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Invitrogen
HIPK2 Polyclonal Antibody
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HIPK2 Antibody (PA5-14470) in IHC (P)
Immunohistochemistry analysis of HIPK2 in formalin-fixed and paraffin-embedded human hepatocarcinoma tissue. Samples were incubated with HIPK2 polyclonal antibody (Product # PA5-14470) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-14470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 437-468 amino acids from the center region of human HIPK2
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2117722
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
HIPK2 is a nuclear serine/threonine kinase that is linked to transcriptional regulation and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hHIPk2; Homeodomain-interacting protein kinase 2
Gene Aliases: HIPK2; PRO0593
UniProt ID: (Human) Q9H2X6
Entrez Gene ID: (Human) 28996
negative regulation of transcription from RNA polymerase II promoter
eye development
transcription, DNA-templated
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
transforming growth factor beta receptor signaling pathway
smoothened signaling pathway
adult walking behavior
positive regulation of cell proliferation
anterior/posterior pattern specification
retina layer formation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
modulation by virus of host morphology or physiology
neuron differentiation
erythrocyte differentiation
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
PML body organization
positive regulation of protein binding
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of DNA binding
negative regulation of neuron apoptotic process
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
embryonic camera-type eye morphogenesis
voluntary musculoskeletal movement
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cell cycle
embryonic retina morphogenesis in camera-type eye
lens induction in camera-type eye
SMAD protein signal transduction
iris morphogenesis
cellular response to hypoxia
intrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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