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Bioss
HB9/HLXB9 Polyclonal Antibody
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FIGURE: 1 / 2
HB9/HLXB9 Antibody (BS-11320R) in Flow
RSC96 (Positive) and HL-60 (Negative control) cells (black) were fixed with 4% PFA for 10 min at room temperature, permeabilized with 90% ice-cold methanol for 20 min at -20°C, and incubated in 5% BSA blocking buffer for 30 min at room temperature. Cells were then stained with HB9/HLXB9 Antibody (bs-11320R) at 1:50 dilution in blocking buffer and incubated for 30 min at room temperature, washed twice with 2% BSA in PBS, followed by secondary antibody (blue) incubation for 40 min at room temperature. Acquisitions of 20,000 events were perfo... View More
Product Details
BS-11320R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HLXB9, amino acids 231-330.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Homeobox protein HB9 is expressed in lymphoid and pancreatic tissues. It is reported to be Putative transcription factor involved in pancreas development and function. Defects in this gene causes Currarino syndrome. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. It is also reported that HB9 is strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeobox gene HB9; homeobox HB9; Homeobox protein HB9; HOX SCRA1; Motor neuron and pancreas homeobox 1; Motor neuron and pancreas homeobox protein 1
Gene Aliases: HB9; HLXB9; HOXHB9; MNR2; MNX1; SCRA1
UniProt ID: (Human) P50219, (Rat) M0R6D8
Entrez Gene ID: (Human) 3110, (Rat) 682076, (Mouse) 15285
neuron migration
regulation of transcription, DNA-templated
motor neuron axon guidance
biological_process
post-embryonic development
spinal cord motor neuron cell fate specification
nerve development
dorsal/ventral neural tube patterning
central nervous system neuron differentiation
neuron differentiation
pancreas development
endocrine pancreas development
cell morphogenesis involved in neuron differentiation
neuron projection morphogenesis
diaphragm development
respiratory system development
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
humoral immune response
anatomical structure morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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