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Invitrogen
HOXA1 Polyclonal Antibody
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HOXA1 Antibody (PA5-101116) in IHC (P)
Immunohistochemistry analysis of HOXA1 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with HOXA1 polyclonal antibody (Product # PA5-101116) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-101116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HOXA1(Accession P49639), corresponding to amino acid residues G56-A106.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850560
Product Specific Information
Antibody detects endogenous levels of total HOXA1.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: early retinoic acid 1; homeo box A1; homeobox 1F; homeobox A1; homeobox protein Hox-1.6; Homeobox protein Hox-1F; Homeobox protein Hox-A1; homeoboxless protein ERA-1-399; homeotic protein ERA-1-993; Hox 1.6-like protein; HOX A1 homeodomain protein; HOXA 1; HOXA-1; lab-like protein; MGC45232
Gene Aliases: BSAS; ERA1; Hox-1.6; HOX1; HOX1F; HOXA1
UniProt ID: (Human) P49639
Entrez Gene ID: (Human) 3198, (Mouse) 15394, (Rat) 103690132
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
sensory perception of sound
optokinetic behavior
motor neuron axon guidance
anatomical structure morphogenesis
anterior/posterior pattern specification
rhombomere 3 development
rhombomere 4 development
rhombomere 5 development
abducens nerve formation
facial nerve structural organization
facial nucleus development
central nervous system neuron differentiation
hindbrain development
inner ear morphogenesis
outer ear morphogenesis
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
embryonic neurocranium morphogenesis
inner ear development
artery morphogenesis
regulation of behavior
cognition
neuromuscular process
artery development
semicircular canal formation
cellular response to retinoic acid
cochlea development
cochlea morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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