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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PSMC3IP Antibodies

          Proteintech

          HOP2 Polyclonal Antibody

          6 References
          View all (4) PSMC3IP antibodies

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          Datasheet
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          Datasheet
          Protocols
          Questions & Answers

          Cite HOP2 Polyclonal Antibody

          • Antibody Testing Data (8)
          HOP2 Antibody in Immunocytochemistry (ICC/IF)
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          HOP2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          HOP2 Antibody (11339-1-AP) in ICC/IF

          Immunofluorescent analysis of HepG2 cells, using PSMC3IP antibody 11339-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HOP2 Antibody in Immunocytochemistry (ICC/IF)
          HOP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HOP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HOP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HOP2 Antibody in Western Blot (WB)
          HOP2 Antibody in Western Blot (WB)
          HOP2 Antibody in Western Blot (WB)
          HOP2 Antibody in Immunoprecipitation (IP)

          Product Details

          11339-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -

          Miscellaneous PubMed (MISC)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          HOP2 Fusion Protein Ag1883 (1-205 aa encoded by BC008792)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MSKGRAEAA AGAAGILLRY LQEQNRPYSS QDVFGNLQRE HGLGKAVVVK TLEQLAQQGK IKEKMYGKQK IYFADQDQFD MVSDADLQVL DGKIVALTAK VQSLQQSCRY MEAEMQKEIQ ELKKECAGYR ERLKNIKAAT NHVTPEEKEQ VYRERQKYCK EWRKRKRMAT ELSDAILEGY PKSKKQFFEE VGIETDEDYN VTLPDP (1-205 aa encoded by B C008792)

          Target Information

          PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DBD-interacting; Homologous-pairing protein 2 homolog; Nuclear receptor coactivator GT198; Proteasome 26S ATPase subunit 3-interacting protein; PSMC3-interacting protein; Tat-binding protein 1-interacting protein; TBP-1-interacting protein

          View more View less

          Gene Aliases: GT198; HOP2; HUMGT198A; ODG3; PSMC3IP; TBPIP

          View more View less

          UniProt ID: (Human) Q9P2W1

          View more View less

          Entrez Gene ID: (Human) 29893

          View more View less

          Function(s)
          DNA binding ligand-dependent nuclear receptor transcription coactivator activity
          Process(es)
          DNA recombination meiotic cell cycle regulation of nucleic acid-templated transcription
          It has to be done as per old AB suggested Products section.
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