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This antibody is predicted to react with bovine, chicken, mouse, non-human primate, rat and Xenopus and zebrafish based on sequence homology.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bpof DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H2B histone family, member R; H2B/r; histone 1, H2bj; Histone H2B type 1-J; Histone H2B.1; Histone H2B.r
Gene Aliases: H2B/r; H2BC11; H2BFR; H2BJ; HIST1H2BJ
UniProt ID: (Human) P06899
Entrez Gene ID: (Human) 8970
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