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Proteintech
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Immunogen sequence: MENSQLCKL FIGGLNVQTS ESGLRGHFEA FGTLTDCVVV VNPQTKRSRC FGFVTYSNVE EADAAMAASP HAVDGNTVEL KRAVSREDSA RPGAHAKVKK LFVGGLKGDV AEGDLIEHFS QFGTVEKAEI IADKQSGKKR GFGFVYFQNH DAADKAAVVK FHPIQGHRVE VKKAVPKEDI YSGGGGGGSR SSRGGRGGRG RGGGRDQNGL SKGGGGGYNS YGGYGGGGGG GYNAYGGGGG GSSYGGSDYG NGFGGFGSYS QHQSSYGPMK SGGGGGGGGS SWGGRSNSGP YRGGYGGGGG YGGSSF (1-305 aa encoded by B C019271)
HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.
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Protein Aliases: Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0
Gene Aliases: 1110055B05Rik; 3010025E17Rik; hnRNP A0; HNRNPA0; HNRPA0
UniProt ID: (Human) Q13151, (Mouse) Q9CX86
Entrez Gene ID: (Human) 10949, (Mouse) 77134
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