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Abnova
HOXA7 Monoclonal Antibody (2F2)
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Product Details
H00003204-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2F2
Immunogen
HOXA7 (NP_008827, 58 a.a. approximately 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: NSPLYQSPFA SGYGLGADAY GNLPCASYDQ NIPGLCSDLA KGACDKTDEG ALHGA
Target Information
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box A7; Homeobox protein Hox 1.1; Homeobox protein Hox-1A; Homeobox protein Hox-A7
Gene Aliases: ANTP; HOX1; HOX1.1; HOX1A; HOXA7
UniProt ID: (Human) P31268
Entrez Gene ID: (Human) 3204
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
negative regulation of cell-matrix adhesion
negative regulation of leukocyte migration
transcription from RNA polymerase II promoter
anterior/posterior pattern specification
negative regulation of keratinocyte differentiation
negative regulation of monocyte differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
stem cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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