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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • hnRNP L Antibodies

          Proteintech

          HNRNPL Recombinant Rabbit Monoclonal Antibody (3J22)

          View all (26) hnRNP L antibodies
          Datasheet
          Protocols
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          Datasheet
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          Cite HNRNPL Recombinant Rabbit Monoclonal Antibody (3J22)

          • Antibody Testing Data (3)
          HNRNPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          HNRNPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          HNRNPL Antibody (82259-1-RR) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 82259-1-RR (HNRNPL antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HNRNPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HNRNPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HNRNPL Antibody in Western Blot (WB)

          Product Details

          82259-1-RR

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:19,600
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:400-1:1,600
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Rabbit / IgG

          Expression System

          Mammalian cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          3J22

          Immunogen

          Recombinant protein
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Protein A

          Storage buffer

          PBS with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: FRKNGVQAMV EFDSVQSAQR AKASLNGADI YSGCCTLKIE YAKPTRLNVF KNDQDTWDYT NPNLSGQGDP GSNPNKRQRQ PPLLGDHPAE YGGPHGGYHS HYHDEGYGPP PPHYEGRRMG PPVGGHRRGP SRYGPQYGHP PPPPPPPEYG PHADSPVLMV YGLDQSKMNC DRVFNVFCLY GNVEKVKFMK SKPGAAMVEM ADGYAVDRAI THLNNNFMFG QKLNVCVSKQ PAIMPGQSYG LEDGSCSYKD FSESRNNRFS TPEQAAKNRI QHPSNVLHFF NAPLEVTEEN FFEICDELGV KRPSSVKVFS GKSERSSSGL LEWESKSDAL ETLGFLNHYQ MKNPNGPYPY TLKLCFSTAQ HAS

          Target Information

          Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ35509; Heterogeneous nuclear ribonucleoprotein L; heterogenous nuclear ribonucleoprotein L; hnRNP L

          View more View less

          Gene Aliases: Fblim1; hnRNP-L; HNRNPL; HNRPL; P/OKcl.14

          View more View less

          UniProt ID: (Human) P14866, (Rat) F1LQ48

          View more View less

          Entrez Gene ID: (Human) 3191, (Rat) 80846

          View more View less

          Function(s)
          nucleotide binding RNA binding protein binding transcription regulatory region DNA binding poly(A) RNA binding pre-mRNA intronic binding
          Process(es)
          regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome RNA processing gene expression mRNA processing
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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