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Product Details
PA5-117046
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 234-513 of human SPINT1 (NP_0037011)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901676
Product Specific Information
Positive Samples: Mouse liver, Rat brain
Immunogen sequence: ANVTVTVLST KQTEDYCLAS NKVGRCRGSF PRWYYDPTEQ ICKSFVYGGC LGNKNNYLRE EECILACRGV QGPSMERRHP VCSGTCQPTQ FRCSNGCCID SFLECDDTPN CPDASDEAAC EKYTSGFDEL QRIHFPSDKG HCVDLPDTGL CKESIPRWYY NPFSEHCARF TYGGCYGNKN NFEEEQQCLE SCRGISKKDV FGLRREIPIP STGSVEMAVA VFLVICIVVV VAILGYCFFK NQRKDFHGHH HHPPPTPASS TVSTTEDTEH LVYNHTTRPL
Target Information
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HAI-1; hepatocyte growth factor activator inhibitor 1; Hepatocyte growth factor activator inhibitor type 1; hepatocyte growth factor activator inhibitor-1; Kunitz-type protease inhibitor 1; serine protease inhibitor, Kunitz type 1
Gene Aliases: HAI; HAI-1; HAI1; MANSC2; SPINT1; UNQ223/PRO256
UniProt ID: (Human) O43278, (Mouse) Q9R097
Entrez Gene ID: (Human) 6692, (Mouse) 20732, (Rat) 311331
neural tube closure
embryonic placenta development
negative regulation of peptidase activity
extracellular matrix organization
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
negative regulation of endopeptidase activity
positive regulation of glial cell differentiation
cellular response to BMP stimulus
negative regulation of neural precursor cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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