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Immunogen sequence: RHQHDFDENGI IYWIGTNAKT AYEWVNPAAY GLVVVTSSEG RNLPYGRLED ILSRDNSALN CHSNDDKNAW FAIDLGLWVI PSAYTLRHAR GYGRSALRNW VFQVSKDGQD W
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 98%.
Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ligase for inhibin receptor; E3 ubiquitin-protein ligase HECTD1; EULIR; HECT domain containing E3 ubiquitin protein ligase 1; HECT domain-containing protein 1
Gene Aliases: EULIR; HECTD1; KIAA1131
UniProt ID: (Human) Q9ULT8
Entrez Gene ID: (Human) 25831
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