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Invitrogen
HOXA7 Polyclonal Antibody
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Product Details
PA5-36245
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 100-150 of human Hox-A7
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2553437
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 25 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box A7; Homeobox gene A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1.1; Homeobox protein Hox-1A; Homeobox protein Hox-A7; HOMEOBOX PROTEIN HOX-A7 (HOX-1.1) (M6-12) (M6); Homeobox protein M6-12; homeobox protein R5; hox-1.1; M6
Gene Aliases: ANTP; AV118143; Hox-1.1; HOX1; HOX1.1; HOX1A; Hox1r5; Hoxa-7; HOXA7; M6
UniProt ID: (Human) P31268, (Mouse) P02830
Entrez Gene ID: (Human) 3204, (Mouse) 15404, (Rat) 500126
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor binding
sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
negative regulation of cell-matrix adhesion
negative regulation of leukocyte migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
anterior/posterior pattern specification
negative regulation of keratinocyte differentiation
negative regulation of monocyte differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
stem cell differentiation
angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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