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HOXA1 Antibody (PA5-19264) in WB
Western blot analysis of HOXA1 using HOXA1 Polyclonal Antibody (Product # PA5-19264) in Lane A: HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human HOXA1 (RC222721) with C-terminal MYC tag probed with HOXA1 Polyclonal Antibody (1 µg/mL). Lane B: Mock-transfected HEK293 probed with HOXA1 Polyclonal Antibody (1 mg/mL). Lane C: transfected HEK293 lysate probed with anti-MYC Tag (1:1,000). Primary incubations were for 1 hour. Detected by chemiluminescence.
Product Details
PA5-19264
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (QPATYQTSGN) corresponding to the internal amino acids of HOXA1 (aa 76-86).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10988854
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box A1; homeobox 1F; Homeobox protein Hox-1F; Homeobox protein Hox-A1; Hox 1.6-like protein; HOX A1 homeodomain protein; HOXA 1; HOXA-1; lab-like protein; MGC45232
Gene Aliases: BSAS; HOX1; HOX1F; HOXA1
UniProt ID: (Human) P49639
Entrez Gene ID: (Human) 3198
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
sensory perception of sound
optokinetic behavior
anatomical structure morphogenesis
abducens nerve formation
outer ear morphogenesis
embryonic neurocranium morphogenesis
inner ear development
artery morphogenesis
regulation of behavior
cognition
neuromuscular process
artery development
semicircular canal formation
cochlea development
cochlea morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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