Proteintech

HMMR Polyclonal Antibody

HMMR Antibody in Immunocytochemistry (ICC/IF)

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HMMR Antibody (15820-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using HMMR-Specific antibody (Product # 15820-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

HMMR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

15820-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 5 publications 5 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Antibodies raised against RHAMM have been reported to recognize proteins of 56, 66 and 70 kDa in the supernatant of murine 3T3 fibroblasts. Some of the isoforms detectable by anti-RHAMM antibodies, including the 52 kDa form and a 48-49 kDa form found in 10T1/2 cells, have been speculated to be underglycosylated precursor forms of the mature RHAMM protein.

Target Information

The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Single-cell transcriptomic analysis identifies a highly replicating Cd168⁺ skeletal stem/progenitor cell population in mouse long bones.

Journal of genetics and genomics = Yi chuan xue bao

Hao RC,Li ZL,Wang FY,Tang J,Li PL,Yin BF,Li XT,Han MY,Mao N,Liu B,Ding L,Zhu H

Fri Sep 01 00:00:00 UTC 2023

Single-cell transcriptomic analysis identifies a highly replicating Cd168⁺ skeletal stem/progenitor cell population in mouse long bones.

Journal of genetics and genomics = Yi chuan xue bao

Hao RC,Li ZL,Wang FY,Tang J,Li PL,Yin BF,Li XT,Han MY,Mao N,Liu B,Ding L,Zhu H

Fri Sep 01 00:00:00 UTC 2023

Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.

International journal of molecular sciences

Lu JH,Chueh KS,Juan TJ,Mao JW,Lin RJ,Lee YC,Shen MC,Sun TW,Lin HY,Juan YS

Thu May 04 00:00:00 UTC 2023

Hmmr Acts as a Key Regulator in the ADSCs Proliferation and Mitosis.

Stem cell reviews and reports

Zhang X,Huang D,Li K,Han C,Li H,Li C,Liu L

Tue Aug 01 00:00:00 UTC 2023

Hmmr Acts as a Key Regulator in the ADSCs Proliferation and Mitosis.

Stem cell reviews and reports

Zhang X,Huang D,Li K,Han C,Li H,Li C,Liu L

Tue Aug 01 00:00:00 UTC 2023

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop.

Cell death discovery

Guo K,Liu C,Shi J,Lai C,Gao Z,Luo J,Li Z,Tang Z,Li K,Xu K

Tue Feb 07 00:00:00 UTC 2023

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop.

Cell death discovery

Guo K,Liu C,Shi J,Lai C,Gao Z,Luo J,Li Z,Tang Z,Li K,Xu K

Tue Feb 07 00:00:00 UTC 2023

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop.

Cell death discovery

Guo K,Liu C,Shi J,Lai C,Gao Z,Luo J,Li Z,Tang Z,Li K,Xu K

Tue Feb 07 00:00:00 UTC 2023

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop.

Cell death discovery

Guo K,Liu C,Shi J,Lai C,Gao Z,Luo J,Li Z,Tang Z,Li K,Xu K

Tue Feb 07 00:00:00 UTC 2023

Development and validation of a combined metabolism and immune prognostic model in lung adenocarcinoma.

Journal of thoracic disease

Shi Y,Dai S,Lei Y

Thu Dec 01 00:00:00 UTC 2022

The mechanism of acentrosomal spindle assembly in human oocytes.

Science (New York, N.Y.)

Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L

Fri Nov 18 00:00:00 UTC 2022

Oleate acid-stimulated HMMR expression by CEBPα is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma.

International journal of biological sciences

Zhang D,Liu J,Xie T,Jiang Q,Ding L,Zhu J,Ye Q

Mon Apr 04 00:00:00 UTC 2022

Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.

Cellular signalling

Cooper LM,Hanson A,Kavanagh JA,Waddell DS

Mon Jun 01 00:00:00 UTC 2020

A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.

Journal of cellular physiology

Rao VK,Zavala G,Deb Roy A,Mains RE,Eipper BA

Sat Jun 01 00:00:00 UTC 2019

A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.

Journal of cellular physiology

Rao VK,Zavala G,Deb Roy A,Mains RE,Eipper BA

Sat Jun 01 00:00:00 UTC 2019

Tracing haematopoietic stem cell formation at single-cell resolution.

Nature

Zhou F,Li X,Wang W,Zhu P,Zhou J,He W,Ding M,Xiong F,Zheng X,Li Z,Ni Y,Mu X,Wen L,Cheng T,Lan Y,Yuan W,Tang F,Liu B

Thu May 26 00:00:00 UTC 2016

Tracing haematopoietic stem cell formation at single-cell resolution.

Nature

Zhou F,Li X,Wang W,Zhu P,Zhou J,He W,Ding M,Xiong F,Zheng X,Li Z,Ni Y,Mu X,Wen L,Cheng T,Lan Y,Yuan W,Tang F,Liu B

Thu May 26 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: CD168; Hyaluronan mediated motility receptor; hyaluronan-mediated motility receptor; hyaluronan-mediated motility receptor (RHAMM); Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility

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Gene Aliases: AA386826; CD168; HMMR; IHABP; RHAMM

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UniProt ID: (Human) O75330, (Mouse) Q00547

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Entrez Gene ID: (Human) 3161, (Rat) 25460, (Mouse) 15366

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Function(s)

protein binding hyaluronic acid binding

Process(es)

G2/M transition of mitotic cell cycle hyaluronan catabolic process cytoskeleton organization cell-cell signaling

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HMMR Polyclonal Antibody

HMMR Antibody (15820-1-AP) in ICC/IF

Product Details

15820-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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