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HIP1R Antibody (MA1-16750) in IHC (P)
Immunohistochemical analysis of HIP1R in formalin-fixed paraffin-embedded tissue section of human kidney. Samples were incubated in HIP1R monoclonal antibody (Product # MA1-16750) using a dilution of 1:200 followed by HRP labeled anti-rabbit secondary antibody and DAB reagent. Nuclei of cells were counter-stained with hematoxylin. This HIP1 related antibody generated strong staining of the cytoplasm and mem... View More
Product Details
MA1-16750
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1E1
Immunogen
Human HIP1r-TALIN Homology Region (57 kDa).
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2248284
Product Specific Information
Suggested positive control: HeLa whole cell lysate and rat brain homogenate, Hela whole cell lysate, antigen standard for IFT57 (transient overexpression lysate), rat brain protein.
Target Information
Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HIP-12; HIP1-related protein; huntingtin interacting protein 12; Huntingtin-interacting protein 1-related protein; Huntingtin-interacting protein 12
Gene Aliases: AA410023; HIP12; HIP1R; HIP3; ILWEQ; KIAA0655; mKIAA0655
UniProt ID: (Human) O75146, (Mouse) Q9JKY5
Entrez Gene ID: (Human) 9026, (Mouse) 29816, (Rat) 81917
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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