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HAI-2 Antibody (PA5-119410) in IHC (P)
Immunohistochemistry analysis of HAI-2 in paraffin-embedded Human Liver tissue. Samples were incubated with polyclonal antibody (Product # PA5-119410) at a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
Product Details
PA5-119410
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein Serine Peptidase Inhibitor Kunitz Type 2. The antigen corresponds to amino acid range 28-197 of the target protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2903908
Target Information
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ45571; HAI-2; Hepatocyte growth factor activator inhibitor type 2; Kunitz-type protease inhibitor 2; Placental bikunin; serine peptidase inhibitor, Kunitz type, 2; serine protease inhibitor, Kunitz type 2; serine protease inhibitor, Kunitz type, 2; testicular tissue protein Li 183
Gene Aliases: DIAR3; HAI-2; HAI2; KOP; PB; SPINT2
UniProt ID: (Human) O43291
Entrez Gene ID: (Human) 10653, (Rat) 292770
neural tube closure
proteolysis
establishment or maintenance of cell polarity
negative regulation of endopeptidase activity
epithelial cell morphogenesis involved in placental branching
basement membrane organization
movement of cell or subcellular component
negative regulation of cell-cell adhesion
negative regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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