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Invitrogen
HIST1H2BL Polyclonal Antibody
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FIGURE: 1 / 4
HIST1H2BL Antibody (PA5-48429) in WB
Western blot analysis of Histone H2BL was performed by loading 20 µg of Nuclear protein extracts from BEAS-2B (lane 1), and 150 ng of Purified Histones containing H2BL (lane 2) and Histone Octamer containing canonical H2B (lane 3) in sample buffer and 5 µL Spectra Multicolor Broad Range Protein Ladder (Product # 26634) onto a 15% polyacrylamide gel. Proteins were transferred to PVDF membrane (Product # 88518) at 65V for 90 min on ice. Membrane was blocked in 5% Milk in PBST for 1 hour at room temperature. Histone H2BL was detected at appro... View More
Product Details
PA5-48429
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BL.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633886
Product Specific Information
Predicted to react with mouse based on sequence homology.
Target Information
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H2B histone family, member C; H2B/c; histone 1, H2bl; Histone H2B type 1-L; Histone H2B.c; Histone H2Bc
Gene Aliases: dJ97D16.4; H2B/c; H2BC13; H2BFC; HIST1H2BL
UniProt ID: (Human) Q99880
Entrez Gene ID: (Human) 8340
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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