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Invitrogen
HMGB3 Polyclonal Antibody
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HMGB3 Antibody (PA5-23361) in WB
Western blot analysis of HMGB3 in mouse placenta lysate in the 1) absence and 2) presence of immunizing peptide. Samples were incubated in HMGB3 polyclonal antibody (Product # PA5-23361) using a dilution of 3 µg/mL followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
Product Details
PA5-23361
Product Specifications
Species Reactivity
Bovine,
Horse,
Human,
Marsupial,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 1-50 of human HMGB3
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540884
Target Information
HMGB3 belongs to the high mobility group protein superfamily. Like HMG1 and HMG2, HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: high mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; high mobilty group protein 2A; high-mobility group (nonhistone chromosomal) protein 4; high-mobility group box 3; high-mobility group protein 4; HMG-2a; HMG-4; HMGB3 transcript variant 1/2; MGC90319
Gene Aliases: BOS_25378; HMG-2a; HMG-4; HMG2A; HMG4; HMGB3; RGD1564407
UniProt ID: (Bovine) Q32L31, (Human) O15347, (Mouse) O54879
Entrez Gene ID: (Bovine) 613729, (Human) 3149, (Rat) 305373, (Mouse) 15354
chromatin remodeling
regulation of transcription, DNA-templated
negative regulation of B cell differentiation
negative regulation of myeloid cell differentiation
DNA recombination
transcription, DNA-templated
multicellular organism development
DNA geometric change
innate immune response
negative regulation of cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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