Product References
Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters.
The Journal of cell biology
Stempels FC,Jiang M,Warner HM,Moser ML,Janssens MH,Maassen S,Nelen IH,de Boer R,Jiemy WF,Knight D,Selley J,O'Cualain R,Baranov MV,Burgers TCQ,Sansevrino R,Milovanovic D,Heeringa P,Jones MC,Vlijm R,Ter Beest M,van den Bogaart G
14-9983-82 was used in Immunocytochemistry to propose that the ESCRT proteins are recruited to adhesion-induced membrane tears to induce extracellular shedding of the damaged membrane.
Mon Jul 03 00:00:00 UTC 2023
Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity.
Nature communications
Piekarska K,Urban-Wójciuk Z,Kurkowiak M,Pelikant-Małecka I,Schumacher A,Sakowska J,Spodnik JH,Arcimowicz Ł,Zielińska H,Tymoniuk B,Renkielska A,Siebert J,Słomińska E,Trzonkowski P,Hupp T,Marek-Trzonkowska NM
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Mon Feb 14 00:00:00 UTC 2022
Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.
Frontiers in immunology
Lemaître F,Carmena Moratalla A,Farzam-Kia N,Carpentier Solorio Y,Tastet O,Cleret-Buhot A,Guimond JV,Haddad E,Arbour N
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Neutralization
Wed Oct 20 00:00:00 UTC 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
14-9983-82 was used in Flow Cytometry to conclude that the combination of chidamide and anti-programmed cell death 1 therapy represents a potentially important strategy for soft tissue sarcoma.
Mon Feb 01 00:00:00 UTC 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
14-9983-82 was used in Flow Cytometry to conclude that the combination of chidamide and anti-programmed cell death 1 therapy represents a potentially important strategy for soft tissue sarcoma.
Mon Feb 01 00:00:00 UTC 2021
Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential.
Molecular cancer therapeutics
Tivadar ST,McIntosh RS,Chua JX,Moss R,Parsons T,Zaitoun AM,Madhusudan S,Durrant LG,Vankemmelbeke M
14-9983-82 was used in Western Blot to describe the characterization of the mAb, FG129, which targets tumor-associated sialylated glycan, and demonstrate its potential for multimodal cancer therapy.
Sun Mar 01 00:00:00 UTC 2020
Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential.
Molecular cancer therapeutics
Tivadar ST,McIntosh RS,Chua JX,Moss R,Parsons T,Zaitoun AM,Madhusudan S,Durrant LG,Vankemmelbeke M
14-9983-82 was used in Western Blot to describe the characterization of the mAb, FG129, which targets tumor-associated sialylated glycan, and demonstrate its potential for multimodal cancer therapy.
Sun Mar 01 00:00:00 UTC 2020
Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2.
Molecular therapy. Methods & clinical development
Cabanes-Creus M,Westhaus A,Navarro RG,Baltazar G,Zhu E,Amaya AK,Liao SHY,Scott S,Sallard E,Dilworth KL,Rybicki A,Drouyer M,Hallwirth CV,Bennett A,Santilli G,Thrasher AJ,Agbandje-McKenna M,Alexander IE,Lisowski L
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Fri Jun 12 00:00:00 UTC 2020
TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
International journal of oncology
Uchida E,Suwa S,Yoshimoto R,Watanabe K,Kasama T,Miura O,Fukuda T
14-9983 was used in Flow cytometry/Cell sorting to study the association between chronic myeloid leukemia (CML) and T-lymphokine-activated killer cell-originated protein kinase (TOPK).
Wed May 01 00:00:00 UTC 2019
Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment.
Journal of oncology
Li M,Liu Z,Wang X
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Thu Mar 31 00:00:00 UTC 2022
Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.
Proteomics
Lanoix J,Durette C,Courcelles M,Cossette É,Comtois-Marotte S,Hardy MP,Côté C,Perreault C,Thibault P
14-9983-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation to compare approaches for the isolation of two different B-cell lymphoblast cell models, and report on the recovery, reproducibility, scalability, and complementarity of identification from each method.
Fri Jun 01 00:00:00 UTC 2018
HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells.
Nature biotechnology
Gornalusse GG,Hirata RK,Funk SE,Riolobos L,Lopes VS,Manske G,Prunkard D,Colunga AG,Hanafi LA,Clegg DO,Turtle C,Russell DW
14-9983 was used in Flow cytometry/Cell sorting to study the prevention of the 'missing-self' response in pluripotent stem cells through the expression of minimally polymorphic HLA-E molecules.
Tue Aug 01 00:00:00 UTC 2017
Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells.
Cancer immunology research
Olson BM,Gamat M,Seliski J,Sawicki T,Jeffery J,Ellis L,Drake CG,Weichert J,McNeel DG
14-9983 was used in Flow cytometry/Cell sorting to suggest that ADT combined with AR-directed immunotherapy targets a major mechanism of resistance, overexpression of the AR.
Fri Dec 01 00:00:00 UTC 2017
A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes.
Frontiers in immunology
Forget MA,Tavera RJ,Haymaker C,Ramachandran R,Malu S,Zhang M,Wardell S,Fulbright OJ,Toth CL,Gonzalez AM,Thorsen ST,Flores E,Wahl A,Peng W,Amaria RN,Hwu P,Bernatchez C
14-9983 was used in Inhibition experiments to develop a method for the efficient production of large numbers of GMP-grade, gene modified TIL for the treatment of adoptive cell therapy.
Mon Aug 07 00:00:00 UTC 2023
Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.
PloS one
Sethumadhavan S,Silva M,Philbrook P,Nguyen T,Hatfield SM,Ohta A,Sitkovsky MV
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Wed Dec 06 00:00:00 UTC 2017
Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models.
Stem cell reports
Sugita S,Makabe K,Fujii S,Iwasaki Y,Kamao H,Shiina T,Ogasawara K,Takahashi M
14-9983 was used in Flow cytometry/Cell sorting to determine if retinal pigment epithelium (RPE) transplantation could be performed using allografts, and whether this would produce RPE-specific antibodies.
Tue Nov 14 00:00:00 UTC 2017
Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose.
Proceedings of the National Academy of Sciences of the United States of America
Lever M,Lim HS,Kruger P,Nguyen J,Trendel N,Abu-Shah E,Maini PK,van der Merwe PA,Dushek O
14-9983 was used in Functional assays to show that the KPL-IFF model correctly predicts the T-cell response to antigen copresentation.
Tue Oct 25 00:00:00 UTC 2016
Human CD8(+) T Cells Target Multiple Epitopes in Respiratory Syncytial Virus Polymerase.
Viral immunology
Burbulla D,Günther PS,Peper JK,Jahn G,Dennehy KM
14-9983 was used in Functional assays to identify respiratory syncytial virus peptide epitopes that are presented by common human leukocyte antigen types.
Wed Jun 01 00:00:00 UTC 2016
Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.
Stem cell research & therapy
Camilleri ET,Gustafson MP,Dudakovic A,Riester SM,Garces CG,Paradise CR,Takai H,Karperien M,Cool S,Sampen HJ,Larson AN,Qu W,Smith J,Dietz AB,van Wijnen AJ
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Thu Aug 11 00:00:00 UTC 2016
Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies.
PloS one
Matsushita M,Otsuka Y,Tsutsumida N,Tanaka C,Uchiumi A,Ozawa K,Suzuki T,Ichikawa D,Aburatani H,Okamoto S,Kawakami Y,Hattori Y
14-9983 was used in Blocking experiments to reveal that the PEPP2 gene was highly expressed in myeloid leukemia cells and some other hematological malignancies.
Tue Jul 26 00:00:00 UTC 2016
A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.
eLife
Gowen BG,Chim B,Marceau CD,Greene TT,Burr P,Gonzalez JR,Hesser CR,Dietzen PA,Russell T,Iannello A,Coscoy L,Sentman CL,Carette JE,Muljo SA,Raulet DH
14-9983 was used in Chromatin immunoprecipitation to offer insight into the stress pathways that alert the immune system to danger.
Fri Nov 13 00:00:00 UTC 2015
Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.
Oncotarget
Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Tue Oct 06 00:00:00 UTC 2015
Nonclassical antigen-processing pathways are required for MHC class II-restricted direct tumor recognition by NY-ESO-1-specific CD4(+) T cells.
Cancer immunology research
Matsuzaki J,Tsuji T,Luescher I,Old LJ,Shrikant P,Gnjatic S,Odunsi K
14-9983-82 was used in Functional assays to demonstrate that cancer cells selectively present peptides from intracellular tumour antigens on MHC class II by multiple nonclassical antigen-processing pathways.
Tue Apr 01 00:00:00 UTC 2014
Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing.
Journal of virology
Frias-Staheli N,Dorner M,Marukian S,Billerbeck E,Labitt RN,Rice CM,Ploss A
14-9983 was used in Flow cytometry/Cell sorting to investigate use of humanized "bone marrow liver thymus" mice as a model for immunological studies and for antiviral testing.
Sat Feb 01 00:00:00 UTC 2014
Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.
Stem cells (Dayton, Ohio)
Fernandez I,Ooi TP,Roy K
Published figure using HLA-ABC monoclonal antibody (Product # 14-9983-82) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2014
Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity.
Journal of immunology (Baltimore, Md. : 1950)
O'Connor GM,Vivian JP,Widjaja JM,Bridgeman JS,Gostick E,Lafont BA,Anderson SK,Price DA,Brooks AG,Rossjohn J,McVicar DW
14-9983 was used in Functional assays to identify important residues within KIR3DL1 for its role in HLA recognition.
Sat Mar 15 00:00:00 UTC 2014
Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors.
The Journal of biological chemistry
Stahlschmidt W,Robertson MJ,Robinson PJ,McCluskey A,Haucke V
14-9983 was used in Immunocytochemistry to study the role of clathrin in intracellular membrane traffic.
Fri Feb 21 00:00:00 UTC 2014
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.
Cell host & microbe
Smith W,Tomasec P,Aicheler R,Loewendorf A,Nemčovičová I,Wang EC,Stanton RJ,Macauley M,Norris P,Willen L,Ruckova E,Nomoto A,Schneider P,Hahn G,Zajonc DM,Ware CF,Wilkinson GW,Benedict CA
14-9983-82 was used in Flow cytometry/Cell sorting to identify human cytomegalovirus UL141 glycoprotein as necessary and sufficient to restrict TRAIL death receptor function.
Wed Mar 13 00:00:00 UTC 2013
Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma.
British journal of haematology
Kang YJ,Zeng W,Song W,Reinhold B,Choi J,Brusic V,Yamashita T,Munshi A,Li C,Minvielle S,Anderson KC,Munshi N,Reinherz EL,Sasada T
14-9983-82 was used in Inhibition experiments to identify novel human leucocyte antigen (HLA)-A*0201 (HLA-A2)-restricted cytotoxic T lymphocyte epitopes from a B cell specific molecule HLA-DOβ (DOB) as a potential target for multiple myeloma.
Fri Nov 01 00:00:00 UTC 2013
Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo.
Journal of virology
Palomares K,Vigant F,Van Handel B,Pernet O,Chikere K,Hong P,Sherman SP,Patterson M,An DS,Lowry WE,Mikkola HK,Morizono K,Pyle AD,Lee B
14-9983 was used in Flow cytometry/Cell sorting to show that the extraordinary specificity of NiV-G for ephrinB2 holds promise for targeting specific ephrinB2(+) populations in vivo or in vitro.
Fri Feb 01 00:00:00 UTC 2013
Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo.
Journal of virology
Palomares K,Vigant F,Van Handel B,Pernet O,Chikere K,Hong P,Sherman SP,Patterson M,An DS,Lowry WE,Mikkola HK,Morizono K,Pyle AD,Lee B
14-9983 was used in Flow cytometry/Cell sorting to show that the extraordinary specificity of NiV-G for ephrinB2 holds promise for targeting specific ephrinB2(+) populations in vivo or in vitro.
Fri Feb 01 00:00:00 UTC 2013
Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.
Current protocols in immunology
Sidney J,Southwood S,Moore C,Oseroff C,Pinilla C,Grey HM,Sette A
14-9983 was used in in vitro experiments to describe a technique for the direct and quantitative measurement of the capacity of peptide ligands to bind MHC molecules.
Fri Feb 01 00:00:00 UTC 2013
Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.
Current protocols in immunology
Sidney J,Southwood S,Moore C,Oseroff C,Pinilla C,Grey HM,Sette A
14-9983 was used in in vitro experiments to describe a technique for the direct and quantitative measurement of the capacity of peptide ligands to bind MHC molecules.
Fri Feb 01 00:00:00 UTC 2013
Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.
Current protocols in immunology
Sidney J,Southwood S,Moore C,Oseroff C,Pinilla C,Grey HM,Sette A
14-9983 was used in in vitro experiments to describe a technique for the direct and quantitative measurement of the capacity of peptide ligands to bind MHC molecules.
Fri Feb 01 00:00:00 UTC 2013
Up-regulation of cytolytic functions of human Vδ2-γ T lymphocytes through engagement of ILT2 expressed by tumor target cells.
Blood
Harly C,Peyrat MA,Netzer S,Déchanet-Merville J,Bonneville M,Scotet E
14-9983 was used in Flow cytometry/Cell sorting to describe a new cytotoxic T lymphocyte activation pathway involving MHC class I engagement on gamma delta T cells.
Thu Mar 10 00:00:00 UTC 2011
Isolation and characterization of human trophoblast side-population (SP) cells in primary villous cytotrophoblasts and HTR-8/SVneo cell line.
PloS one
Takao T,Asanoma K,Kato K,Fukushima K,Tsunematsu R,Hirakawa T,Matsumura S,Seki H,Takeda S,Wake N
14-9983 was used in Immunocytochemistry to suggest that IL7R and IL1R2 are available as markers to detect human trophoblast side-population cells.
Thu Oct 13 00:00:00 UTC 2011
Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity.
The Journal of clinical investigation
Ha SP,Klemen ND,Kinnebrew GH,Brandmaier AG,Marsh J,Hangoc G,Palmer DC,Restifo NP,Cornetta K,Broxmeyer HE,Touloukian CE
14-9983 was used in Flow cytometry/Cell sorting to study how a translational model of immunotherapy, utilising unique properties of HSC transplantation, has potential for the treatment of metastatic melanoma.
Wed Dec 01 00:00:00 UTC 2010
Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein.
PLoS pathogens
Francica JR,Varela-Rohena A,Medvec A,Plesa G,Riley JL,Bates P
14-9983 was used in Flow cytometry/Cell sorting to investigate the mechanism by which MHC1 and β1 integrin is downregulated by Ebola viral infection.
Thu Sep 09 00:00:00 UTC 2010
Antibodies and lentiviruses that specifically recognize a T cell epitope derived from HIV-1 Nef protein and presented by HLA-C.
Journal of immunology (Baltimore, Md. : 1950)
Herschhorn A,Marasco WA,Hizi A
14-9983 was used in an ELISA assay to demonstrate that Abs and PVs with TCR-like specificity are likely to be highly valuable as building blocks for specific targeting and killing of HIV-1-infected cells.
Wed Dec 15 00:00:00 UTC 2010
Differential effects of concomitant use of vitamins C and E on trophoblast apoptosis and autophagy between normoxia and hypoxia-reoxygenation.
PloS one
Hung TH,Chen SF,Li MJ,Yeh YL,Hsieh TT
14-9983-82 was used in Immunopurification to investigate whether concomitant administration of vitamins C and E during pregnancy detrimentally affects trophoblast cells during hypoxia-reoxygenation.
Mon Aug 16 00:00:00 UTC 2010
Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders.
Blood
Azakami K,Sato T,Araya N,Utsunomiya A,Kubota R,Suzuki K,Hasegawa D,Izumi T,Fujita H,Aratani S,Fujii R,Yagishita N,Kamijuku H,Kanekura T,Seino K,Nishioka K,Nakajima T,Yamano Y
14-9983 was used in Flow cytometry/Cell sorting to assess the contribution of iNKT cells to the immune defence against human T-lymphotropic virus type 1 and associated disorders.
Thu Oct 08 00:00:00 UTC 2009
Critical role of Lck in L-selectin signaling induced by sulfatides engagement.
Journal of leukocyte biology
Xu T,Chen L,Shang X,Cui L,Luo J,Chen C,Ba X,Zeng X
14-9983 was used in Western Blotting to suggest that Lck plays a critical role in L-selectin signaling upon sulfatides stimulation.
Wed Oct 01 00:00:00 UTC 2008
c-Abl is required for the signaling transduction induced by L-selectin ligation.
European journal of immunology
Chen C,Shang X,Xu T,Cui L,Luo J,Ba X,Hao S,Zeng X
14-9983 was used in Functional assays to study the role of c-Abl in accepting and transferring the upstream activation events induced by L-selectin ligation.
Thu Nov 01 00:00:00 UTC 2007
Engagement of PSGL-1 enhances beta(2)-integrin-involved adhesion of neutrophils to recombinant ICAM-1.
Acta pharmacologica Sinica
Wang XG,Cheng YP,Ba XQ
14-9983 was used in Flow cytometry/Cell sorting to demonstrate that P-selectin glycoprotein ligand 1-transduced signals can enhance beta(2)-integrin-involved adhesion of neutrophils to the recombinant intercellular adhesion molecule-1.
Mon May 01 00:00:00 UTC 2006
High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss.
Human immunology
Koene GJ,Arts-Hilkes YH,van Dijk AJ,van der Ven KJ,Slootweg PJ,de Weger RA,Tilanus MG
Wed Dec 01 00:00:00 UTC 2004
A study of human leukocyte antigen G expression in hydatidiform moles.
American journal of obstetrics and gynecology
Goldman-Wohl D,Ariel I,Greenfield C,Hochner-Celnikier D,Lavy Y,Yagel S
Wed Aug 01 00:00:00 UTC 2001
