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Invitrogen
HDJ2 Polyclonal Antibody
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Product Details
PA5-88165
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 178-397 of human DNAJA1 (NP_0015301)
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804707
Product Specific Information
Immunogen sequence: MECQGHGERI SPKDRCKSCN GRKIVREKKI LEVHIDKGMK DGQKITFHGE GDQEPGLEPG DIIIVLDQKD HAVFTRRGED LFMCMDIQLV EALCGFQKPI STLDNRTIVI TSHPGQIVKH GDIKCVLNEG MPIYRRPYEK GRLIIEFKVN FPENGFLSPD KLSLLEKLLP ERKEVEETDE MDQVELVDFD PNQERRRHYN GEAYEDDEHH PRGGVQCQTS; Positive Samples: MCF7, HeLa, Jurkat, U-87MG, HepG2, Mouse brain, Mouse kidney, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Lipid-anchor, Membrane, Microsome, Mitochondrion, Nucleus, perinuclear region
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1. 6 kb and a protein product with a molecular weight of about 35 kDa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily A, member 1; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; h HSJ-2; hDj-2; Heat shock 40 kDa protein 4; Heat shock protein J2; heat shock protein, DNAJ-like 2; HSDJ; HSJ-2; Human DnaJ protein 2; neural precursor cell expressed, developmentally down-regulated 7; neural precursor cell expressed, developmentally down-regulated gene 7
Gene Aliases: DJ-2; DjA1; DNAJ2; DNAJA1; hDJ-2; HDJ2; HSDJ; HSJ-2; HSJ2; HSPF4; NEDD7
UniProt ID: (Human) P31689, (Mouse) P63037
Entrez Gene ID: (Human) 3301, (Mouse) 15502
G-protein coupled receptor binding
protein binding
ATP binding
Hsp70 protein binding
Tat protein binding
ubiquitin protein ligase binding
metal ion binding
low-density lipoprotein particle receptor binding
unfolded protein binding
chaperone binding
C3HC4-type RING finger domain binding
heat shock protein binding
protein folding
spermatogenesis
response to heat
sperm motility
androgen receptor signaling pathway
negative regulation of protein ubiquitination
protein refolding
DNA damage response, detection of DNA damage
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of JUN kinase activity
regulation of protein transport
protein localization to mitochondrion
toxin transport
response to unfolded protein
negative regulation of establishment of protein localization to mitochondrion
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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