UTC 2017

Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt).

eLife

Erickson T,Morgan CP,Olt J,Hardy K,Busch-Nentwich E,Maeda R,Clemens R,Krey JF,Nechiporuk A,Barr-Gillespie PG,Marcotti W,Nicolson T

Tue May 23 00:00:00 UTC 2017

Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) β3 and is essential for mouse palatogenesis.

The Journal of biological chemistry

Wu BX,Li A,Lei L,Kaneko S,Wallace C,Li X,Li Z

Fri Nov 03 00:00:00 UTC 2017

Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) β3 and is essential for mouse palatogenesis.

The Journal of biological chemistry

Wu BX,Li A,Lei L,Kaneko S,Wallace C,Li X,Li Z

Fri Nov 03 00:00:00 UTC 2017

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.

Nature neuroscience

Sivadasan R,Hornburg D,Drepper C,Frank N,Jablonka S,Hansel A,Lojewski X,Sterneckert J,Hermann A,Shaw PJ,Ince PG,Mann M,Meissner F,Sendtner M

Thu Dec 01 00:00:00 UTC 2016

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.

Nature neuroscience

Sivadasan R,Hornburg D,Drepper C,Frank N,Jablonka S,Hansel A,Lojewski X,Sterneckert J,Hermann A,Shaw PJ,Ince PG,Mann M,Meissner F,Sendtner M

Thu Dec 01 00:00:00 UTC 2016

Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.

Autophagy

Gao J,Li M,Qin S,Zhang T,Jiang S,Hu Y,Deng Y,Zhang C,You D,Li H,Mu D,Zhang Z,Jiang C

Mon Dec 26 00:00:00 UTC 2016

Cytosolic PINK1 promotes the targeting of ubiquitinated proteins to the aggresome-autophagy pathway during proteasomal stress.

Autophagy

Gao J,Li M,Qin S,Zhang T,Jiang S,Hu Y,Deng Y,Zhang C,You D,Li H,Mu D,Zhang Z,Jiang C

Mon Dec 26 00:00:00 UTC 2016

The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.

Cancer research

Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J

Mon Aug 15 00:00:00 UTC 2016

The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.

Cancer research

Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J

Mon Aug 15 00:00:00 UTC 2016

Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.

Oncogene

Li L,Fang R,Liu B,Shi H,Wang Y,Zhang W,Zhang X,Ye L

Thu Aug 04 00:00:00 UTC 2016

Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.

Oncogene

Li L,Fang R,Liu B,Shi H,Wang Y,Zhang W,Zhang X,Ye L

Thu Aug 04 00:00:00 UTC 2016

The Essential Role of Drp1 and Its Regulation by S-Nitrosylation of Parkin in Dopaminergic Neurodegeneration: Implications for Parkinson's Disease.

Antioxidants & redox signaling

Zhang Z,Liu L,Jiang X,Zhai S,Xing D

Mon Oct 10 00:00:00 UTC 2016

The Essential Role of Drp1 and Its Regulation by S-Nitrosylation of Parkin in Dopaminergic Neurodegeneration: Implications for Parkinson's Disease.

Antioxidants & redox signaling

Zhang Z,Liu L,Jiang X,Zhai S,Xing D

Mon Oct 10 00:00:00 UTC 2016

The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients.

Molecular biology of the cell

Inoue T,Tsai B

Sun May 15 00:00:00 UTC 2016

The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients.

Molecular biology of the cell

Inoue T,Tsai B

Sun May 15 00:00:00 UTC 2016

Evolution of IFN-λ in tetrapod vertebrates and its functional characterization in green anole lizard (Anolis carolinensis).

Developmental and comparative immunology

Chen SN,Zhang XW,Li L,Ruan BY,Huang B,Huang WS,Zou PF,Fu JP,Zhao LJ,Li N,Nie P

Mon Aug 01 00:00:00 UTC 2016

Evolution of IFN-λ in tetrapod vertebrates and its functional characterization in green anole lizard (Anolis carolinensis).

Developmental and comparative immunology

Chen SN,Zhang XW,Li L,Ruan BY,Huang B,Huang WS,Zou PF,Fu JP,Zhao LJ,Li N,Nie P

Mon Aug 01 00:00:00 UTC 2016

USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1.

Genes & development

Xu D,Shan B,Sun H,Xiao J,Zhu K,Xie X,Li X,Liang W,Lu X,Qian L,Yuan J

Mon Aug 01 00:00:00 UTC 2016

Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.

International journal of molecular sciences

Wu B,Zhou Y,Wang Y,Yang XM,Liu ZY,Li JH,Feng F,Chen ZN,Jiang JL

Thu Nov 10 00:00:00 UTC 2016

Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.

International journal of molecular sciences

Wu B,Zhou Y,Wang Y,Yang XM,Liu ZY,Li JH,Feng F,Chen ZN,Jiang JL

Thu Nov 10 00:00:00 UTC 2016

Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization.

The Journal of biological chemistry

Murphy J,Kolandaivelu S

Fri Oct 28 00:00:00 UTC 2016

Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization.

The Journal of biological chemistry

Murphy J,Kolandaivelu S

Fri Oct 28 00:00:00 UTC 2016

Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.

PloS one

Ren S,Wang J,Chen TL,Li HY,Wan YS,Peng NF,Gui XE,Zhu Y

Mon Aug 29 00:00:00 UTC 2016

Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.

PloS one

Ren S,Wang J,Chen TL,Li HY,Wan YS,Peng NF,Gui XE,Zhu Y

Mon Aug 29 00:00:00 UTC 2016

Protein-protein interaction between ezrin and p65 in human breast cancer cells.

Genetics and molecular research : GMR

Tang R,Li FX,Shao WF,Wen QS,Yu XR,Xiong JB

Thu Jun 30 00:00:00 UTC 2016

Protein-protein interaction between ezrin and p65 in human breast cancer cells.

Genetics and molecular research : GMR

Tang R,Li FX,Shao WF,Wen QS,Yu XR,Xiong JB

Thu Jun 30 00:00:00 UTC 2016

Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.

Parasites & vectors

Li M,Zhang X,Gong P,Li J

Mon Aug 08 00:00:00 UTC 2016

Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.

Parasites & vectors

Li M,Zhang X,Gong P,Li J

Mon Aug 08 00:00:00 UTC 2016

Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.

Autophagy

Xu D,Zhang T,Xiao J,Zhu K,Wei R,Wu Z,Meng H,Li Y,Yuan J

Fri Apr 03 00:00:00 UTC 2015

Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.

Autophagy

Xu D,Zhang T,Xiao J,Zhu K,Wei R,Wu Z,Meng H,Li Y,Yuan J

Fri Apr 03 00:00:00 UTC 2015

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner.

British journal of cancer

Zhang Q,Wang H,Wu X,Liu B,Liu W,Wang R,Liang X,Ma C,Gao L

Tue Nov 17 00:00:00 UTC 2015

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner.

British journal of cancer

Zhang Q,Wang H,Wu X,Liu B,Liu W,Wang R,Liang X,Ma C,Gao L

Tue Nov 17 00:00:00 UTC 2015

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner.

British journal of cancer

Zhang Q,Wang H,Wu X,Liu B,Liu W,Wang R,Liang X,Ma C,Gao L

Tue Nov 17 00:00:00 UTC 2015

TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner.

British journal of cancer

Zhang Q,Wang H,Wu X,Liu B,Liu W,Wang R,Liang X,Ma C,Gao L

Tue Nov 17 00:00:00 UTC 2015

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

Molecular cancer therapeutics

Liu Q,Xu X,Zhao M,Wei Z,Li X,Zhang X,Liu Z,Gong Y,Shao C

Sun Feb 01 00:00:00 UTC 2015

Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway.

Molecular cancer therapeutics

Liu Q,Xu X,Zhao M,Wei Z,Li X,Zhang X,Liu Z,Gong Y,Shao C

Sun Feb 01 00:00:00 UTC 2015

BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.

The international journal of biochemistry & cell biology

Liao S,Du R,Wang L,Qu Z,Cui X,Li C,Liu F,Huang M,Wang J,Chen J,Gao M,Yu S,Tang Z,Li DW,Jiang T,Liu M

Sun Nov 01 00:00:00 UTC 2015

BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.

The international journal of biochemistry & cell biology

Liao S,Du R,Wang L,Qu Z,Cui X,Li C,Liu F,Huang M,Wang J,Chen J,Gao M,Yu S,Tang Z,Li DW,Jiang T,Liu M

Sun Nov 01 00:00:00 UTC 2015

pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation.

Cellular signalling

Chen J,Liu F,Li H,Archacki S,Gao M,Liu Y,Liao S,Huang M,Wang J,Yu S,Li C,Tang Z,Liu M

Sun Nov 01 00:00:00 UTC 2015

pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation.

Cellular signalling

Chen J,Liu F,Li H,Archacki S,Gao M,Liu Y,Liao S,Huang M,Wang J,Yu S,Li C,Tang Z,Liu M

Sun Nov 01 00:00:00 UTC 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 UTC 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 UTC 2015

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.

eLife

Xu D,Shan B,Lee BH,Zhu K,Zhang T,Sun H,Liu M,Shi L,Liang W,Qian L,Xiao J,Wang L,Pan L,Finley D,Yuan J

Mon Nov 02 00:00:00 UTC 2015

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.

eLife

Xu D,Shan B,Lee BH,Zhu K,Zhang T,Sun H,Liu M,Shi L,Liang W,Qian L,Xiao J,Wang L,Pan L,Finley D,Yuan J

Mon Nov 02 00:00:00 UTC 2015

A new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency.

Cell & bioscience

He J,Huang L,Qiu H,Li J,Luo L,Li Y,Tian S,Kang K,Luo J,Liu L,Gou D

Wed Dec 09 00:00:00 UTC 2015

A new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency.

Cell & bioscience

He J,Huang L,Qiu H,Li J,Luo L,Li Y,Tian S,Kang K,Luo J,Liu L,Gou D

Wed Dec 09 00:00:00 UTC 2015

Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.

Blood cancer journal

Sun X,Lu B,Hu B,Xiao W,Li W,Huang Z

Fri Mar 28 00:00:00 UTC 2014

Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.

Blood cancer journal

Sun X,Lu B,Hu B,Xiao W,Li W,Huang Z

Fri Mar 28 00:00:00 UTC 2014

Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.

Infection and immunity

Xie HX,Lu JF,Rolhion N,Holden DW,Nie P,Zhou Y,Yu XJ

Fri Aug 01 00:00:00 UTC 2014

Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.

Infection and immunity

Xie HX,Lu JF,Rolhion N,Holden DW,Nie P,Zhou Y,Yu XJ

Fri Aug 01 00:00:00 UTC 2014

The RNA binding of protein A from Wuhan nodavirus is mediated by mitochondrial membrane lipids.

Virology

Qiu Y,Miao M,Wang Z,Liu Y,Yang J,Xia H,Li XF,Qin CF,Hu Y,Zhou X

Fri Aug 01 00:00:00 UTC 2014

The RNA binding of protein A from Wuhan nodavirus is mediated by mitochondrial membrane lipids.

Virology

Qiu Y,Miao M,Wang Z,Liu Y,Yang J,Xia H,Li XF,Qin CF,Hu Y,Zhou X

Fri Aug 01 00:00:00 UTC 2014

Inhibition of Hepatitis B virus replication by SAMHD1.

Biochemical and biophysical research communications

Chen Z,Zhu M,Pan X,Zhu Y,Yan H,Jiang T,Shen Y,Dong X,Zheng N,Lu J,Ying S,Shen Y

Fri Aug 08 00:00:00 UTC 2014

Inhibition of Hepatitis B virus replication by SAMHD1.

Biochemical and biophysical research communications

Chen Z,Zhu M,Pan X,Zhu Y,Yan H,Jiang T,Shen Y,Dong X,Zheng N,Lu J,Ying S,Shen Y

Fri Aug 08 00:00:00 UTC 2014

The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.

PloS one

Qiu Y,Wang Z,Liu Y,Han Y,Miao M,Qi N,Yang J,Xia H,Li X,Qin CF,Hu Y,Zhou X

Tue Jan 20 00:00:00 UTC 2015

The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.

PloS one

Qiu Y,Wang Z,Liu Y,Han Y,Miao M,Qi N,Yang J,Xia H,Li X,Qin CF,Hu Y,Zhou X

Tue Jan 20 00:00:00 UTC 2015

Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene.

Acta biochimica et biophysica Sinica

Liu Z,Luo X,Liu L,Zhao W,Guo S,Guo Y,Wang N,He H,Liao X,Ma W,Zhou H,Zhang T

Sun Dec 01 00:00:00 UTC 2013

Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene.

Acta biochimica et biophysica Sinica

Liu Z,Luo X,Liu L,Zhao W,Guo S,Guo Y,Wang N,He H,Liao X,Ma W,Zhou H,Zhang T

Sun Dec 01 00:00:00 UTC 2013

Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization.

PloS one

Xu LR,Liu XL,Chen J,Liang Y

Tue Apr 29 00:00:00 UTC 2014

Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization.

PloS one

Xu LR,Liu XL,Chen J,Liang Y

Tue Apr 29 00:00:00 UTC 2014

Pericentrin contains five NESs and an NLS essential for its nucleocytoplasmic trafficking during the cell cycle.

Cell research

Liu Q,Yu J,Zhuo X,Jiang Q,Zhang C

Sun Aug 01 00:00:00 UTC 2010

Pericentrin contains five NESs and an NLS essential for its nucleocytoplasmic trafficking during the cell cycle.

Cell research

Liu Q,Yu J,Zhuo X,Jiang Q,Zhang C

Sun Aug 01 00:00:00 UTC 2010

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HA tag Polyclonal Antibody

HA tag Antibody (51064-2-AP) in ICC/IF

Product Details

51064-2-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

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