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Proteintech
HMG20A Monoclonal Antibody (1B10F12)
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Product Details
66676-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B10F12
Immunogen
HMG20A Fusion Protein Ag2718 (1-347 aa encoded by BC021959)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MENLMTSST LPPLFADEDG SKESNDLATT GLNHPEVPYS SGATSSTNNP EFVEDLSQGQ LLQSESSNAA EGNEQRHEDE QRSKRGGWSK GRKRKKPLRD SNAPKSPLTG YVRFMNERRE QLRAKRPEVP FPEITRMLGN EWSKLPPEEK QRYLDEADRD KERYMKELEQ YQKTEAYKVF SRKTQDRQKG KSHRQDAARQ ATHDHEKETE VKERSVFDIP IFTEEFLNHS KAREAELRQL RKSNMEFEER NAALQKHVES MRTAVEKLEV DVIQERSRNT VLQQHLETLR QVLTSSFASM PLPGSGETPT VDTIDSYMNR LHSIILANPQ DNENFIATVR EVVNRLDR (1-347 aa encoded by BC021959)
Target Information
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ10739; High mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; iBRAF; Inhibitor of BRAF35
Gene Aliases: 1200004E06Rik; 5730490E10Rik; HMG20A; HMGX1; HMGXB1; Ibraf
UniProt ID: (Human) Q9NP66, (Mouse) Q9DC33
Entrez Gene ID: (Human) 10363, (Mouse) 66867
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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