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Proteintech
HOP2 Polyclonal Antibody
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Product Details
11339-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HOP2 Fusion Protein Ag1883 (1-205 aa encoded by BC008792)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSKGRAEAA AGAAGILLRY LQEQNRPYSS QDVFGNLQRE HGLGKAVVVK TLEQLAQQGK IKEKMYGKQK IYFADQDQFD MVSDADLQVL DGKIVALTAK VQSLQQSCRY MEAEMQKEIQ ELKKECAGYR ERLKNIKAAT NHVTPEEKEQ VYRERQKYCK EWRKRKRMAT ELSDAILEGY PKSKKQFFEE VGIETDEDYN VTLPDP (1-205 aa encoded by B C008792)
Target Information
PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DBD-interacting; Homologous-pairing protein 2 homolog; Nuclear receptor coactivator GT198; Proteasome 26S ATPase subunit 3-interacting protein; PSMC3-interacting protein; Tat-binding protein 1-interacting protein; TBP-1-interacting protein
Gene Aliases: GT198; HOP2; HUMGT198A; ODG3; PSMC3IP; TBPIP
UniProt ID: (Human) Q9P2W1
Entrez Gene ID: (Human) 29893
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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