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Invitrogen
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Immunogen sequence: KESYSIYVYK VLKQVHPDTG ISSKAM
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H2b 613; H2B histone family, member Q; H2B-clustered histone 21; H2B/q; histone 2, H2be; Histone H2B type 2-E; Histone H2B-GL105; Histone H2B.q; Histone H2Bq
Gene Aliases: AV127319; GL105; H2B; H2b-613; H2B.1; H2BC21; H2BFQ; H2BGL105; H2BQ; HIST2H2BE; T25626
UniProt ID: (Human) Q16778, (Mouse) Q64524
Entrez Gene ID: (Human) 8349, (Mouse) 319190
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