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HNF4G Polyclonal Antibody

HNF4G Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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HNF4G Antibody (25801-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human small intestine tissue slide using 25801-1-AP ( HNF4G Antibody) at dilution of 1:50 (under 40x lens).

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Product Details

25801-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

ChIP assay (ChIP)

Assay-dependent

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HNF4G Fusion Protein Ag22848 (327-408 aa encoded by BC105009)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This polyclonal antibody is raised against C-terminal 82 amino acids of human HNF4-gamma.

Immunogen sequence: GGASNDGSH LHHPMHPHLS QDPLTGQTIL LGPMSTLVHA DQISTPETPL PSPPQGSGQE QYKIAANQAS VISHQHLSKQ KQL (327-408 aa encoded by BC105009)

Target Information

HNF4G is a transcription factor. It has a lower transcription activation potential than HNF4-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

HNF4G stimulates the development of pancreatic cancer by promoting IGF2BP2 transcription.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Zhan J,Zhang Q,Tong X,Liu X,Zhao C

Mon May 01 00:00:00 UTC 2023

HNF4G stimulates the development of pancreatic cancer by promoting IGF2BP2 transcription.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Zhan J,Zhang Q,Tong X,Liu X,Zhao C

Mon May 01 00:00:00 UTC 2023

MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes.

Cell reports

Datta R,Gholampour MA,Yang CD,Volk R,Lin S,Podolsky MJ,Arnold T,Rieder F,Zaro BW,Verzi M,Lehner R,Abumrad N,Lizama CO,Atabai K

Tue Mar 28 00:00:00 UTC 2023

Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.

European journal of pharmacology

Chen L,Shi H,Wang X,Wang T,Wang Y,Wu Z,Zhang W,Chen H,Zhong M,Mao X,Shi X,Li Q

Sat Feb 05 00:00:00 UTC 2022

Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.

European journal of pharmacology

Chen L,Shi H,Wang X,Wang T,Wang Y,Wu Z,Zhang W,Chen H,Zhong M,Mao X,Shi X,Li Q

Sat Feb 05 00:00:00 UTC 2022

Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation.

Protein & cell

Wang C,Zhang T,Liao Q,Dai M,Guo J,Yang X,Tan W,Lin D,Wu C,Zhao Y

Mon Feb 01 00:00:00 UTC 2021

Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation.

Protein & cell

Wang C,Zhang T,Liao Q,Dai M,Guo J,Yang X,Tan W,Lin D,Wu C,Zhao Y

Mon Feb 01 00:00:00 UTC 2021

Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.

Clinical & experimental metastasis

Huang Y,Xiang Y,Xie Z,Cai Y,Yang Q,Huang H,Chen Z,Xiao Z,He Q

Sat Aug 01 00:00:00 UTC 2020

Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance.

Cancer cell

Shukla S,Cyrta J,Murphy DA,Walczak EG,Ran L,Agrawal P,Xie Y,Chen Y,Wang S,Zhan Y,Li D,Wong EWP,Sboner A,Beltran H,Mosquera JM,Sher J,Cao Z,Wongvipat J,Koche RP,Gopalan A,Zheng D,Rubin MA,Scher HI,Chi P,Chen Y

Mon Dec 11 00:00:00 UTC 2017

Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance.

Cancer cell

Mon Dec 11 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: hepatocyte nuclear factor 4, gamma; Hepatocyte nuclear factor 4-gamma; HNF-4 gamma; HNF-4-gamma; HNF4 gamma; HNF4-beta; Hnf4gamma; Nuclear receptor subfamily 2 group A member 2

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Gene Aliases: HNF4G; NR2A2; NR2A3

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UniProt ID: (Human) Q14541, (Mouse) Q9WUU6

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Entrez Gene ID: (Human) 3174, (Mouse) 30942

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Function(s)

transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding zinc ion binding sequence-specific DNA binding DNA binding metal ion binding

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated steroid hormone mediated signaling pathway positive regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter intracellular receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HNF4G Polyclonal Antibody

HNF4G Antibody (25801-1-AP) in IHC (P)

Product Details

25801-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Flow Cytometry (Flow)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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