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Invitrogen
HK1 Recombinant Rabbit Monoclonal Antibody (1N8E9)
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FIGURE: 1 / 2
HK1 Antibody (MA5-51518) in ICC/IF
Immunocytochemistry (confocal imaging) analysis of HK1 in HeLa cells. Samples were incubated with HK1 Recombinant monoclonal antibody (Product # MA5-51518) using a dilution of 1:100 (Red). The cells were counterstained with alpha-Tubulin Mouse mAb (Product # MA5-38221, dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 60x.
Product Details
MA5-51518
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1N8E9
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human HK1 (NP_000179.2).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3094198
Product Specific Information
Immunogen sequence: KIDKYLYAMR LSDETLIDIM TRFRKEMKNG LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVHMESE VYDTPENIVH GSGSQLFDHV AECLGDFMEK RKIKDKKLPV GFTFSFPCQQ SKIDEAILIT WTKRFKASGV EGADVVKLLN KAIKKRGDYD ANIVAVVNDT VGTMMTCGY
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase I; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I
Gene Aliases: BB404130; dea; HEXOKIN; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Rat) 25058, (Mouse) 15275
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
mannokinase activity
protein kinase activity
ATPase activity
protein complex binding
protein homodimerization activity
nucleotide binding
catalytic activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
cellular glucose homeostasis
glycolytic process
glucose transport
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
response to ischemia
protein phosphorylation
regulation of anion channel activity
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
hexose metabolic process
negative regulation of apoptotic process
protein autophosphorylation
carbohydrate metabolic process
metabolic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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