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Product Details
10445-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HIST3H2A Fusion Protein Ag0374 (1-130 aa encoded by BC001193)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGRGKQGG KARAKAKSRS SRAGLQFPVG RVHRLLRKGN YSERVGAGAP VYLAAVLEYL TAEILELAGN AARDNKKTRI IPRHLQLAIR NDEELNKLLG RVTIAQGGVL PNIQAVLLPK KTESHHKAKG K (1-130 aa encoded by BC001193)
Target Information
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: H2A-clustered histone 25; histone 2a; histone 3, H2a; Histone cluster 3, H2a; Histone H2A type 3
Gene Aliases: H2a; H2AC25; H2AW; HIST3H2A
UniProt ID: (Human) Q7L7L0, (Rat) Q4FZT6, (Mouse) Q8BFU2
Entrez Gene ID: (Human) 92815, (Rat) 64646, (Mouse) 319162
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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